Jennifer Berumen, MD
My research interests encompass multiple aspects of abdominal transplantation including outcomes analyses for liver and kidney transplantation, multi-organ transplantation, including combined heart and kidney transplantation. I also focus on studying pediatric kidney and liver transplantation, as well as have collaborations to identify inflammasomes as a therapeutic target for muscle loss in children with chronic kidney disease. I am also studying transplant related surgical issues, including peritoneal dialysis catheters and outcomes of cirrhotic patients undergoing general surgery operations. Finally, I have had a long-term interest in hepatocellular carcinoma and participate in a transplant research consortium with multiple other centers.
Sarah Blair, MD
I focus on studying breast cancer treatment. I have previously worked on using nanoparticles to localize breast tumors, and now collaborate on a project to use nanoparticles to develop a vaccine for invasive lobular carcinoma with
Dr. Kummel from the Department of Chemistry. . I also collaborate with
Dr. Eliceiri in the Division of Trauma to examine exosomes and immune modulators in breast cancer
Lastly, I focus on surgical quality in the treatment of breast cancer by leading committees through the American College of Surgeons Clinical Research Program. Working with residents, we focus on surgical quality projects using the National Cancer Database.
Ava Hosseini, MD
My research interests include ductal carcinoma in situ (DCIS), the presence of abnormal cells within the ducts of the breast. Specifically, I am interested in determining which types of DCIS progress to invasive breast cancer, needing more aggressive treatment, and which types are indolent and can be treated less aggressively. I am also interested in axillary lymph node management and I am currently studying the effect of new guidelines on clinical practice patterns by breast surgeons.
Anne Wallace, MD
Our Molecular Imaging Program is housed in the Moores Cancer Center. It includes chemical synthesis and analytical equipment, as well as high-resolution radiographic imaging instruments for the development and testing of diagnostic imaging agents. Currently, we are developing a CD44-targeted molecular imaging agent for detection of breast cancer stem cells, as well as developing a dual Tc-99m-tilmanocept imaging protocol for pre-operative lymphedema risk assessment.
Cardiovascular and Thoracic
Our program is actively involved in clinical research pertaining to cardiovascular disease, cerebral blood flow during cardiopulmonary bypass, mechanisms of transplant rejection, and pulmonary thromboendarterectomy (PET) for pulmonary hypertension.
Benjamin Abbadessa, MD
My research is primarily focused on clinical outcomes associated with the surgical management of anal dysplasia and rectal cancer. I am interested in better understanding the impact of high resolution anoscopy on anal dysplasia progression. I am also investigating nerve identification and preservation and its impact on functional outcomes following robotic rectal cancer resection.
Bard Cosman, MD
I record observations and draw conclusions from clinical practice. Areas of interest include surgical treatment of the hidradenitis suppurativa / acne inversa syndrome, which encompasses pilonidal sinus and other supposedly stand-alone conditions; expectant management of anal high-grade dysplasia in the context of immunosuppression; and anal fissure-fistula.
Sam Eisenstein, MD
My research focuses on outcomes in colon and rectal surgery with a primary interest in two areas, including new and novel techniques with minimally invasive and robotic surgery, as well as Inflammatory Bowel Disease (IBD) surgery and outcomes. Our division is constantly innovating in the minimally invasive surgical space and we are well published on our novel techniques for robotic TAMIS, robotic multi-quadrant surgery, and robotic proctectomy. We regularly assemble videos and technical papers to help other surgeons adopt these techniques.
Sonia Ramamoorthy, MD
My research focuses on colorectal and anal cancer, Crohn's disease, ulcerative colitis, and pelvic floor disorders.
Minimally Invasive Surgery
Ryan Broderick, MD
My clinical research focus on clinical and outcomes-based research for foregut, bariatric, and minimally invasive surgery.
Garth Jacobsen, MD
My clinical research is primarily focused on clinical outcomes related to abdominal wall reconstruction, bariatric surgery, and the development of minimally invasive techniques. Within those domains I have a keen interest in the utilization and development of robotic surgery platforms, and enhanced recovery protocols to improve outcomes.
Otolaryngology/Head and Neck
Matthew Brigger, MD, MPH
Leveraging our unique and busy multidisciplinary clinical practice, we have developed a broad outcomes-based research initiative that seeks to better understand and treat children with complex breathing and feeding problems. Utilizing a variety of funding sources and collaborations, we are developing a better understanding of this complex patient population and developing innovative approaches to improve surgical success. Among our endeavors, we have several exciting projects including the use of 3D printing in pediatric airway surgery, understanding the role of the microbiome in these children and development of a clinical risk stratification tool.
Adam Deconde, MD
My goal is to mitigate suffering from sinonasal pathology both through expert clinical care and through research on the refinement of that clinical care. My research niche is characterizing and capturing the outcomes associated with these interventions through prospective clinical trials and analysis of large databases. I also collaborate with basic and translational researchers in an effort to capture both patient-reported outcome measures and sinonasal pathological specimens to better understand these disease processes. While at UC San Diego we have helped refine the extent of sinus surgery, treatment of sinonasal tumors and management of postoperative sinus pain.
Jeffrey Harris, MD, PhD
Our current research interests are in multiple areas of the causes and treatments of hearing loss. I oversee programs that focus specifically on Ménière's disease, inner ear drug delivery and surgery for otosclerosis.
David Hom, MD
Our research is focused toward clinical investigations to improve soft tissue wound healing and reduce scarring resulting from trauma and surgery. We study how cytokines accelerate angiogenesis and to reduce scarring. We also are working on innovative surgical devices with the engineering department to improve surgical healing. We hope to continue collaboration with other researchers within and outside UC San Diego.
Anthony Magit, MD, MPH
I am a Clinical Professor of Surgery at UC San Diego, having joined the faculty in 1992 with a clinical practice in Pediatric Otolaryngology. Moreover, I am the Medical Director for the UC San Diego Human Research Protections Program (HRPP) and the Chief of Physician Integration for Rady Children's Hospital San Diego (RCHSD). I serve as a liaison to investigators and research teams to assist with regulatory and ethical issues related to clinical and translational research.
Ryan Orosco, MD
I am interested in optimizing surgical outcomes and translating technologies from the laboratory to the operating room. I perform large database outcomes research with NCDB, SEER, and VA databases that complements my work with UCSD CHEER (Center for Health Equity, Education & Research). Fluorescence-guided surgery is another exciting pursuit, and I am the Principal Investigator of a national trial of intraoperative fluorescence nerve imaging.
Hari Thangarajah, MD, MPH
We are actively engaged in clinical research, with a focus on traumatic injuries -- the primary cause of pediatric death and disability in the United States. I have a specific interest in traumatic brain injury (TBI) and investigate the use of biomarkers in optimizing the care of children with TBI. I also conduct research evaluating variations in resource utilization and outcomes for commonly performed pediatric surgeries, aiming to use the results of this work to enhance the quality of care provided to patients.
Plastic & Reconstructive Surgery
Amanda Gosman, MD
I have a wide breadth of research interests spanning pediatric craniofacial surgery, surgical education, quality of life, global health, and much more. I have active projects studying surgical outcomes after repair of craniosynostosis and cleft lip/palate. I have also been collaborating with San Diego State University on the development of a patient reported outcome measures for children with facial deformities.
Frederic Kolb, MD, MRes
My clinical interest is in the reconstruction of patients that have been treated for a cancer, especially using microsurgery. I lead three research programs, including: 1) bringing a surgical solution to lymphedema with a strong multidisciplinary team including occupational therapy, radiology and breast surgeons; 2) developing primary facial nerve reinnervation if injured during a patient's treatment course; and 3) validating the technique of mastectomy using a surgical robot.
Samuel Lance, MD
My research focuses on pediatrics, craniofacial trauma, and surgical education research. I have published numerous pediatric studies examining craniofacial repair, as well as minimally invasive cosmetic techniques in the pediatric population. I also have multiple ongoing projects through collaborations with ENT and the trauma surgery service investigating at enhanced recovery after surgery in facial fractures, orbital fracture repair rates and complications, and reconstruction after facial ballistic trauma.
Mark Rechnic, MD
My research efforts focus on prospective studies using antibiotic, polymer material for infected cranioplasties. I am also a study surgeon for VIACYTE, a San Diego-based regenerative medicine company that focuses on delivering novel stem cell derived replacement therapies as a functional cure for type 1 diabetes mellitus(https://viacyte.com/). Previously, I worked on acute regional pain syndrome, focusing on early treatment with continuous brachial plexus block and spinal cord stimulation.
Christopher Reid, MD
I have numerous research interests that include lymphatics, microsurgery, and healthcare systems analysis. Current projects include evaluation of the LYMPHA procedure and vascularized lymph node transfers for treatment of cancer related lymphedema. I also collaborate with faculty at Scripps Mercy Hospital to evaluate lower limb salvage amputation rates. I am also interested in investigating many healthcare systems measures including wRVU rates among different specialties performing similar procedures, and measurements of academic success among publishing researchers.
Ahmed Suliman, MD
My current research efforts focus on translational research on regenerative medicine. He is currently the study surgeon for VIACYTE, a San Diego based regenerative medicine company focusing on delivering novel stem cell derived replacement therapies as a functional cure for type 1 diabetes mellitus (https://viacyte.com/). Pluripotent stem cells are implanted in the human body and they transform into insulin producing islet cells. These technologies may revolutionize how type 1 diabetics and insulin requiring type 2 diabetics are treated. On a similar theme, I am also currently developing a model to investigate the angiogenic potential of Adipose Derived Stem Cells (ADRCs). Through neoangiogenesis, this may be a novel way to treat a host of diseases including radiation injury, chronic wounds, and organ damage.
Joel Baumgartner, MD, MAS
My research is primarily focused on clinical investigations in the diagnosis, treatment, and surveillance of patients with peritoneal metastases from a variety of primary tumors. I am interested in better understanding the disease processes (through investigating the molecular details of banked tumors and peripheral blood), predicting short- and long-term outcomes (using carefully curated clinical data from UC San Diego and beyond), and improving treatments in this disease (by investigating novel treatments in clinical trials and reviewing the efficacy of existing therapies). I have begun projects with similar objectives in cutaneous malignancies. I frequently collaborate with other clinical researchers within and outside UC San Diego.
Jason Sicklick, MD
I am the Principal Investigator a personalized-precision oncology clinical trial,
I-PREDICT (Investigation of Profile-Related Evidence Determining Individualized Cancer Therapy ). We are studying treating patients with personalized, combination therapies to improve outcomes in patients with therapy resistant cancers. This work has been published in
Jula Veerapong, MD
I lead UC San Diego Health's Enhanced Recovery After Surgery (ERAS) Program. This is a new surgery protocol that streamlines patient processes before, during and after surgeries. The program aims to shorten the length of stay for patients and facilitate early mobility and recovery while improving outcomes and patients' overall experiences. While developing and implementing this program, I am particularly interested in studying the efficacy and outcomes of this approach. I am also focused on surgical outcomes in patients with peritoneal based malignancies undergoing CytoReductive Surgery (CRS) with or without Hyperthermic IntraPEritoneal Chemotherapy (HIPEC). Partnering with the Gynecology Oncology Division, I am investigating the role of HIPEC in increasing overall survival in ovarian cancer.
Transplantation and Hepatobiliary
Gabriel Schnickel, MD, MPH
I am the Surgical Director of Liver Transplantation and leading UC San Diego Health in two national clinical trials to evaluate the effectiveness of normothermic machine perfusion of donor livers intended for transplantation to preserve them and assess outcomes. Additionally, my research interests focus on liver transplant outcomes using multicenter data and larger prospective databases.
Jay Doucet, MD, MSc
My clinical research is focused on trauma and critical care, in particular the use of point-of-care ultrasound to detect occult shock, and ventilatory strategies and transfusion strategies in trauma patients to reduce complications. I also conduct health services research looking at social determinants in trauma and emergency surgery patients and also by using geospatial information systems analysis (GIS) to identify locations with inequities in access to surgical care and surgical outcomes.
Sara Higginson, MD
My clinical research interests are in burn, wound and trauma outcomes. We are examining potential therapies for chronic wounds and I also research determinants in non-operative management of solid organ injuries. Our educational research interests are in simulation methods for enhanced team performance and procedural skills.
Jeanne Lee, MD
My research pursuits lie in the area of burn resuscitation. Burn centers are still working on the ideal method of resuscitating burn patients and debate is still ongoing regarding the use of colloids, both albumin and FFP, and how to gauge optimal crystalloid usage. Secondly, I continuously engage in industry sponsored research mostly in the area of burn healing. We currently have two protocols that will be implemented involving the use of spray cell technology in the pediatric population and the impact on their healing and potentially their length of stay.
Mahmoud Malas, MD (Chief), John Lane, MD, MS, Andrew Barleben, MD Omar Al-Nouri, MD & Luis Cajas, MD
With our robust portfolio of clinical trials, our division remains at the cutting edge of new advances in vascular and endovascular surgery. We are currently participating in 12 clinical trials in the areas of dialysis access, aortic aneurysm repair, treatment of peripheral arterial disease and management of carotid artery atherosclerotic disease. We are also interested in flow modeling, peripheral interventions, arterial sac embolization, the latest endografts for abdominal aneurysm repair and racial disparities in peripheral interventions.
Allison Berndtson, MD
My research is primarily focused in two areas – trauma\EGS clinical outcomes research and global surgery. Globally, my focus is on trauma education and systems development. We incorporate research into these pursuits to inform quality improvement projects and evaluate the outcomes of our interventions. I work with partners in Ghana, Nigeria, Mozambique and Tijuana, Mexico.
Stephen Bickler, MD
Our research interests include surgical epidemiology, global surgery, and all aspects of pediatric surgery. Over the past Five years, our research has included epidemiological modeling studies using large datasets to estimate the burden of surgical diseases for the Lancet Commission on Global Surgery and the 3rd Edition Disease Control Priorities (World Bank). We are also interested in the biological changes that occur with the transition from a rural to an urban environment in sub-Saharan Africa and their relation to the origins of noncommunicable diseases. Recent studies have focused on how urbanization impacts the expression of nuclear genes encoding mitochondrial proteins.
Amanda Gosman, MD
Our Division of Plastic & Reconstructive Surgery is a leader in global health through our efforts to improve access to plastic surgery training in developing countries.