NIH Basic Terms

This section of the NIH application allows up for a maximum of 10 PDF attachments. The Appendix is not to be used to circumvent page limits of the Research Strategy or any other section of the application for which a page limit applies.

Please see the following NIH Notice for guidance on information that may be including in the Appendix of an application: NOT-OD-07-018 .

A formalized agreement whereby a research project is carried out by the grantee with one or more other organizations that are separate legal entities. The grantee, as the direct and primary recipient of a grant funds, is accountable for the performance of the project, the appropriate expenditure of grant funds by all parties, and all other obligations of the grantee, as specified in the NIHGPS. In general, the requirements that apply to the grantee flow down to the consortium participant(s). The grantee is responsible for including the applicable requirements of the NIHGPS in its agreements with collaborating organizations.

The award will be made to a single grantee with a single PI (or as the Contact PI if the award is a MPI award), even though one or more organizations other than the grantee will carry out portions of the planned programmatic activity. The grantee must perform a substantive role in the conduct of the planned research and not merely serve as a conduit of funds to another party or parties.

Find more information on Outgoing Subawards and UC San Diego's Process, click here.

NIH has implemented policy and procedures to allow appointed members of NIH Review and Advisory Groups and peer reviewers with recent substantial service (six times in 18 months), to submit their research grant applications on a continuous basis and to have those applications undergo initial peer review in a timely manner. The continuous submission  policy is limited to NIH R01, R21, and R34 applications that would normally be received on standard submission dates. Continuous submission is NOT available for applications submitted for special dates. Please see NOT-OD-11-093 for additional information. Please check the following NIH website to see if your PD/PI is eligible for continuous submission.

Temporary or ad hoc reviewers who are not eligible for continuous submission are eligible for the late submission window. See NOT-OD-11-035.

A notice of grand funding opportunity. Funding opportunities include a description of the opportunity as well as information on award and award administration, eligibility, application and submission instructions, application review, agency contacts, and other information regarding the funding opportunity.

Funding opportunity announcements may be known as program announcements, requests for applications, notices of funding availability, solicitations, or other names depending on the agency and type of program. Notice of Funding Opportunities can be found at Grants.gov/Find and in the NIH Guide for Grants and Contracts. In addition, NIH and other HHS Agencies have developed omnibus Parent Announcements for common grant mechanisms that have transitioned to electronic submission, for use by applicants who wish to submit what were formerly termed "unsolicited" or "investigator-initiated" applications.

At UC San Diego, it is very important for your Sponsored Projects Office (SPO) Analyst to know what it is you are applying to, especially if UCSD is a consortium/subaward. The SPO will use the Notice of Funding Opportunity (NOFO) to better support your application. To find the Officer/Analyst assigned to the agreement visit the Research Administration Activity Dashboard.

Should be treated the same as domestic consortiums, except an additional justification is required in Other Project Information section. Under Item 6a, mark “yes” that this “project involve activities outside the U.S.…;” under Item 6b, list the country(s) involved; and under Item 6c state “See justification under Item 12. Other Attachments,’ where you will justify the reason for work outside the U.S.. For more information, please see the appropriate application guide.

Most often, foreign research institutions do not have a DUNS #, but some do. If they not have one, then use the following for the DUNS #: 000000000 (nine zeroes). If awarded, they will be required to obtain one. With regards to an Entity Identification Number (EIN), use 44-4444444 in the Face Page. For Congressional District, use 00-000 (2 zeroes, than a dash, and three zeroes). For F&A, use 8%, unless they have a federally-negotiated F&A Rate, which is rare.

For more information on foreign involvement and collaboration, please see our page on Foreign Involvement.

Under certain circumstances, NIH allows for additional supplementary materials submitted to the Scientific Review Officer (SRO) prior to initial peer review. Additionally, this can be used when “an unexpected event such as the departure of a participant, natural disaster, etc has occurred.” This cannot be used to correct oversights and/or errors discovered post submission. For more information on what is allowable as well as the policy, please see the most recent notice on post submission application materials, NOT-OD-13-030 .

Post-submission materials are due 30 days prior to the peer review meeting. Concurrent from the Authorized Organization Representative (AOR) of the application organization is required.

A PA identifies areas of increased priority and/or emphasis on particular funding mechanisms for a specific area of science and are usually accepted on standard receipt (postmarked) dates on an on-going basis. PAs remain active for three years from date of release unless the announcement indicates a specific expiration date or the NIH Institute/Center (I/C) inactivates sooner. Find the most recent PAs and other NOFOs with NIH.

• PAR​:​ is a PA with special receipt, referral and/or review considerations, as described in the PAR announcement
• PAS:​ is a PA that includes specific set-aside funds as described in the PAS announcement.

• Career Development Awards (CDA/K series): is typically an award focused on early stage investigators to assist with further developing their careers in biomedical, behavioral, and clinical research or for researchers changing careers. Learn more at the Career Development Kiosk on the different programs as well as eligibility as well as refer to the CDA-specific SF-424 (R&R) Forms F Application Guide.

• Cooperative Agreements (U series): is a support mechanism used when there will be substantial Federal scientific or programmatic involvement. Substantial involvement means that, after the award, scientific or program staff will assist, guide, coordinate, or participate in project activities. Cooperative Agreements are typically awarded in response to an RFA and frequently they will include special terms and conditions, in addition to those that generally apply to awarded grants. The U01 is the most common of the U series and is a Research Project Cooperative Agreement that supports discrete and specific projects to be performed by investigator(s) in an area representing their specific interests and competencies. Note, that you cannot use the Modular Budget format for competing proposals. You must prepare the NIH detailed budget pages for a program project. The cooperative agreement applications follow the standard instructions of the SF424 (R&R) Forms F Application Guide.

• Individual Fellowships (F series): provide institutional research training opportunities to trainees at the graduate and postdoctoral levels. At UC San Diego, all professional degree graduate students (MD, PharmD, MD/PhD, or PharmD/PhD) and postdoctoral fellows will submit their applications through HS SPPO. Find more information on submitting an NIH fellowship through HS SPPO. Moreover, visit the NIH Fellowship Kiosk for more information on the different programs as well as eligibility and the Individual Fellowship SF424 (R&R) Application Guide.

• Institutional Training Grants (T series): provides institutional research training opportunities (including international) to trainees at the undergraduate, graduate, and postdoctoral levels, led by an established PI. Visit the NIH Research Training Kiosk for more information on the different programs as well as eligibility refer to the appropriate section of theTraining Grant specific SF424 (R&R) Forms F Application Guide.

• Program Project/Center Grants (P series): is a program project grant that provides an institution with support for a multi-disciplinary, long-term research program with an objective or theme involving groups of investigators. Awarded on behalf of a principal investigator, the grant can support multiple projects and shared resources (cores). Whereas a center grant supports shared resources for a multi-disciplinary research group of investigators focused on a common research topic. Note, that you cannot use the Modular Budget format for competing proposals. You must prepare the NIH detailed budget pages for a program project. Find for more information on the different programs as well as eligibility and refer to the appropriate section of the Multi-Project specific SF424 (R&R) Forms F Application Guide.

• Research Grants (R series): typically used to support a specified research project, or may provide limited funding for a short period of time, and they may be unsolicited or solicited applications. All ICs accept unsolicited proposals for the R01 mechanism, but for all other mechanisms, you will need to check with the NOFO to see which IC will accept proposal applications and which ones will not. Note, that modular or detailed budgets are utilized, depending on the amount requested in each budget year. Find information on research grants as well as mechanisms . The research grant applications follow the standard instructions of the SF424 (R&R) Forms F Application Guide.

• Small Business Innovation Research Grant (SBIR) & Small Business Technology Transfer Research Grants (STTR): programs are one of the largest sources of early-stage capital for innovative small companies in the United States. Per NIH, “the SBIR program funds early-stage small businesses that are seeking to commercialize innovative biomedical technologies. This competitive program helps small businesses participate in federal research and development, develop life-saving technologies, and create jobs.” While “the NIH STTR program is similar to the NIH SBIR program, but requires that the small business formally collaborate with a research institution in Phase I and Phase II.” UC San Diego is not allowed to be the prime submitting agency with either of these two types of opportunities, instead, we act as the educational component – aka consortium/subaward. Find more information on the SBIR & STTR programs.

• Streamlined Non-Competing Award Process (SNAP):​​ is a streamlined process that includes a number of provisions that modify annual progress reports, NOAs, and financial reports. Unobligated balances of under 25% are automatically carried over to the next budget year, without prior approval or permission. All NIH award notices identify whether the grant is subject to or excluded from SNAP. At UC San Diego, if an award is SNAP-eligible, then the PI has been delegated authority to submit their own progress report in the RPPR module in eRA Commons. You will need to process, on your own or with the assistance of your Fund Manager, your annual FCOI Form. Find more information on SNAP.
• Non-streamlined Non-Competing Award Process (Non-SNAP):​​ is not a streamline process or subject to the SNAP process and typically includes a detailed budget in the RPPR module in eRA Commons. At UC San Diego, if an award is NOT SNAP-eligible, then the PI does NOT have delegated authority to submit their own RPPR in eRA Commons and this will need to be submitted by your SPO Analyst. You will need to obtain a new Kuali Research Record, and Internal Budget, and process your annual FCOI Forms for all key persons on the grant.