Pediatric Diabetes Research Center (PDRC)
Assistant Professor, UCSD Department of Pediatrics
Dr. Jane Kim is an assistant professor at UCSD’s Department of Pediatrics and a physician-scientist in the UCSD Division of Pediatric Endocrinology. Her medical education began at the University of Toronto, followed by a pediatric residency at the Hospital for Sick Children.
Committed to pursuing endocrine research that integrates molecular biology, genetics and medicine, Dr. Kim moved to the National Institutes of Health (NIH) Headquarters. There, Dr. Kim complete her pediatric endocrinology fellowship. To gain additional expertise in diabetes research, Dr. Kim did her postdoctoral research training at the Naomi Berrie Diabetes Center at Columbia University, New York. In 2004, Dr. Kim joined the UCSD faculty at the School of Medicine.
Dr. Kim's clinical translational research aims to identify early biomarkers for diabetic complications, in particular kidney disease. For these studies she profiles urine samples from large numbers of patients with T1D. Patients at risk could then take dietary precautions or medications to prevent loss of kidney function.
Osborn O, Oh D, McNelis J, Sanchez-Alavez M, Talukdar S, Lu M, Li P, Thiede L, Morinaga H,
Kim JJ, Heinrichsdorff J, Nalbandian S, Ofrecio JM, Scadeng M, Schenk S, Hadcock J, Bartfai T, Olefsky JM. Deletion of G protein coupled receptor 21 (GPR21) improves insulin sensitivity in diet-induced obese mice. J Clin Invest. 2012 Jul 2;122(7):2444-53. PMID: 22653059
Xu J, Morinaga H, Oh D, Li P, Chen A, Talukdar S, Mamane Y, Mancini JA, Nawrocki AR, Lazarowski E, Olefsky JM,
Kim JJ. GPR105 ablation improves inflammation and insulin sensitivity in mice with diet-induced obesity. J Immunol, 2012 Aug 15;189(4):1992-9. PMID: 22778393
Lee YS, Morinaga H,
Kim JJ, Lagakos W, Taylor S, Keshwani M, Perkins G, Dong H, Kayali AG, Sweet IR, Olefsky JM. The Fractalkine and CX3CR1 system regulates beta cell function and insulin secretion. Cell 2013 Apr 11;153(2):413-25. PMID: 23582329
Chen, K, Jih A, Kavaler ST, Oh D, Lagakos WS, Kim JJ. Dual actions of a novel bifunctional compound to lower glucose in mice with diet-induced insulin resistance. Am J Physiol Endocrinol Metab. 2015 Aug 1;309(3):E293-301.
Kesby JP, Kim JJ, Scadeng M, Woods G, Kado D, Jeste DV, Achim CL, Semenova S. Spatial cognition in adult and aged mice exposed to high-fat diet PLOS ONE. 2015 Oct 8;10(10):e0140034.