Research

Research Highlights
1.    Recent Publication
Dr. Broide’s lab demonstrated the importance of ORMDL3 to asthma

Karta MR, Rosenthal PS, Beppu A, Vuong CY, Miller M, Das S, Kurten RC, Doherty TA, Broide DH. β2 integrins rather than β1 integrins mediate Alternaria-induced group 2 innate lymphoid cell trafficking to the lung. J Allergy Clin Immunol. 2017 Mar 30

Miller M, Tam AB, Mueller JL, Rosenthal P, Beppu A, Gordillo R, McGeough MD, Vuong C, Doherty TA, Hoffman HM, Niwa M, Broide DH. Cutting Edge: Targeting Epithelial ORMDL3 Increases, Rather than Reduces, Airway Responsiveness and Is Associated with Increased Sphingosine-1-Phosphate. J Immunol. 2017 Apr 15;198(8):3017-3022

Miller M, Tam AB, Cho JY, Doherty TA, Pham A, Khorram N, Rosenthal P, Mueller JL, Hoffman HM, Suzukawa M, Niwa M, Broide DH. ORMDL3 is an inducible lung epithelial gene regulating metalloproteases, chemokines, OAS, and ATF6. Proc Natl Acad Sci U S A.  109:16648-53 (2012).

2.    NIH Research Grant Support
Dr. Broide is PI on the following NIH grants:
NIH MERIT AWARD: Eosinophil tissue trafficking (2011-2016)
NIH RO1: Chromosome 17q, allergic inflammation, and remodeling (2013-2018)
NIH Asthma and Allergic Disease Center: Airway inflammation and airway remodeling (2011-2016)

3.    NIH T32 Training Grant
Dr. Broide is PI of an NIH T32 training grant
NIH T32: Training in Molecular and Cell Biology of Allergy (2009-2014)

4.    Mentorship
Dr. Broide is sponsor of an NIH KO8 award to Taylor Doherty MD an Assistant Professor of Medicine at the University of California San Diego

5.    Publications from Dr. Broide Lab
See full list of publications from PubMed