University of California San Diego School of Medicine researchers have been awarded nearly $9 million to fund two multi-institutional research projects that use human pluripotent stem cells, CRISPR and human organoids to dissect beta cell defects and create a human cell model of type 1 diabetes aimed at identifying the elusive cellular actions leading to disease onset. Read More
Pictured are blood vessels in green and islets (cell nuclei) in magenta.
How immune system influences insulin-producing beta cells remains poorly understood. A new study led by Wenxian Fu, Assistant Professor at the Pediatric Diabetes Research Center and Jerrold Olefsky, Professor in the Department of Medicine show that macrophages, a special subset of immune cells, dominate obesity-associated inflammation in pancreatic islets. Read More
Multi-million dollar grant will fund human atlas aimed at identifying changes leading to type 1 diabetes. Read More