Joseph Rainaldi, BS, MS, Master's Student Researcher
Joseph received his BS and MS in Biomedical Engineering with a Specialization in Regenerative Medicine and minor in Biotechnology from Cal Poly, San Luis Obispo in 2020. While at Cal Poly, he worked to increase transgene packaging efficiency into yeast HIV virus like particles until he joined the Cherqui Lab in September 2019 as a CIRM Masters Intern. Here, Joseph is engaged in translating a CRISPR/Cas9 mediated hematopoietic stem cell (HSC) therapy for the treatment of Friedreich’s ataxia from bench to bedside and developing a targeted cell therapy for the ocular pathology of cystinosis. Additionally, he is studying ways to overcome current shortcomings experienced when using the CRISPR system to edit HSCs. He is driven by the potential genetic therapeutics have to treat disease efficiently and effectively.