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Grossfeld Lab

We are a world-class group of physician-scientists that are dedicated to studying human diseases using state-of-the art technologies at UCSD, all aimed at helping patients (i.e., patient-driven). Using a combination of human and animal genetic model systems, our aim is to unravel the genetic mechanisms of congenital heart disease and cognitive  disorders in order to develop improved therapies and ultimately, preventive strategies.


The only basic/translational science lab in the world studying Jacobsen syndrome, combining both a human genetics and animal model approach. By studying JS, what we learn from this rare disorder will have very important implications to a much larger group of patients, e.g., those with congenital heart disease, cognitive impairment and autism. All the research starts with human patients, with the ultimate goal of developing new strategies to improve diagnosis, treat, and potentially prevent these diseases.


GIVE HOPE For every bottle of Vanilla Chill purchased, 20 cents will be donated to Little Hearts Big Hopes, an organization devoted to research that provides important insights into some of the most prevalent forms of congenital heart defects in humans.


University of California San Diego Foundation (EIN 95-6006144), Pediatric Cardiology Jacobsen Syndrome Research Fund (F-4187).  Click here to go directly to the UCSD online giving site