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Welcome to The Croker Lab

The Life and Death of Neutrophils

The production, function, and death of neutrophils is critical for host defense against pathogens. The laboratory studies a novel phenomena called shuttling, which involves the transfer of intracellular pathogens from neutrophils to macrophages. We also investigate how cell death signaling controls cytokine secretion, NET formation, neutrophil lifespan, and chronic inflammatory diseases.