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Publications

Publications are annotated with the name of the Institute's Center that led the efforts in each case.

  • PreCSN = The Center for Precision Computational Systems Network
  • ConCISE = The Consortium for Cell-Inspired Systems Engineering
  • HUMANOID = Human Organoid Center of Research Excellence (CoRE)

DEPOSITED IN PRE-PRINT SERVER:

  1. GIV/Girdin, a Non-receptor Modulator for Gαi/s, Regulates Spatiotemporal Signaling during Sperm Capacitation and is Required for Male Fertility. Sequoyah Reynoso, Vanessa Castillo, Gajanan Dattatray Katkar, Inmaculada Lopez-Sanchez, Sahar Taheri, Celia R. Espinoza, Cristina Rohena, Debashis Sahoo, Pascal Gagneux, and Pradipta Ghosh. bioRxiv 2021. BIORXIV/2021/442927. - ConCISE and PreCSN

  2. SPT6 loss Permits the Transdifferentiation of Keratinocytes into an Intestinal Fate that Recapitulates Barretts Metaplasia. Daniella Vo, MacKenzie R. Fuller, Courtney Tindle, Mahithashree Anandachar, Soumita Das, Debashis Sahoo, and Pradipta Ghosh. bioRxiv 2021. BIORXIV/2021/442930. - HUMANOID and PreCSN.

  3. Morphological principles of neuronal mitochondriaRachel MendelsohnGuadalupe C. GarciaThomas M. BartolChristopher T. LeeP. KhandelwalEmily LiuDonald J. SpencerAdam HusarEric A. BushongSebastien PhanGuy PerkinsMark H. EllismanAlexander SkupinTerrence J. SejnowskiPadmini Rangamani. bioRxiv 2021.03.15.435547; doi: https://doi.org/10.1101/2021.03.15.435547. - ConCISE

  4. Modeling membrane nanotube morphology: the role of heterogeneity in composition and material propertiesHaleh AlimohamadiBen OvrynPadmini Rangamani. bioRxiv 373811; doi: https://doi.org/10.1101/373811. - ConCISE.

  5. An AI-guided invariant signature places MIS-C with Kawasaki disease in a continuum of host immune responses. Sahoo D, Katkar GD, Shimizu C, Kim J, Khandelwal S, Tremoulet AH, Kanegaye J, Bocchini J, Das S, Burns JC, Ghosh P; Pediatric Emergency Medicine Kawasaki Disease Research Group.bioRxiv. 2021 Apr 12:2021.04.11.439347. doi: 10.1101/2021.04.11.439347. Preprint.PMID: 33880476. - PreCSN and HUMANOID.  

  6. Adult Stem Cell-derived Complete Lung Organoid Models Emulate Lung Disease in COVID-19. Tindle C, Fuller M, Fonseca A, Taheri S, Ibeawuchi SR, Beutler N, Claire A, Castillo V, Hernandez M, Russo H, Duran J, Crotty Alexander LE, Tipps A, Lin G, Thistlethwaite PA, Chattopadhyay R, Rogers TF, Sahoo D, Ghosh P, Das S.bioRxiv. 2020 Oct 18:2020.10.17.344002. doi: 10.1101/2020.10.17.344002. Preprint. PMID: 33106807 - HUMANOID and PreCSN.

  7. Closed Loop Control between Two GTPase Switches makes the Secretory Functions of the Golgi Responsive to Growth FactorsLingxia QiaoI-Chung LoKrishna K. MiddeNicolas AznarAmer Ali Abd El-HafeezInmaculada Lopez-SanchezVijay GuptaMarilyn G. FarquharPadmini RangamaniPradipta Ghosh. bioRxiv 2021.03.18.436048; doi: https://doi.org/10.1101/2021.03.18.436048. - ConCISE.

  8. Curvature-driven feedback on aggregation-diffusion of proteins in lipid bilayersArijit MahapatraDavid SaintillanPadmini Rangamani. bioRxiv 2021.04.02.438263; doi: https://doi.org/10.1101/2021.04.02.438263. ConCISE. 

  9. Biomembranes undergo complex, non-axisymmetric deformations governed by Kirchhoff-Love kinematics and revealed by a three dimensional computational frameworkDebabrata AuddyaXiaoxuan ZhangRahul GulatiRitvik VasanKrishna GarikipatiPadmini RangamaniShiva Rudraraju. bioRxiv 2021.01.28.428578; doi: https://doi.org/10.1101/2021.01.28.428578. - ConCISE. 

  10. Nanoscale organization of Actin Filaments in the Red Blood Cell Membrane SkeletonRoberta B. NowakHaleh AlimohamadiKersi PestonjamaspPadmini RangamaniVelia M. Fowler. bioRxiv 2021.03.07.434292; doi: https://doi.org/10.1101/2021.03.07.434292. -ConCISE. 

  11. Rapid community-driven development of a SARS-CoV-2 tissue simulator. Wang Y, An G, Becker A, Cockrell C, Collier N, Craig M, Davis CL, Faeder J, Versypt ANF, Gianlupi JF, Glazier JA, Heiland R, Hillen T, Islam MA, Jenner A, Liu B, Morel PA, Narayanan A, Ozik J, Rangamani P, Shoemaker JE, Smith AM, Macklin P bioRxiv. 2020 Apr 5:2020.04.02.019075. doi: 10.1101/2020.04.02.019075. Preprint.PMID: 32511322. - ConCISE 


ACCEPTED, IN PRESS:

  1. AI-guided Discovery of a Barrier-Protective Therapy in Inflammatory Bowel Disease. Sahoo, D*, Swanson L, Sayed, I, Katkar G.D., Ibeawuchi S., Mittal Y., Pranadinata RF, Tindle C, Fuller MR, Stec DL, Chang JT, Sandborn WJ, Das S*, Ghosh*, P. Nat Commun (Accepted, In Press, May 2021). - PreCSN and HUMANOID.

  2. AI-guided discovery of the invariant host response to viral pandemics. Sahoo D, Katkar GD, Khandelwal S, Behroozikhah M, Claire A, Castillo V, Tindle C, Fuller M, Taheri S, Rogers TF, Beutler N, Ramirez SI, Rawlings SA, Pretorius V, Smith DM, Burton DR, Crotty Alexander LE, Duran J, Crotty S, Dan JM, Das S, Ghosh P.bioRxiv. 2020 Sep 22:2020.09.21.305698. doi: 10.1101/2020.09.21.305698. Preprint.PMID: 32995790  - PreCSN and HUMANOID [ Accepted eBioMedicine, May 2021]. 

  3. Transfer function for YAP/TAZ nuclear translocation revealed through spatial systems modelingKiersten E. ScottStephanie I. FraleyPadmini Rangamani. bioRxiv 2020.10.14.340349; doi: https://doi.org/10.1101/2020.10.14.340349 [Accepted, PNAS]

  4. Drug repurposing screens identify chemical entities for the development of COVID-19 interventions. Malina Bakowski, Nathan Beutler , Dr Karen Wolff , Melanie Kirkpatrick , Emily Chen , Tu-Trinh Nguyen , Dr Laura Riva , Dr Namir Shaabani , Mara Parren , James Ricketts , Dr Anil Gupta , Kastin Pan , Peiting Kuo , Mackenzie Fuller , Elijah Garcia , Dr John Teijaro , Linlin Yang , Dr Debashis Sahoo , Victor Chi , Edward Huang , Natalia Vargas , Dr Amanda Roberts , Dr Soumita Das , Professor Pradipta Ghosh , Dr Ashley Woods , Dr Sean Joseph , Dr Peter Schultz , Dr Dennis Burton , Dr Arnab Chatterjee , Dr Case McNamara , Dr Thomas Rogers , Mr Mitchell Hull. [Accepted, Apr, 2021, Nat Comm]. - PreCSN and HUMANOID

  5. Building Unconventional G-protein Coupled Receptors: One block at a time. Ghosh, Pradipta and Mullick, Madhubanti. Accepted, In Press. Trends in Pharmacological Sciences, May 2021. -ConCISE.

PUBLISHED: Peer-Reviewed Original Articles

  1. Immunosuppression of Macrophages Underlies the Cardioprotective Effects of CST (Catestatin). Ying W, Tang K, Avolio E, Schilling JM, Pasqua T, Liu MA, Cheng H, Gao H, Zhang J, Mahata S, Ko MS, Bandyopadhyay G, Das S, Roth DM, Sahoo D, Webster NJG, Sheikh F, Ghosh G, Patel HH, Ghosh P, van den Bogaart G, Mahata SK.Hypertension. 2021 May 5;77(5):1670-1682. doi: 10.1161/HYPERTENSIONAHA.120.16809. Epub 2021 Apr 7.PMID: 33826401 - PreCSN.

  2. Chromogranin A regulates gut permeability via the antagonistic actions of its proteolytic peptides. Muntjewerff EM, Tang K, Lutter L, Christoffersson G, Nicolasen MJT, Gao H, Katkar GD, Das S, Ter Beest M, Ying W, Ghosh P, Aidy SE, Oldenburg B, van den Bogaart G, Mahata SK.Acta Physiol (Oxf). 2021 Mar 30:e13655. doi: 10.1111/apha.13655. Online ahead of print.PMID: 33783968. 

  3. Discovery of antiproliferative and anti-FAK inhibitory activity of 1,2,4-triazole derivatives containing acetamido carboxylic acid skeleton. Mustafa M, Abuo-Rahma GEA, Abd El-Hafeez AA, Ahmed ER, Abdelhamid D, Ghosh P, Hayallah AM.Bioorg Med Chem Lett. 2021 May 15;40:127965. doi: 10.1016/j.bmcl.2021.127965. Epub 2021 Mar 17.PMID: 33744442. - Drug Discovery Program

  4. Deletion of intestinal epithelial AMP-activated protein kinase alters distal colon permeability but not glucose homeostasis. Olivier S, Pochard C, Diounou H, Castillo V, Divoux J, Alcantara J, Leclerc J, Guilmeau S, Huet C, Charifi W, Varin TV, Daniel N, Foretz M, Neunlist M, Salomon BL, Ghosh P, Marette A, Rolli-Derkinderen M, Viollet B.Mol Metab. 2021 May;47:101183. doi: 10.1016/j.molmet.2021.101183. Epub 2021 Feb 4.PMID: 33548500.  

  5. Value of models for membrane budding. Lee CT, Akamatsu M, Rangamani P. Curr Opin Cell Biol. 2021 Mar 8;71:38-45. doi: 10.1016/j.ceb.2021.01.011. Online ahead of print.PMID: 33706232- ConCISE 

  6. Isolation and characterization of hESC-derived heart field-specific cardiomyocytes unravels new insights into their transcriptional and electrophysiological profiles. Pezhouman A, Engel JL, Nguyen NB, Skelton RJP, Gilmore WB, Qiao R, Sahoo D, Zhao P, Elliott DA, Ardehali R.Cardiovasc Res. 2021 Mar 21:cvab102. doi: 10.1093/cvr/cvab102. Online ahead of print.PMID: 33744937. - PreCSN


  7. Membrane bending by protein phase separation. Yuan F, Alimohamadi H, Bakka B, Trementozzi AN, Day KJ, Fawzi NL, Rangamani P, Stachowiak JC. Proc Natl Acad Sci U S A. 2021 Mar 16;118(11):e2017435118. doi: 10.1073/pnas.2017435118. PMID: 33688043- ConCISE.

  8. SPT6 promotes epidermal differentiation and blockade of an intestinal-like phenotype through control of transcriptional elongation. Li J, Xu X, Tiwari M, Chen Y, Fuller M, Bansal V, Tamayo P, Das S, Ghosh P, Sen GL.Nat Commun. 2021 Feb 4;12(1):784. doi: 10.1038/s41467-021-21067-w.PMID: 33542242. - HUMANOID 

  9. Apurinic/Apyrimidinic Endonuclease 1 Restricts the Internalization of Bacteria Into Human Intestinal Epithelial Cells Through the Inhibition of Rac1. den Hartog G, Butcher LD, Ablack AL, Pace LA, Ablack JNG, Xiong R, Das S, Stappenbeck TS, Eckmann L, Ernst PB, Crowe SE.Front Immunol. 2021 Feb 2;11:553994. doi: 10.3389/fimmu.2020.553994. eCollection 2020. PMID: 33603730. - HUMANOID

  10. A zebrafish model of granulin deficiency reveals essential roles in myeloid cell differentiation. Campbell CA, Fursova O, Cheng X, Snella E, McCune A, Li L, Solchenberger B, Schmid B, Sahoo D, Morton M, Traver D, Espín-Palazón R.Blood Adv. 2021 Feb 9;5(3):796-811. doi: 10.1182/bloodadvances.2020003096.PMID: 33560393. -PreCSN

  11. Stability Analysis of a Signaling Circuit with Dual Species of GTPase Switches. Stolerman LM, Ghosh P, Rangamani P. Bull Math Biol. 2021 Feb 20;83(4):34. doi: 10.1007/s11538-021-00864-w. PMID: 33609194 - ConCISE.

  12. Boolean implication analysis unveils candidate universal relationships in microbiome data. Vo D, Singh SC, Safa S, Sahoo D.BMC Bioinformatics. 2021 Feb 5;22(1):49. doi: 10.1186/s12859-020-03941-4.PMID: 33546590. PreCSN. 

  13. Computational modeling approaches to cAMP/PKA signaling in cardiomyocytes. McCabe KJ, Rangamani P.J Mol Cell Cardiol. 2021 May;154:32-40. doi: 10.1016/j.yjmcc.2021.01.008. Epub 2021 Feb 4.PMID: 33548239 -ConCISE. 

  14. E-cigarettes compromise the gut barrier and trigger inflammation. Sharma A, Lee J, Fonseca AG, Moshensky A, Kothari T, Sayed IM, Ibeawuchi SR, Pranadinata RF, Ear J, Sahoo D, Crotty-Alexander LE, Ghosh P, Das S.iScience. 2021 Jan 6;24(2):102035. doi: 10.1016/j.isci.2021.102035. eCollection 2021 Feb 19.PMID: 33537654. - HUMANOID

  15. The Mechanics and Thermodynamics of Tubule Formation in Biological Membranes. Mahapatra A, Uysalel C, Rangamani P. J Membr Biol. 2021 Jan 19. doi: 10.1007/s00232-020-00164-9. Online ahead of print. PMID: 33462667 -ConCISE.
  16. Spatially compartmentalized phase regulation of a Ca2+-cAMP-PKA oscillatory circuit. Tenner B, Getz M, Ross B, Ohadi D, Bohrer CH, Greenwald E, Mehta S, Xiao J, Rangamani P, Zhang J.Elife. 2020 Nov 17;9:e55013. doi: 10.7554/eLife.55013.PMID: 33201801 -ConCISE

  17. Receptor tyrosine kinases activate heterotrimeric G proteins via phosphorylation within the interdomain cleft of Gαi. Kalogriopoulos NA, Lopez-Sanchez I, Lin C, Ngo T, Midde KK, Roy S, Aznar N, Murray F, Garcia-Marcos M, Kufareva I, Ghassemian M, Ghosh P.Proc Natl Acad Sci U S A. 2020 Nov 17;117(46):28763-28774. doi: 10.1073/pnas.2004699117. Epub 2020 Nov 2.PMID: 33139573 - ConCISE

  18. TLR4 signaling and macrophage inflammatory responses are dampened by GIV/Girdin. Swanson L, Katkar GD, Tam J, Pranadinata RF, Chareddy Y, Coates J, Anandachar MS, Castillo V, Olson J, Nizet V, Kufareva I, Das S, Ghosh P.Proc Natl Acad Sci U S A. 2020 Oct 27;117(43):26895-26906. doi: 10.1073/pnas.2011667117. Epub 2020 Oct 14.PMID: 33055214. - ConCISE.

  19. ATP synthase: Evolution, energetics, and membrane interactions. Nirody JA, Budin I, Rangamani P.J Gen Physiol. 2020 Nov 2;152(11):e201912475. doi: 10.1085/jgp.201912475. PMID: 32966553. - ConCISE

  20. Haematopoietic stem cell-dependent Notch transcription is mediated by p53 through the Histone chaperone Supt16h. Espanola SG, Song H, Ryu E, Saxena A, Kim ES, Manegold JE, Nasamran CA, Sahoo D, Oh CK, Bickers C, Shin U, Grainger S, Park YH, Pandolfo L, Kang MS, Kang S, Myung K, Cooper KL, Yelon D, Traver D, Lee Y. Nat Cell Biol. 2020 Dec;22(12):1411-1422. doi: 10.1038/s41556-020-00604-7. Epub 2020 Nov 23. PMID: 33230303 - PreCSN.

  21. Diffuso-kinetic membrane budding dynamics. Rojas Molina R , Liese S , Alimohamadi H , Rangamani P , Carlson A . Soft Matter. 2020 Dec 28;16(48):10889-10899. doi: 10.1039/d0sm01028f. Epub 2020 Oct 30. PMID: 33125025. - ConCISE.

  22. The DNA Glycosylase NEIL2 Suppresses Fusobacterium-Infection-Induced Inflammation and DNA Damage in Colonic Epithelial Cells. Sayed IM, Chakraborty A, Abd El-Hafeez AA, Sharma A, Sahan AZ, Huang WJM, Sahoo D, Ghosh P, Hazra TK, Das S.Cells. 2020 Aug 28;9(9):1980. doi: 10.3390/cells9091980.PMID: 32872214 - HUMANOID

  23. DDX5 promotes oncogene C3 and FABP1 expressions and drives intestinal inflammation and tumorigenesis. Abbasi N, Long T, Li Y, Yee BA, Cho BS, Hernandez JE, Ma E, Patel PR, Sahoo D, Sayed IM, Varki N, Das S, Ghosh P, Yeo GW, Huang WJM.Life Sci Alliance. 2020 Aug 18;3(10):e202000772. doi: 10.26508/lsa.202000772. Print 2020 Oct.PMID: 32817263 - HUMANOID and PreCSN 

  24. Potentiation of calcium-activated chloride secretion and barrier dysfunction may underlie EGF receptor tyrosine kinase inhibitor-induced diarrhea. Kim Y, Quach A, Das S, Barrett KE. Physiol Rep. 2020 Jul;8(13):e14490. doi: 10.14814/phy2.14490.PMID: 32652816 - HUMANOID
  25. Primary Female Urethral Carcinoma: Proposed Staging Modifications Based on Assessment of Female Urethral Histology and Analysis of a Large Series of Female Urethral Carcinomas. Aron M, Park S, Lowenthal BM, Gupta S, Sahoo D, Cheville JC, Hansel DE. Am J Surg Pathol. 2020 Aug 28. doi: 10.1097/PAS.0000000000001569. Online ahead of print.PMID: 32868524 - PreCSN
  26. Upregulation of CD47 Is a Host Checkpoint Response to Pathogen Recognition. Tal MC, Torrez Dulgeroff LB, Myers L, Cham LB, Mayer-Barber KD, Bohrer AC, Castro E, Yiu YY, Lopez Angel C, Pham E, Carmody AB, Messer RJ, Gars E, Kortmann J, Markovic M, Hasenkrug M, Peterson KE, Winkler CW, Woods TA, Hansen P, Galloway S, Wagh D, Fram BJ, Nguyen T, Corey D, Kalluru RS, Banaei N, Rajadas J, Monack DM, Ahmed A, Sahoo D, Davis MM, Glenn JS, Adomati T, Lang KS, Weissman IL, Hasenkrug KJ. mBio. 2020 Jun 23;11(3):e01293-20. doi: 10.1128/mBio.01293-20.PMID: 32576678. - PreCSN  

  27. Non-uniform distribution of myosin-mediated forces governs red blood cell membrane curvature through tension modulation. Alimohamadi H, Smith AS, Nowak RB, Fowler VM, Rangamani P. PLoS Comput Biol. 2020 May 26;16(5):e1007890. doi: 10.1371/journal.pcbi.1007890. eCollection 2020 May.PMID: 32453720. - ConCISE
  28. Phase Separation of a PKA Regulatory Subunit Controls cAMP Compartmentation and Oncogenic Signaling. Zhang JZ, Lu TW, Stolerman LM, Tenner B, Yang JR, Zhang JF, Falcke M, Rangamani P, Taylor SS, Mehta S, Zhang J. Cell. 2020 Aug 20:S0092-8674(20)30991-0. doi: 10.1016/j.cell.2020.07.043. Online ahead of print.PMID: 32846158. - ConCISE
  29. Interactions between calmodulin and neurogranin govern the dynamics of CaMKII as a leaky integrator. Ordyan M, Bartol T, Kennedy M, Rangamani P, Sejnowski T. PLoS Comput Biol. 2020 Jul 17;16(7):e1008015. doi: 10.1371/journal.pcbi.1008015. eCollection 2020 Jul.PMID: 32678848  - ConCISE
  30. GIV/Girdin and Exo70 Collaboratively Regulate the Mammalian Polarized Exocytic Machinery. Rohena C, Rajapakse N, Lo IC, Novick P, Sahoo D, Ghosh P. iScience. 2020 Jul 24;23(7):101246. doi: 10.1016/j.isci.2020.101246. Epub 2020 Jun 7. PMID: 32590327 - ConCISE
  31. GIV•Kindlin Interaction Is Required for Kindlin-Mediated Integrin Recognition and Activation. Rohena C, Kalogriopoulos N, Rajapakse N, Roy S, Lopez-Sanchez I, Ablack J, Sahoo D, Ghosh P. iScience. 2020 Jun 26;23(6):101209. doi: 10.1016/j.isci.2020.101209. Epub 2020 May 28. PMID: 32535026 - ConCISE
  32. Transcriptional profiling of lung macrophages identifies a predictive signature for inflammatory lung disease in preterm infants. Sahoo D, Zaramela LS, Hernandez GE, Mai U, Taheri S, Dang D, Stouch AN, Medal RM, McCoy AM, Aschner JL, Blackwell TS, Zengler K, Prince LS. Commun Biol. 2020 May 22;3(1):259. doi: 10.1038/s42003-020-0985-2.PMID: 32444859 - PreCSN
  33. Helicobacter pylori infection downregulates the DNA glycosylase NEIL2, resulting in increased genome damage and inflammation in gastric epithelial cells. Sayed IM, Sahan AZ, Venkova T, Chakraborty A, Mukhopadhyay D, Bimczok D, Beswick EJ, Reyes VE, Pinchuk I, Sahoo D, Ghosh P, Hazra TK, Das S. J Biol Chem. 2020 Aug 7;295(32):11082-11098. doi: 10.1074/jbc.RA119.009981. Epub 2020 Jun 9. PMID: 32518160 - HUMANOID
  34. Enhanced mitochondrial fission suppresses signaling and metastasis in triple-negative breast cancer. Humphries BA, Cutter AC, Buschhaus JM, Chen YC, Qyli T, Palagama DSW, Eckley S, Robison TH, Bevoor A, Chiang B, Haley HR, Sahoo S, Spinosa PC, Neale DB, Boppisetti J, Sahoo D, Ghosh P, Lahann J, Ross BD, Yoon E, Luker KE, Luker GD. Breast Cancer Res. 2020 Jun 5;22(1):60. doi: 10.1186/s13058-020-01301-x. PMID: 32503622 - PreCSN
  35. Regulating cellular cyclic adenosine monophosphate: "Sources," "sinks," and now, "tunable valves". Getz M, Rangamani P, Ghosh P. Wiley Interdiscip Rev Syst Biol Med. 2020 Apr 23:e1490. doi: 10.1002/wsbm.1490. Online ahead of print.PMID: 32323924 - ConCISE 
  36. Lee CT, Laughlin JG, Angliviel de La Beaumelle N, Amaro RE, McCammon JA, Ramamoorthi R, Holst M, Rangamani P. 3D mesh processing using GAMer 2 to enable reaction-diffusion simulations in realistic cellular geometries. PLoS Comput Biol. 2020 Apr 6;16(4):e1007756. doi: 10.1371/journal.pcbi.1007756. eCollection 2020 Apr.PMID: 32251448 - ConCISE
  37. Das B, Okamoto K, Rabalais J, Marchelletta RR, Barrett KE, Das S, Niwa M, Sivagnanam M. Congenital Tufting Enteropathy-Associated Mutant of Epithelial Cell Adhesion Molecule Activates the Unfolded Protein Response in a Murine Model of the Disease. Cells. 2020 Apr 11;9(4):946. doi: 10.3390/cells9040946.PMID: 32290509 - HUMANOID
  38. Lee CT, Laughlin JG, Moody JB, Amaro RE, McCammon JA, Holst M, Rangamani P. An Open-Source Mesh Generation Platform for Biophysical Modeling Using Realistic Cellular Geometries. Biophys J. 2020 Mar 10;118(5):1003-1008. doi: 10.1016/j.bpj.2019.11.3400. Epub 2020 Jan 22.PMID: 32032503 - ConCISE
  39. Stolerman LM, Getz M, Smith SGL, Holst M, Rangamani P. Stability Analysis of a Bulk-Surface Reaction Model for Membrane Protein Clustering. Bull Math Biol. 2020 Feb 6;82(2):30. doi: 10.1007/s11538-020-00703-4.PMID: 32025918 - ConCISE
  40. Computational Approach to Identifying Universal Macrophage Biomarkers. Dang D, Taheri S, Das S, Ghosh P, Prince LS, Sahoo D. Front Physiol. 2020 Apr 8;11:275. doi: 10.3389/fphys.2020.00275. eCollection 2020.PMID: 32322218 - PreCSN 
  41. Pearce KM, Bell M, Linthicum WH, Wen Q, Srinivasan J, Rangamani P, Scarlata S. Gαq-mediated calcium dynamics and membrane tension modulate neurite plasticity. Mol Biol Cell. 2020 Mar 19;31(7):683-694. doi: 10.1091/mbc.E19-09-0536. Epub 2019 Dec 11.PMID: 31825720 - ConCISE
  42. The stress polarity signaling (SPS) pathway serves as a marker and a target in the leaky gut barrier: implications in aging and cancer. Ghosh P, Swanson L, Sayed IM, Mittal Y, Lim BB, Ibeawuchi SR, Foretz M, Viollet B, Sahoo D, Das S. Life Sci Alliance. 2020 Feb 10;3(3):e201900481. doi: 10.26508/lsa.201900481. Print 2020 Mar. PMID: 32041849 - HUMANOID
  43. Alimohamadi H, Ovryn B, Rangamani P. Modeling membrane nanotube morphology: the role of heterogeneity in composition and material properties. Sci Rep. 2020 Feb 13;10(1):2527. doi: 10.1038/s41598-020-59221-x.PMID: 32054874. - ConCISE
  44. Host engulfment pathway controls inflammation in inflammatory bowel disease. Sayed IM, Suarez K, Lim E, Singh S, Pereira M, Ibeawuchi SR, Katkar G, Dunkel Y, Mittal Y, Chattopadhyay R, Guma M, Boland BS, Dulai PS, Sandborn WJ, Ghosh P, Das S. FEBS J. 2020 Jan 30:10.1111/febs.15236. doi: 10.1111/febs.15236. Online ahead of print. PMID: 32003126 - HUMANOID
  45. Akamatsu M, Vasan R, Serwas D, Ferrin MA, Rangamani P, Drubin DG. Principles of self-organization and load adaptation by the actin cytoskeleton during clathrin-mediated endocytosis. Elife. 2020 Jan 17;9:e49840. doi: 10.7554/eLife.49840.PMID: 31951196. - ConCISE
  46. Lowenthal BM, Sahoo D, Amin MB, Hansel DE. Urothelial Proliferation of Unknown Malignant Potential Involving the Bladder: Histopathologic Features and Risk of Progression in De Novo Cases and Cases With Prior Neoplasia. Arch Pathol Lab Med. 2019 Dec 11. doi: 10.5858/arpa.2019-0005-OA. Online ahead of print. PMID: 31825667 - PreCSN
  47. Ohadi D, Schmitt DL, Calabrese B, Halpain S, Zhang J, Rangamani P. Computational Modeling Reveals Frequency Modulation of Calcium-cAMP/PKA Pathway in Dendritic Spines. Biophys J. 2019 Nov 19;117(10):1963-1980. doi: 10.1016/j.bpj.2019.10.003. Epub 2019 Oct 9.PMID: 31668749. - ConCISE
  48. Wong J, Garcia-Carbonell R, Zelic M, Ho SB, Boland BS, Yao SJ, Desai SA, Das S, Planell N, Harris PA, Font-Burgada J, Taniguchi K, Bertin J, Salas A, Pasparakis M, Gough PJ, Kelliher M, Karin M, Guma M. RIPK1 Mediates TNF-Induced Intestinal Crypt Apoptosis During Chronic NF-κB Activation. Cell Mol Gastroenterol Hepatol. 2020;9(2):295-312. doi: 10.1016/j.jcmgh.2019.10.002. Epub 2019 Oct 10.PMID: 31606566 - HUMANOID
  49. Mukohyama J, Isobe T, Hu Q, Hayashi T, Watanabe T, Maeda M, Yanagi H, Qian X, Yamashita K, Minami H, Mimori K, Sahoo D, Kakeji Y, Suzuki A, Dalerba P, Shimono Y. miR-221 Targets QKI to Enhance the Tumorigenic Capacity of Human Colorectal Cancer Stem Cells. Cancer Res. 2019 Oct 15;79(20):5151-5158. doi: 10.1158/0008-5472.CAN-18-3544. Epub 2019 Aug 15.PMID: 31416845. - PreCSN
  50. Das B, Okamoto K, Rabalais J, Kozan PA, Marchelletta RR, McGeough MD, Durali N, Go M, Barrett KE, Das S, Sivagnanam M. Enteroids expressing a disease-associated mutant of EpCAM are a model for congenital tufting enteropathy. Am J Physiol Gastrointest Liver Physiol. 2019 Nov 1;317(5):G580-G591. doi: 10.1152/ajpgi.00098.2019. Epub 2019 Aug 21.PMID: 31433211 - HUMANOID
  51. Structural basis for GPCR-independent activation of heterotrimeric Gi proteins. Kalogriopoulos NA, Rees SD, Ngo T, Kopcho NJ, Ilatovskiy AV, Sun N, Komives EA, Chang G, Ghosh P, Kufareva I. Proc Natl Acad Sci U S A. 2019 Aug 13;116(33):16394-16403. doi: 10.1073/pnas.1906658116. Epub 2019 Jul 30. PMID: 31363053 - ConCISE
  52. Dabydeen SA, Desai A, Sahoo D. Unbiased Boolean analysis of public gene expression data for cell cycle gene identification. Mol Biol Cell. 2019 Jul 1;30(14):1770-1779. doi: 10.1091/mbc.E19-01-0013. Epub 2019 May 15.PMID: 31091168. - PreCSN
  53. Garcia-Carbonell R, Yao SJ, Das S, Guma M. Dysregulation of Intestinal Epithelial Cell RIPK Pathways Promotes Chronic Inflammation in the IBD Gut. Front Immunol. 2019 May 20;10:1094. doi: 10.3389/fimmu.2019.01094. eCollection 2019.PMID: 31164887 - HUMANOID
  54. Rajasekaran S, Nagarajha Selvan LD, Dotts K, Kumar R, Rishi P, Khetan V, Bisht M, Sivaraman K, Krishnakumar S, Sahoo D, Campbell MJ, Elchuri SV, Miles WO. Non-coding and Coding Transcriptional Profiles Are Significantly Altered in Pediatric Retinoblastoma Tumors. Front Oncol. 2019 Apr 16;9:221. doi: 10.3389/fonc.2019.00221. eCollection 2019.PMID: 31058073. - PreCSN
  55. Stobdan T, Sahoo D, Azad P, Hartley I, Heinrichsen E, Zhou D, Haddad GG. High fat diet induces sex-specific differential gene expression in Drosophila melanogaster. PLoS One. 2019 Mar 12;14(3):e0213474. doi: 10.1371/journal.pone.0213474. eCollection 2019.PMID: 30861021 - PreCSN
  56. Rubinstein MR, Baik JE, Lagana SM, Han RP, Raab WJ, Sahoo D, Dalerba P, Wang TC, Han YW. Fusobacterium nucleatum promotes colorectal cancer by inducing Wnt/β-catenin modulator Annexin A1. EMBO Rep. 2019 Apr;20(4):e47638. doi: 10.15252/embr.201847638. Epub 2019 Mar 4.PMID: 30833345. - PreCSN
  57. A predictive computational model reveals that GIV/girdin serves as a tunable valve for EGFR-stimulated cyclic AMP signals. Getz M, Swanson L, Sahoo D, Ghosh P, Rangamani P. Mol Biol Cell. 2019 Jun 15;30(13):1621-1633. doi: 10.1091/mbc.E18-10-0630. Epub 2019 Apr 24. PMID: 31017840 - ConCISE
  58. Near-Infrared Light-Activated DNA-Agonist Nanodevice for Nongenetically and Remotely Controlled Cellular Signaling and Behaviors in Live Animals. Wang M, He F, Li H, Yang S, Zhang J, Ghosh P, Wang HH, Nie Z. Nano Lett. 2019 Apr 10;19(4):2603-2613. doi: 10.1021/acs.nanolett.9b00421. Epub 2019 Mar 28. PMID: 30907088 - ConCISE
  59. Kahn SA, Wang X, Nitta RT, Gholamin S, Theruvath J, Hutter G, Azad TD, Wadi L, Bolin S, Ramaswamy V, Esparza R, Liu KW, Edwards M, Swartling FJ, Sahoo D, Li G, Wechsler-Reya RJ, Reimand J, Cho YJ, Taylor MD, Weissman IL, Mitra SS, Cheshier SH. Notch1 regulates the initiation of metastasis and self-renewal of Group 3 medulloblastoma. Nat Commun. 2018 Oct 8;9(1):4121. doi: 10.1038/s41467-018-06564-9.PMID: 30297829. - PreCSN
  60. Chan CKF, Gulati GS, Sinha R, Tompkins JV, Lopez M, Carter AC, Ransom RC, Reinisch A, Wearda T, Murphy M, Brewer RE, Koepke LS, Marecic O, Manjunath A, Seo EY, Leavitt T, Lu WJ, Nguyen A, Conley SD, Salhotra A, Ambrosi TH, Borrelli MR, Siebel T, Chan K, Schallmoser K, Seita J, Sahoo D, Goodnough H, Bishop J, Gardner M, Majeti R, Wan DC, Goodman S, Weissman IL, Chang HY, Longaker MT. Identification of the Human Skeletal Stem Cell. Cell. 2018 Sep 20;175(1):43-56.e21. doi: 10.1016/j.cell.2018.07.029.PMID: 30241615. - PreCSN
  61. Garcia-Carbonell R, Wong J, Kim JY, Close LA, Boland BS, Wong TL, Harris PA, Ho SB, Das S, Ernst PB, Sasik R, Sandborn WJ, Bertin J, Gough PJ, Chang JT, Kelliher M, Boone D, Guma M, Karin M. Elevated A20 promotes TNF-induced and RIPK1-dependent intestinal epithelial cell death. Proc Natl Acad Sci U S A. 2018 Sep 25;115(39):E9192-E9200. doi: 10.1073/pnas.1810584115. Epub 2018 Sep 12.PMID: 30209212. - HUMANOID
  62. Das S, Jayaratne R, Barrett KE. The Role of Ion Transporters in the Pathophysiology of Infectious Diarrhea. Cell Mol Gastroenterol Hepatol. 2018 Mar 5;6(1):33-45. doi: 10.1016/j.jcmgh.2018.02.009. eCollection 2018.PMID: 29928670. - HUMANOID