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Lymphatic Exosomes in Health and Disease Network

About the Lymphatic Exosomes in Health and Disease Network

The Lymphatic Exosomes in Health and Disease (LEHD) Network is a multidisciplinary partnership composed of with expertise in exosome biogenesis, immunology cross-talk, vesicle flow cytometry, animal models and clinical samples. We are particularly focused on the exosomes released into mesenteric lymphatics and their biological function in trauma/hemorrhagic shock and in experimental models of colitis/inflammatory bowel disease.


​Investigators

Brian Eliceiri, PhD – UC San Diego
Andrew Baird, PhD – UC San Diego
Todd Costantini, MD – UC San Diego
John Nolan, PhD – CellArcus Technologies
Sarah Blair, MD – UC San Diego
Sandip Patel, MD – UC San Diego
Phillip Stahl, PhD – Washington University in St. Louis


Journal Club

Exosomes: Looking back three decades and into the future

Quantifying exosome secretion from single cells reveals a modulatory role for GPCR signaling

Exosome RNA Unshielding Couples Stromal Activation to Pattern Recognition Receptor Signaling in Cancer

Adipose Tissue Macrophage-Derived Exosomal miRNAs Can Modulate In Vivo and In Vitro Insulin Sensitivity