Bipolar Aging and Imaging Study:
We conducted a research study about brain aging with individuals who have a diagnosis of Bipolar I Disorder. We used functional and structural neuroimaging techniques along with other measures to assess how aging may differentially affect individuals with bipolar disorder as compared to those without the disorder. Data from this study will contribute to Global Neuroimaging analysis through the ENIGMA Bipolar Disorder Working Group
Psychobiology of Cognition and Positive Traits in Aging:
We were interested in understanding how individual levels of compassion, empathy, and other positive psychological traits (for example, resilience and optimisum) related to differences in brain function and well-being across the lifespan. To understand these differences, we used multiple methods, including those from cognitive neuroscience, neuropsychology, biology, psychiatry, social psychology, and medical anthrolopology.
Gender and the Brain:
The primary focus of this study was to identify biological substrates of gender identity in the brain. Observations of individuals with Alternating Gender Identity (AGI) allows for a unique opportunity to better examine the biological foundations of mental sex. Functional magnetic resonance imaging (MRI) measures and endocrinological measures were used to assess changes in resting state connectivity and hormonal fluctuations. We aimed to understand how functional connectivity in the optimism, default mode of network, hypothesized to be critical in self-referential cognition, was affected by gender state.