Next Generation Researchers Initiative

NIH has launched the Next Generation Researchers Initiative to address longstanding challenges faced by researchers trying to embark upon and sustain independent research careers, and to take steps to promote the growth, stability and diversity of the biomedical research workforce.

An Early Stage Investigator (ESI) is a Program Director / Principal Investigator (PD/PI) who has completed their terminal research degree or end of post-graduate clinical training, whichever date is later, within the past 10 years and who has not previously competed successfully as PD/PI for a substantial NIH independent research award.  A list of NIH grants that a PD/PI can hold and still be considered an ESI can be found here.  ESIs are encouraged to enter the date of their terminal research degree or the end date of their post-graduate clinical training in their eRA Commons profile to ensure their correct identification.  ESI applications with meritorious scores will be prioritized for funding.

​A New Investigator is an PD/PI who has not previously received substantial, independent funding from NIH.  NIH Institutes and Centers (ICs) fund New Investigators according to the ICs' programmatic and strategic interests. 

Please note, NIH anticipates that some PD/PIs may have experienced a lapse in their research or research training or have experienced periods of less than full-time effort during their ESI or EEI status.  In order to accommodate such lapses, the NIH will consider requests to extend ESI or EEI period for reasons that can include medical concerns, disability, family care responsibilities, extended periods of clinical training, natural disasters, and active duty military service, determined on a case by case basis at the sole discretion of NIH.  You may also make this request online here.

ESIs may request an extension of their eligibility under existing ESI procedures. 

For more information on NIH's Net Generation Researchers Initiative please go here, and for more information on Early Stage Investigator Policies, please see here.

Per NOT-OD-11-057, NIH has given New Investigators (including Early Stage Investigators) the option for resubmitting their applications for consecutive review cycles. Per NIH, "this provides quicker feedback on the initial peer review and potentially minimizes delays in the progression to funding." Moreover, in order to assist New Investigators in preparing their resubmissions, NIH has chan​ged the schedule for release of summary statements for the initial R01 reviewed application and the due date for the next cycle resubmission. Please be aware that this does not apply to R01s submitted in response to an RFA or a PAR with a special due date.

Due date for New R01 (A0) application​
Study Section Meeting WindowSummary Statement Release

Due Date for Next Round Resubmission (A1)

February 5May/June/JulyJuly 10August 10
June 5Sept/Oct/NovNovember 10December 10
October 5Jan/Feb/MarchMarch 10April 10

The Early Independence Award (EIA) program is designed to help exceptional junior investigators leapfrog over traditional post doctoral training and move into independent academic positions at U.S. institutions, directly upon completion of their graduate research degrees. EIA recipients are awarded up to $250,000 in direct costs per year for up to five years for research that complements and enhances an institution's research program.

Please see NIH's EIA Program Website for additional information.

UC San Diego is only allowed to submit two (2) applications for this announcement each year. If you are interested in applying, please contact hsfunding@ucsd.edu.