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Dr. Bruce Zuraw

Dr. Zuraw

Dr. Zuraw  is the Division Chief of the Division of Rheumatology, Allergy and Immunology in the Department of Medicine, UC San Diego. He is the Director of the Section of Allergy and Immunology at the Veterans Affairs San Diego Healthcare System and head of the Allergy & Immunology section of the Division of Rheumatology, Allergy & Immunology at UC San Diego.
Dr. Zuraw is also inaugural holder of the US Hereditary Angioedema Association (HAEA) Endowed Chair.

About the Lab

The Zuraw lab conducts research in two separate areas, angioedema and asthma. Angioedema studies are focused on bradykinin-mediated swelling, investigating genetic determinants of angioedema severity, the role of bradykinin receptors in swelling, and the cell biology of C1 inhibitor deficiency. In collaboration with the US HAEA Angioedema Center, of which Dr. Zuraw is Director, the laboratory is studying improved assays for the diagnosis of angioedema. Asthma studies focus on the role of the airway epithelial cell in inflammatory airway disease.  The laboratory is studying the impact of glucocorticoid-induced leucine zipper (GILZ) in down-regulating airway inflammation as well as the role of B2 and B1 bradykinin receptors as well as transient receptor potential channels in allergic airway inflammation.

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Research Highlights

  1. Establishment of the US HAEA Angioedema Center at UCSD, slated to open in the Spring of 2014.
  2. Hereditary angioedema with normal C1 inhibitor function: consensus of an international expert panel.  Allergy Asthma Proc. 33:S145, 2012.
  3. Corticosteroid-induced gene expression in allergen-challenged asthmatic subjects taking inhaled budesonide. Br. J. Pharmacol. 165:1737, 2012.
  4. Supported by grants from the NIH, DOD, and VA.