Lars Bode, PhD
Maloney P, Hedrick M, Peddibhotla S, Hershberger P, Milewski M, Gosalia P, Li L, Preuss J, Sugarman E, Hood B, Suyama E, Nguyen K, Vasile S, Sergienko E, Salanawil S, Stonich D, Su Y, Dahl R, Mangravita-Novo A, Vicchiarelli M, McAnally D, Smith LH, Roth G, Diwan J, Chung TDY, Pinkerton AB, Bode L, Becker K. A Selective Inhibitor of Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase (PfG6PDH), 2011 Dec 16 [updated 2013 Mar 7]. Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
Preuss J, Richardson AD, Pinkerton A, Hedrick M, Sergienko E, Rahlfs S, Becker K, Bode L. Identification and characterization of novel human glucose-6-phosphate dehydrogenase inhibitors. J Biomol Screen, 18(3):286-97, 2013.
Bode L, Kuhn L, Kim HY, Hsiao L, Nissan C, Sinkala M, Kankasa C, Mwiya M, Thea DM, Aldrovandi GM. Human milk oligosaccharide concentration and risk ofpostnatal transmission of HIV through breastfeeding. Am J Clin Nutr, 6(4):831-9, 2012.
Preuss J, Maloney P, Peddibhotla S, Hedrick MP, Hershberger P, Gosalia P, Milewski M, Li YL, Sugarman E, Hood B, Suyama E, Nguyen K, Vasile S, Sergienko E, Mangravita-Novo A, Vicchiarelli M, McAnally D, Smith LH, Roth GP, Diwan J, Chung TD, Jortzik E, Rahlfs S, Becker K, Pinkerton AB, Bode L. Discovery of a Plasmodium falciparum glucose-6-phosphate dehydrogenase 6-phosphogluconolactonase inhibitor (R,Z)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-(2-fluorobenzylidene)-3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazine-6-carboxamide (ML276) that reduces parasite growth in vitro. J Med Chem, 55(16):7262-72, 2012.
Bode L. [Researchers discover a unique human milk oligosaccharide]. Kinderkrankenschwester, 31(5):214, 2012.
Bode L, Jantscher-Krenn E. Structure-function relationships of human milk oligosaccharides. Adv Nutr, 3(3):383S-91S, 2012.
Bode L. Human milk oligosaccharides: every baby needs a sugar mama. Glycobiology, 22(9):1147-62, 2012.
Preuss J, Hedrick M, Sergienko E, Pinkerton A, Mangravita-Novo A, Smith L, Marx C, Fischer E, Jortzik E, Rahlfs S, Becker K, Bode L. High-throughput screening for small-molecule inhibitors of plasmodium falciparumglucose-6-phosphate dehydrogenase 6-phosphogluconolactonase. J Biomol Screen, 17(6):738-51, 2012.
Jantscher-Krenn E, Lauwaet T, Bliss LA, Reed SL, Gillin FD, Bode L. Humanmilk oligosaccharides reduce Entamoeba histolytica attachment and cytotoxicity in vitro. Br J Nutr, 108(10):1839-46, 2012.
Jantscher-Krenn E, Zherebtsov M, Nissan C, Goth K, Guner YS, Naidu N, Choudhury B, Grishin AV, Ford HR, Bode L. The human milk oligosaccharide disialyllacto-N-tetraose prevents necrotising enterocolitis in neonatal rats. Gut, 61(10):1417-25, 2012.
Farhad Imam, MD, PhD
Cloete E, Battin MR, Imam FB, Teele RL. Ossification of sacral vertebralbodies in neonates born 24 to 38 weeks’ gestational age and its relevance to spinal ultrasonography. Am J Perinatol, 30(6):519-22, 2013.
Jae Kim, MD, PhD
Sauberan J, Rossi S, Kim JH. Stability of dilute oral morphine solution for neonatal abstinence syndrome. J Addict Med, 7(2):113-5, 2013.
Stellwagen LM, Vaucher YE, Chan CS, Montminy TD, Kim JH. Pooling expressed breastmilk to provide a consistent feeding composition for premature infants. Breastfeed Med, 8:205-9, 2013.
Ramos GA, Hanley AA, Aguayo J, Warshak CR, Kim JH, Moore TR. Neonatal chemical hypoglycemia in newborns from pregnancies complicated by type 2 and gestational diabetes mellitus - the importance of neonatal ponderal index. J Matern Fetal Neonatal Med, 25(3):267-71, 2012.
Sanjay Nigam, MD
Martovetsky G, Tee JB, Nigam SK. Hepatocyte Nuclear Factors 4a and 1a (Hnf4a and Hnf1a) Regulate Kidney Developmental Expression of Drug-Metabolizing Enzymes and Drug Transporters. Mol Pharmacol, 2013 Sep 13.
Sharma K, Karl B, Mathew AV, Gangoiti JA, Wassel CL, Saito R, Pu M, Sharma S, You YH, Wang L, Diamond-Stanic M, Lindenmeyer MT, Forsblom C, Wu W, Ix JH, IdekerT, Kopp JB, Nigam SK, Cohen CD, Groop PH, Barshop BA, Natarajan L, Nyhan WL, Naviaux RK. Metabolomics Reveals Signature of Mitochondrial Dysfunction in Diabetic Kidney Disease. J Am Soc Nephrol, 2013 Aug 15.
Wu W, Jamshidi N, Eraly SA, Liu HC, Bush KT, Palsson BO, Nigam SK. Multispecific drug transporter slc22a8 (oat3) regulates multiple metabolic and signaling pathways. Drug Metab Dispos, 41(10):1825-34, 2013.
Nagle MA, Wu W, Eraly SA, Nigam SK. Organic anion transport pathways in antiviral handling in choroid plexus in Oat1 (Slc22a6) and Oat3 (Slc22a8) deficient tissue. Neurosci Lett, 2013 Feb 8;534:133-8.
Nigam SK. The storytelling brain. Commentary on “On social attribution: implications of recent cognitive neuroscience research for race, law, and politics”. Sci Eng Ethics, 18(3):567-71, 2012.
Gallegos TF, Martovetsky G, Kouznetsova V, Bush KT, Nigam SK. Organic anion
Lawrence (Lance) Prince, MD, PhD
Morrisey EE, Cardoso WV, Lane RH, Rabinovitch M, Abman SH, Ai X, Albertine KH, Bland RD, Chapman HA, Checkley W, Epstein JA, Kintner CR, Kumar M, Minoo P, Mariani TJ, McDonald DM, Mukouyama YS, Prince LS, Reese J, Rossant J, Shi W, Sun X, Werb Z, Whitsett JA, Gail D, Blaisdell CJ, Lin QS. Molecular determinants of lung development. Ann Am Thorac Soc, 10(2):S12-6, 2013.
Carver BJ, Plosa EJ, Stinnett AM, Blackwell TS, Prince LS. Interactions between NF-κB and SP3 connect inflammatory signaling with reduced FGF-10 expression. J Biol Chem, 288(21):15318-25, 2013.
Sen P, Yang Y, Navarro C, Silva I, Szafranski P, Kolodziejska KE, Dharmadhikari AV, Mostafa H, Kozakewich H, Kearney D, Cahill JB, Whitt M, Bilic M, Margraf L, Charles A, Goldblatt J, Gibson K, Lantz PE, Garvin AJ, Petty J, Kiblawi Z, Zuppan C, McConkie-Rosell A, McDonald MT, Peterson-Carmichael SL, Gaede JT, Shivanna B, Schady D, Friedlich PS, Hays SR, Palafoll IV, Siebers-Renelt U, Bohring A, Finn LS, Siebert JR, Galambos C, Nguyen L, Riley M, Chassaing N, Vigouroux A, Rocha G, Fernandes S, Brumbaugh J, Roberts K, Ho-Ming L, Lo IF, Lam S, Gerychova R, Jezova M, Valaskova I, Fellmann F, Afshar K, Giannoni E, Muhlethaler V, Liang J, Beckmann JS, Lioy J, Deshmukh H, Srinivasan L, Swarr DT, Sloman M, Shaw-Smith C, van Loon RL, Hagman C, Sznajer Y, Barrea C, Galant C, Detaille T, Wambach JA, Cole FS, Hamvas A, Prince LS, Diderich KE, Brooks AS, Verdijk RM, Ravindranathan H, Sugo E, Mowat D, Baker ML, Langston C, Welty S, Stankiewicz P. Novel FOXF1 mutations in sporadic and familial cases of alveolar capillary dysplasia with misaligned pulmonary veins imply a role for its DNA binding domain. Hum Mutat, 34(6):801-11, 2013.
Goudy S, Angel P, Jacobs B, Hill C, Mainini V, Smith AL, Kousa YA, Caprioli R, Prince LS, Baldwin S, Schutte BC. Cell-autonomous and non-cell-autonomous roles for IRF6 during development of the tongue. PLoS One. 2013;8(2):e56270.
Plosa EJ, Gooding KA, Zent R, Prince LS. Nonmuscle myosin II regulation of lung epithelial morphology. Dev Dyn, 241(11):1770-81, 2012.
Fike CD, Sidoryk-Wegrzynowicz M, Aschner M, Summar M, Prince LS, Cunningham G, Kaplowitz M, Zhang Y, Aschner JL. Prolonged hypoxia augments L-citrulline transport by system A in the newborn piglet pulmonary circulation. Cardiovasc Res, 95(3):375-84, 2012.
Zhang C, Sherman MP, Prince LS, Bader D, Weitkamp JH, Slaughter JC, McElroy SJ. Paneth cell ablation in the presence of Klebsiella pneumoniae induces necrotizing enterocolitis (NEC)-like injury in the small intestine of immature mice. Dis Model Mech, 5(4):522-32, 2012.
Humphreys R, Zheng W, Prince LS, Qu X, Brown C, Loomes K, Huppert SS, Baldwin S, Goudy S. Cranial neural crest ablation of Jagged1 recapitulates the craniofacial phenotype of Alagille syndrome patients. Hum Mol Genet, 21(6):1374-83, 2012.
Yamamoto Y, Baldwin HS, Prince LS. Endothelial differentiation by multipotent fetal mouse lung mesenchymal cells. Stem Cells Dev, 21(9):1455-65, 2012. Blackwell TS, Hipps AN, Yamamoto Y, Han W, Barham WJ, Ostrowski MC, Yull FE, Prince LS. NF-κB signaling in fetal lung macrophages disrupts airway morphogenesis. J Immunol, 187(5):2740-7, 2011.
McElroy SJ, Prince LS, Weitkamp JH, Reese J, Slaughter JC, Polk DB. Tumornecrosis factor receptor 1-dependent depletion of mucus in immature small intestine: a potential role in neonatal necrotizing enterocolitis. Am J Physiol Gastrointest Liver Physiol, 301(4):G656-66, 2011.
Lisa Stellwagen, MD
Sauberan JB, Bradley JS, Blumer J, Stellwagen LM. Transmission of meropenem in breast milk. Pediatr Infect Dis J, 31(8):832-4, 2012.
Denise Suttner, MD Wessel DL, Berger F, Li JS, Dähnert I, Rakhit A, Fontecave S, Newburger JW; CLARINET Investigators. Clopidogrel in infants with systemic-to-pulmonary-artery shunts. N Engl J Med, 368(25):2377-84, 2013.