How immune system influences insulin-producing beta cells remains poorly understood. A new study led by Wenxian Fu, Assistant Professor at the Pediatric Diabetes Research Center and Jerrold Olefsky, Professor in the Department of Medicine show that macrophages, a special subset of immune cells, dominate obesity-associated inflammation in pancreatic islets. They also report that macrophages affect both beta cell function and replication through different mechanisms. Read More
Multi-million dollar grant will fund human atlas aimed at identifying changes leading to type 1 diabetes. Read More
Researchers at the UC San Diego's Pediatric Diabetes Research Center identified immune cells that can restore immune tolerance in type 1 diabetes. Targeting these immune cells could be a therapeutic strategy for preventing this disease. Read More
Researchers at UC San Diego School of Medicine identified pathways that regulate pancreatic beta cell (pictured in green) growth. These cells help maintain normal blood glucose levels by producing the hormone insulin. Read More
The NIH awards PDRC researchers, Drs. Maike Sander, and Kyle Gaulton, and UCSD colleagues $3.3 million to link T1D to its genetic origins. Read More