Atsushi Miyanohara, Ph.D., is an experienced molecular biologist who has supervised the Vector Core Laboratory of the UCSD Program in Human Gene Therapy since its inception in 1995. He has longstanding extensive experience dealing with the design, preparation and properties of retrovirus, lentivirus, HSV1, adenovirus and AAV vectors. Dr. Miyanohara is one of the principals in the development of the VSV-G pseudotyping and VSV-G virosome technologies.
Dr. Miyanohara’s major research focus has been development of safe and efficient gene transfer vectors not only for gene therapy applications, but also for a variety of basic research including stem cells, cell reprogramming and transgenesis.
As the Director of the Vector Core Laboratory, Dr. Miyanohara has extensive mutual research collaborations and has made important conceptual and technical advances in basic and clinical gene therapy, particularly in neurological and cardiovascular diseases.
Dr. Miyanohara received his Ph.D. in Medical Sciences from Osaka University in Japan. Before he came to UCSD, his research had included hepatitis B virus, recombinant production of blood coagulation factor VIII, and hybrid-toxins for AIDS and cancer therapy. He is an inventor of many patents including the hepatitis B vaccines derived from human plasma and recombinant DNA technology, hybrid-toxins, and retrovirus packaging cell lines.