COVID-19 Updates

Visit UC San Diego's Coronavirus portal for the latest information for the campus community.

Publications

2022

JMRI Journal
Time-Resolved Noncontrast Magnetic Resonance Perfusion Imaging of Paraspinal Muscles
Miyazaki M, Yamamoto A, Malis V, Statum S, Chung CB, Sozanski J, Bae WC. Time-Resolved Noncontrast Magnetic Resonance Perfusion Imaging of Paraspinal Muscles. J Magn Reson Imaging. 2022 Feb 22. doi: 10.1002/jmri.28123. Epub ahead of print. PMID: 35191562.
European Journal of Immunology
Characterization of SARS-CoV-2 and common cold coronavirus-specific T-cell responses in MIS-C and Kawasaki disease children
Hsieh LE, Grifoni A, Sidney J, Shimizu C, Shike H, Ramchandar N, Moreno E, Tremoulet AH, Burns JC, Franco A. Characterization of SARS-CoV-2 and common cold coronavirus-specific T-cell responses in MIS-C and Kawasaki disease children. Eur J Immunol. 2022 Jan;52(1):123-137. doi: 10.1002/eji.202149556. Epub 2021 Oct 27. PMID: 34599760; PMCID: PMC8646471.

Supported by the MARC through the Pilot Project Grant program.

 

2021

Frontier in Endocrinology
Feasibility of an Inversion Recovery-Prepared Fat-Saturated Zero Echo Time Sequence for High Contrast Imaging of the Osteochondral Junction
Jang H, Ma Y, Carl M, Lombardi AF, Chang EY, Du J. Feasibility of an Inversion Recovery-Prepared Fat-Saturated Zero Echo Time Sequence for High Contrast Imaging of the Osteochondral Junction. Front Endocrinol (Lausanne). 2021 Dec 24;12:777080. doi: 10.3389/fendo.2021.777080. PMID: 35002964; PMCID: PMC8739813.

J. of Reproductive Immunology
SARS-CoV-2-specific T cell responses and immune regulation in infected pregnant women
Hsieh LE, Grifoni A, Dave H, Wang J, Johnson D, Zellner J, Sidney J, Chambers C, Franco A. SARS-CoV-2-specific T cell responses and immune regulation in infected pregnant women. J Reprod Immunol. 2022 Feb;149:103464. doi: 10.1016/j.jri.2021.103464. Epub 2021 Dec 11. PMID: 34953325; PMCID: PMC8665650.

Supported by the MARC through the Pilot Project Grant program.

Immunohorizons©ImmunoHorizons
Distal Lck Promoter-Driven Cre Shows Cell Type-Specific Function in Innate-like T Cells
Figueroa MG, Parker LM, Krol K, Zhao M. Distal LckPromoter-Driven Cre Shows Cell Type-Specific Function in Innate-like T Cells. Immunohorizons. 2021 Sep 28;5(9):772-781. doi: 10.4049/immunohorizons.2100079. PMID: 34583938.



Supported by the MARC through the Pilot Project Grant program.
Medical Image Analysis
Fat-saturated image generation from multi-contrast MRIs using generative adversarial networks with Bloch equation-based autoencoder regularization
Kim S, Jang H, Hong S, Hong YS, Bae WC, Kim S, Hwang D. Fat-saturated image generation from multi-contrast MRIs using generative adversarial networks with Bloch equation-based autoencoder regularization. Med Image Anal. 2021 Oct;73:102198. doi: 10.1016/j.media.2021.102198. Epub 2021 Jul 30. PMID: 34403931.

EMBO Journal
Calcium signals regulate the functional differentiation of thymic iNKT cells.
Zhao M, Quintana A, Zhang C, Andreyev AY, Kiosses W, Kuwana T, Murphy A, Hogan PG, Kronenberg M. Calcium signals regulate the functional differentiation of thymic iNKT cells. EMBO J. 2021 Aug 16;40(16):e107901. doi: 10.15252/embj.2021107901. Epub 2021 Jun 25. PMID: 34169542; PMCID: PMC8365263. Reproduced with permission from EMBO.
              
 
Supported by the MARC through the Pilot Project Grant program.
Immunity Journal
Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation
Xian H, Liu Y, Rundberg Nilsson A, Gatchalian R, Crother TR, Tourtellotte WG, Zhang Y, Aleman-Muench GR, Lewis G, Chen W, Kang S, Luevanos M, Trudler D, Lipton SA, Soroosh P, Teijaro J, de la Torre JC, Arditi M, Karin M, Sanchez-Lopez E. Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation. Immunity. 2021 Jul 13;54(7):1463-1477.e11. doi: 10.1016/j.immuni.2021.05.004. Epub 2021 Jun 10. PMID: 34115964; PMCID: PMC8189765.
 Supported by the MARC through the Pilot Project Grant program.
JMRI vol 53 issue 3
Editorial for "In Vivo Assessment of Age- and Loading Configuration-Related Changes in Multiscale Mechanical Behavior of the Human Proximal Femur Using MRI-Based Finite Element Analysis"
Bae WC. Editorial for "In Vivo Assessment of Age- and Loading Configuration-Related Changes in Multiscale Mechanical Behavior of the Human Proximal Femur Using MRI-Based Finite Element Analysis". J Magn Reson Imaging. 2021 Mar;53(3):913-914. doi: 10.1002/jmri.27427. Epub 2020 Nov 6. PMID: 33155743.
Skeletal Radiology
Quantitative magnetic resonance imaging of meniscal pathology ex vivo
Bae WC, Tadros AS, Finkenstaedt T, Du J, Statum S, Chung CB. Quantitative magnetic resonance imaging of meniscal pathology ex vivo. Skeletal Radiol. 2021 Dec;50(12):2405-2414. doi: 10.1007/s00256-021-03808-6. Epub 2021 May 13. PMID: 33983499; PMCID: PMC8536602.

EMJ Innovations
Triggers, Timescales, and Treatments for Cytokine-Mediated Tissue Damage
McBride DA, Kerr MD, Dorn NC, Ogbonna DA, Santos EC, Shah NJ. Triggers, Timescales, and Treatments for Cytokine-Mediated Tissue Damage. Euro Med J Innov. 2021 Feb;5(1):52-62. doi: 10.33590/emjinnov/20-00203. Epub 2020 Dec 9. PMID: 34013158; PMCID: PMC8130813.



Supported by the MARC through the Pilot Project Grant program.






 

2020

Skeletal Radiology
MR imaging pattern of tibial subchondral bone structure: considerations of meniscal coverage and integrity
Ariyachaipanich A, Kaya E, Statum S, Biswas R, Tran B, Bae WC, Chung CB. MR imaging pattern of tibial subchondral bone structure: considerations of meniscal coverage and integrity. Skeletal Radiol. 2020 Dec;49(12):2019-2027. doi: 10.1007/s00256-020-03517-6. Epub 2020 Jun 26. PMID: 32591855; PMCID: PMC7658005.

JCI Insight October 2020
PTPN2 links colonic and joint inflammation in experimental autoimmune arthritis
Hsieh WC, Svensson MN, Zoccheddu M, Tremblay ML, Sakaguchi S, Stanford SM, Bottini N. PTPN2 links colonic and joint inflammation in experimental autoimmune arthritis. JCI Insight. 2020 Oct 15;5(20):141868. doi: 10.1172/jci.insight.141868. PMID: 33055428.
Journal of Medicine and Surgical Sciences
A novel bioengineered material to reverse intervertebral disc degeneration
Daisuke Fukui, Koichi Masuda, Michael Zimber, Stephanie Y. Adachi, Natsuko Arimoto, Jeong Ho Kim, … Gail K. Naughton*. A Novel Bioengineered Material to Reverse Intervertebral Disc Degeneration. Journal of Medicine and Surgical Sciences, 2020 May, 2(1), 1–10. http://doi.org/10.5281/zenodo.3777266.


Science Advances June 2020
Synoviocyte-targeted therapy synergizes with TNF inhibition in arthritis reversal
Svensson MND, Zoccheddu M, Yang S, Nygaard G, Secchi C, Doody KM, Slowikowski K, Mizoguchi F, Humby F, Hands R, Santelli E, Sacchetti C, Wakabayashi K, Wu DJ, Barback C, Ai R, Wang W, Sims GP, Mydel P, Kasama T, Boyle DL, Galimi F, Vera D, Tremblay ML, Raychaudhuri S, Brenner MB, Firestein GS, Pitzalis C, Ekwall AH, Stanford SM, Bottini N. Synoviocyte-targeted therapy synergizes with TNF inhibition in arthritis reversal. Sci Adv. 2020 Jun 26;6(26):eaba4353. doi: 10.1126/sciadv.aba4353. PMID: 32637608; PMCID: PMC7319753.

Highlighted in Natural Reviews Rheumatology: Therapies targeting FLS and TNF can have synergistic effects (November 2020)
Biomaterials Science
Characterization of regulatory T cell expansion for manufacturing cellular immunotherapies.
McBride DA, Kerr MD, Wai SL, Yee YY, Ogbonna DA, Shah NJ. Characterization of
regulatory T cell expansion for manufacturing cellular immunotherapies. Biomaterials
science. 2020 May 22. PubMed PMID: 32441280; DOI: 10.1039/d0bm00622j.


Supported by the MARC through the Pilot Project Grant program.
Arthritis and Rheumatology May 2020
Differential DNA Methylation of Networked Signaling, Transcriptional, Innate and Adaptive Immunity, and Osteoclastogenesis Genes and Pathways in Gout
 Wang Z, Zhao Y, Phipps-Green A, Liu-Bryan R, Ceponis A, Boyle DL, Wang J, Merriman TR, Wang W, Terkeltaub R. Differential DNA Methylation of Networked Signaling, Transcriptional, Innate and Adaptive Immunity, and Osteoclastogenesis Genes and Pathways in Gout. Arthritis Rheumatol. 2020 May;72(5):802-814. doi: 10.1002/art.41173. Epub 2020 Mar 23. PMID: 31738005; PMCID: PMC7323903.

Supported by the MARC through the Pilot Project Grant program.
Cells v.9 coverpage
Hypoxia-Inducible Factor-1α: The Master Regulator of Endothelial Cell Senescence in Vascular Aging
Alique M, Sánchez-López E, Bodega G, Giannarelli C, Carracedo J, Ramírez R. Hypoxia-Inducible Factor-1α: The Master Regulator of Endothelial Cell Senescence in Vascular Aging. Cells. 2020 Jan 13;9(1):195. doi: 10.3390/cells9010195. PMID: 31941032; PMCID: PMC7016968. 


Supported by the MARC through the Pilot Project Grant program.


2019

Wires 2019


Applications of Molecular Engineering in T-cell-based Immunotherapies
McBride DA, Kerr MD, Wai SL, Shah NJ. Applications of molecular engineering in T-cell-based immunotherapies. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2019 Sep;11(5):e1557. doi: 10.1002/wnan.1557. Epub 2019 Apr 10. PMID: 30972976; PMCID: PMC7869905.




Investigative Radiology
Ultrashort Time to Echo Magnetic Resonance Evaluation of Calcium Pyrophosphate Crystal Deposition in Human Menisci
Finkenstaedt T, Biswas R, Abeydeera NA, Siriwanarangsun P, Healey R, Statum S, Bae WC, Chung CB. Ultrashort Time to Echo Magnetic Resonance Evaluation of Calcium Pyrophosphate Crystal Deposition in Human Menisci. Invest Radiol. 2019 Jun;54(6):349-355. doi: 10.1097/RLI.0000000000000547. PMID: 30688685; PMCID: PMC6499636.