Nachman S, Alvero C, Acosta EP, Teppler H, Homony B, Graham B, Fenton T, Xu X,
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Brummel SS, Singh KK, Maihofer AX, Farhad M, Qin M, Fenton T, Nievergelt CM,
Spector SA. Associations of Genetically Determined Continental Ancestry with CD4+
Count and Plasma HIV-1 RNA beyond Self-Reported Race and Ethnicity. J Acquir
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Campbell GR, Rawat P, Bruckman RS, Spector SA. Human Immunodeficiency Virus
Type 1 Nef Inhibits Autophagy through Transcription Factor EB Sequestration. PLoS
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Marsit CJ, Brummel SS, Kacanek D, Seage GR 3rd, Spector SA, Armstrong DA,
Lester BM, Rich K; Pediatric HIV/AIDS Cohort Studies Network. Infant peripheral
blood repetitive element hypomethylation associated with antiretroviral therapy
in utero. Epigenetics. 2015;10(8):708-16. doi: 10.1080/15592294.2015.1060389.
PubMed PMID: 26067216; PubMed Central PMCID: PMC4622750.
Curtis DJ, Muresan P, Nachman S, Fenton T, Richardson KM, Dominguez T, Flynn
PM, Spector SA, Cunningham CK, Bloom A, Weinberg A. Characterization of
functional antibody and memory B-cell responses to pH1N1 monovalent vaccine in
HIV-infected children and youth. PLoS One. 2015 Mar 18;10(3):e0118567. doi:
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Chaparro JD, Leake JAD. Parasitic disease in the pediatric intensive care unit – A review of severe manifestations of pediatric parasitic disease. Journal of Pediatric Intensive Care. 2014; 3: 291-304.
Chaparro J, Murphy E, Davis CJ, Viani RM, Pong A. Case Report: Chest pain and shortness of breath in a previously healthy teenager. Journal of the Pediatric Infectious Diseases Society 2014; doi: 10.1093/jpids/piu036.
Andrade RM, Chaparro JD, Capparelli E, Reed SL (2014) Auranofin Is Highly Efficacious against Toxoplasma gondii In Vitro and in an In Vivo Experimental Model of Acute Toxoplasmosis. PLoS Negl Trop Dis 8(7): e2973. doi:10.1371/journal.pntd.0002973
Moodley A, Spector SA. Single high-dose vitamin D at birth corrects vitamin D
deficiency in infants in Mexico. Int J Food Sci Nutr. 2015 May;66(3):336-41. doi:
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Campbell GR, Bruckman RS, Chu YL, Spector SA. Autophagy induction by histone
deacetylase inhibitors inhibits HIV type 1. J Biol Chem. 2015 Feb
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Garg A, Rawat P, Spector SA. Interleukin 23 produced by myeloid dendritic
cells contributes to T-cell dysfunction in HIV type 1 infection by inducing SOCS1
expression. J Infect Dis. 2015 Mar 1;211(5):755-68. doi: 10.1093/infdis/jiu523.
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Mandala WL, Ananworanich J, Apornpong T, Kerr SJ, MacLennan JM, Hanson C,
Jaimulwong T, Gondwe EN, Rosenblatt HM, Bunupuradah T, Molyneux ME, Spector SA, Pancharoen C, Gelman RS, MacLennan CA, Shearer WT. Control lymphocyte subsets: can one country's values serve for another's? J Allergy Clin Immunol. 2014
Sep;134(3):759-761.e8. doi: 10.1016/j.jaci.2014.06.030. PubMed PMID: 25171870;
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Clarke DF, Acosta EP, Rizk ML, Bryson YJ, Spector SA, Mofenson LM, Handelsman
E, Teppler H, Welebob C, Persaud D, Cababasay MP, Wang J, Mirochnick M;
International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) P1097
Study Team. Raltegravir pharmacokinetics in neonates following maternal dosing. J
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Viani RM, Araneta MR, Spector SA. In-Country Migration and Risk Factors for
HIV Acquisition among Pregnant Women in Tijuana, Mexico. J Int Assoc Provid AIDS
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Qin M, Brummel S, Singh KK, Fenton T, Spector SA. Associations of host
genetic variants on CD4⁺ lymphocyte count and plasma HIV-1 RNA in antiretroviral
naïve children. Pediatr Infect Dis J. 2014 Sep;33(9):946-52. doi:10.1097/INF. 0000000000000330. PubMed PMID: 24797997; PubMed Central PMCID: PMC4216611.
Berry SA, Gebo KA, Rutstein RM, Althoff KN, Korthuis PT, Gaur AH, Spector SA,
Warford R, Yehia BR, Agwu AL; HIV Research Network. Trends in hospitalizations
among children and young adults with perinatally acquired HIV. Pediatr Infect Dis
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Pass RF, Nachman S, Flynn PM, Muresan P, Fenton T, Cunningham CK, Borkowsky
W, McAuley JB, Spector SA, Petzold E, Levy W, Siberry GK, Handelsman E, Utech LJ,
Weinberg A; IMPAACT 1089 Team. Immunogenicity of Licensed Influenza A (H1N1) 2009. Monovalent Vaccines in HIV-Infected Children and Youth. J Pediatric Infect Dis
Soc. 2013 Dec;2(4):352-60. doi: 10.1093/jpids/pit040. Epub 2013 Jul 17. PubMed
PMID: 24363932; PubMed Central PMCID: PMC3869470.
Essajee SM, Arpadi SM, Dziuban EJ, Gonzalez-Montero R, Heidari S, Jamieson
DG, Kellerman SE, Koumans E, Ojoo A, Rivadeneira E, Spector SA, Walkowiak H;
Child Survival Working Group of the Interagency Task Team on the Prevention and
Treatment of HIV infection in Pregnant Women, Mothers and Children. Pediatric
treatment 2.0: ensuring a holistic response to caring for HIV-exposed and
infected children. AIDS. 2013 Nov;27 Suppl 2:S215-24. doi:10.1097/ QAD.0000000000000091. PubMed PMID: 24361631; PubMed Central PMCID:
PMC4682195.
Nachman S, Zheng N, Acosta EP, Teppler H, Homony B, Graham B, Fenton T, Xu X,
Wenning L, Spector SA, Frenkel LM, Alvero C, Worrell C, Handelsman E, Wiznia A;
International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) P1066
Study Team. Pharmacokinetics, safety, and 48-week efficacy of oral raltegravir in
HIV-1-infected children aged 2 through 18 years. Clin Infect Dis. 2014
Feb;58(3):413-22. doi: 10.1093/cid/cit696. Epub 2013 Oct 21. PubMed PMID:
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Garg A, Spector SA. HIV type 1 gp120-induced expansion of myeloid derived
suppressor cells is dependent on interleukin 6 and suppresses immunity. J Infect
Dis. 2014 Feb 1;209(3):441-51. doi: 10.1093/infdis/jit469. Epub 2013 Sep 1.
PubMed PMID: 23999600; PubMed Central PMCID: PMC3883171.
Dehority W, Deville JG, Lujan-Zilbermann J, Spector SA, Viani RM. Effect of
HIV genotypic drug resistance testing on the management and clinical course of
HIV-infected children and adolescents. Int J STD AIDS. 2013 Jul;24(7):549-53.
doi: 10.1177/0956462412473958. Epub 2013 Jul 4. PubMed PMID: 23970770.
Campbell GR, Spector SA. Inhibition of human immunodeficiency virus type-1
through autophagy. Curr Opin Microbiol. 2013 Jun;16(3):349-54. doi:
10.1016/j.mib.2013.05.006. Epub 2013 Jun 5. Review. PubMed PMID: 23747172; PubMed Central PMCID: PMC3742638.
Moodley A, Qin M, Singh KK, Spector SA. Vitamin D-related host genetic
variants alter HIV disease progression in children. Pediatr Infect Dis J. 2013
Nov;32(11):1230-6. doi: 10.1097/INF.0b013e31829e4d06. PubMed PMID: 23736144; PubMed Central PMCID: PMC3811908.
Yehia BR, Agwu AL, Schranz A, Korthuis PT, Gaur AH, Rutstein R, Sharp V,
Spector SA, Berry SA, Gebo KA. Conformity of pediatric/adolescent HIV clinics to
the patient-centered medical home care model. AIDS Patient Care STDS. 2013
May;27(5):272-9. doi: 10.1089/apc.2013.0007. PubMed PMID: 23651104; PubMed
Central PMCID: PMC3651683.
Spector SA, Qin M, Lujan-Zilbermann J, Singh KK, Warshaw MG, Williams PL,
Jean-Philippe P, Fenton T, Siberry GK; IMPAACT P1065 Protocol Team. Genetic
variants in toll-like receptor 2 (TLR2), TLR4, TLR9, and FCγ receptor II are
associated with antibody response to quadrivalent meningococcal conjugate vaccine
in HIV-infected youth. Clin Vaccine Immunol. 2013 Jun;20(6):900-6. doi:
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Campbell GR, Pallack ZT, Spector SA. Vitamin D attenuates nucleoside reverse
transcriptase inhibitor induced human skeletal muscle mitochondria DNA depletion.
AIDS. 2013 Jun 1;27(9):1397-401. doi: 10.1097/QAD.0b013e32836010dd. PubMed PMID: 23435299; PubMed Central PMCID: PMC3762245.
Weinberg A, Muresan P, Fenton T, Richardson K, Dominguez T, Bloom A, Petzold
E, Anthony P, Cunningham CK, Spector SA, Nachman S, Siberry GK, Handelsman E,
Flynn PM; IMPAACT P1088 study team. High proportions of regulatory B and T cells
are associated with decreased cellular responses to pH1N1 influenza vaccine in
HIV-infected children and youth (IMPAACT P1088). Hum Vaccin Immunother. 2013
May;9(5):957-68. doi: 10.4161/hv.23774. Epub 2013 Jan 31. PubMed PMID: 23370281; PubMed Central PMCID: PMC3899162.
Shoji-Kawata S, Sumpter R, Leveno M, Campbell GR, Zou Z, Kinch L, Wilkins AD,
Sun Q, Pallauf K, MacDuff D, Huerta C, Virgin HW, Helms JB, Eerland R, Tooze SA,
Xavier R, Lenschow DJ, Yamamoto A, King D, Lichtarge O, Grishin NV, Spector SA,
Kaloyanova DV, Levine B. Identification of a candidate therapeutic
autophagy-inducing peptide. Nature. 2013 Feb 14;494(7436):201-6. doi:
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Singh KK, Wang Y, Gray KP, Farhad M, Brummel S, Fenton T, Trout R, Spector
SA. Genetic variants in the host restriction factor APOBEC3G are associated with
HIV-1-related disease progression and central nervous system impairment in
children. J Acquir Immune Defic Syndr. 2013 Feb 1;62(2):197-203. doi:
10.1097/QAI.0b013e31827ab612. PubMed PMID: 23138837; PubMed Central PMCID:PMC3658306.
Viani RM, Araneta MR, Spector SA. Parallel rapid HIV testing in pregnant
women at Tijuana General Hospital, Baja California, Mexico. AIDS Res Hum
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19. PubMed PMID: 23050550.
Sarnquist C, Sawyer M, Calvin K et al. Communicating about vaccines and vaccine safety: what are medical residents learning and what do they want to learn? J Public Health Manag Pract. 2013: 19:40-6
McAuliffe K, Peddecord KM, Wang W, Ralston K, Deguire M, Waters-Montijo K, Sawyer MH. Influenza Vaccination and Its Association With Clinic Use of Evidence-Based Practices and Individual Patient Characteristics, San Diego County, 2009.. J Public Health Manag Pract. 2013 Mar;19(2):178-186.
Nagel AC, Tsou MH, Spitzberg BH, An L, Gawron JM, Gupta DK, Yang JA, Han S, Peddecord KM, Lindsay S, Sawyer MH. The complex relationship of real space events and messages in cyberspace: case study of influenza and pertussis using tweets. J Med Internet Res. 2013 Oct 24;15(10):e237. doi: 10.2196/jmir.2705
Rosenblum E, McBane S, Wang W, Sawyer M. Protecting newborns by immunizing family members in a hospital-based vaccine clinic: a successful program during the 2010 California pertussis epidemic. Public Health Reports 129:245-251.
Djibo DA, Peddecord KM, Wang W, Ralston K, Sawyer MH. Factors Associated With Missed Opportunities for Influenza Vaccination: Review of Medical Records in a Diverse Sample of Primary Care Clinics, San Diego County, 2010-2011. J Prim Care Community Health. 2014 Nov 27. pii: 2150131914559541.
Ly E, Peddecord M, Wang W, Ralston K, Sawyer MH. Using academic detailing to improve childhood influenza vaccination rates in San Diego. Public Health Rep. 2015: 130(2):179-187
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Clinical Guidelines
Schillie S, Murphy TV, Sawyer M, Ly K, Hughes E, Jiles R, de Perio MA, Reilly M, Byrd K, Ward JW; Centers for Disease Control and Prevention (CDC). CDC guidance for evaluating health-care personnel for hepatitis B virus protection and for administering postexposure management. MMWR 2013; 62 (RR-10):1-19.
Bradley JS, Peacock G, Krug SE, Bower WA, Cohn AC, Meaney-Delman D, Pavia AT; Committee on Infectious Diseases and Disaster Preparedness Advisory Council. Pediatric anthrax clinical management. Pediatrics. 2014 May;133(5):e1411-36. doi: 10.1542/peds.2014-0563. PubMed PMID: 24777226.
American Academy of Pediatrics Committee on Infectious Diseases. Updated recommendations on the use of meningococcal vaccines. Pediatrics. 2014Aug;134(2):400-3. doi: 10.1542/peds.2014-1383.
American Academy of Pediatrics Committee on Infectious Diseases; American Academy of Pediatrics Bronchiolitis Guidelines Committee. Updated guidance for palivizumab prophylaxis among infants and young children at increased risk of hospitalization for respiratory syncytial virus infection. Pediatrics. 2014, Aug;134(2):415-20. doi: 10.1542/peds.2014-1665.
Committee on Infectious Diseases; American Academy of Pediatrics. Recommendations for prevention and control of influenza in children, 2014-2015. Pediatrics. 2014 Nov;134(5):e1503-19. doi: 10.1542/peds.2014-2413. Epub 2014 Sep 22
Committee on Infectious Diseases: American Academy of Pediatrics. Immunization for Streptococcus pneumoniae Infections in High-Risk Children. Pediatrics. 2014 Dec;134(6):1230-3. doi: 10.1542/peds.2014-2811.
Starke JR; Committee on Infectious Diseases: American Academy of Pediatrics Interferon-γ Release Assays for Diagnosis of Tuberculosis Infection and Disease in Children. Pediatrics. 2014 Dec;134(6):e1763-73. doi: 10.1542/peds.2014-2983
Orenstein WA; Committee on Infectious Diseases: American Academy of Pediatrics Eradicating Polio: How the World's Pediatricians Can Help Stop This Crippling Illness Forever. Pediatrics. 2015 Jan;135(1):196-202. doi:10.1542/peds.2014-3163.
Committee on Infectious Diseases: American Academy of Pediatrics. Recommended childhood and adolescent immunization schedule-United States, 2015. Pediatrics. 2015; 135(2):396-397
Panel on Treatment of HIV-Infected Pregnant Women and Prevention of Perinatal
Transmission. Recommendations for Use of Antiretroviral Drugs in Pregnant HIV-1-
Infected Women for Maternal Health and Interventions to Reduce Perinatal HIV
Transmission in the United States.
Available at http://aidsinfo.nih.gov/contentfiles/lvguidelines/PerinatalGL.pdf.
Kimberlin DW, Acosta EP, Prichard MN, Sánchez PJ, Ampofo K, Lang D, Ashouri N, Vanchiere JA, Abzug MJ, Abughali N, Caserta MT, Englund JA, Sood SK, Spigarelli MG, Bradley JS, Lew J, Michaels MG, Wan W, Cloud G, Jester P, Lakeman FD, Whitley RJ; for the National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group. Oseltamivir Pharmacokinetics, Dosing, and Resistance Among Children Aged <2 Years With Influenza. J Infect Dis. 2013 Mar;207(5):709-720.
Kaplan SL, Barson WJ, Ling-Lin P, Romero JR, Bradley JS, Tan TQ, Hoffman JA, Givner LB, Mason EO Jr. Early trends for invasive pneumococcal infections in children following the introduction of the 13-valent pneumococcal conjugate vaccine. Pediatr Infect Dis J. 2013 Mar;32(3)203-7.
Hulten KG, Kaplan SL, Lamberth LB, Barson WJ, Romero JR, Lin PL, Bradley JS, Givner LB, Tan TQ, Hoffman JA, Mason EO. Changes in Streptococcus pneumoniae Serotype 19A Invasive Infections in Children from 1993-2011. J Clin Microbiol. 2013 Apr;51(4):1294-7.
Le J, Bradley JS, Murray W, Romanowski GL, Tran TT, Nguyen N, Cho S, Natale S, Bui I, Tran TM, Capparelli EV. Improved Vancomycin Dosing in Children Using Area-Under-the-Curve Exposure. Pediatr Infect Dis J. 2013 Apr;32(4):e155-63.
Nieves D, Bradley JS, Gargas J, Mason WH, Lehman D, Lehman SM, Murray EL, Harriman K, Cherry JD. Exchange Blood Transfusion in the Management of Severe Pertussis in Young Infants. Pediatr Infect Dis J. 2013 Jun;32(6):698-9.
Committee on infectious diseases. Recommendations for prevention and control of influenza in children, 2013-2014. Pediatrics. 2013 Oct;132(4):e1089-104.
Bradley JS. Which antibiotic for resistant Gram-positives, and why? J Infect. 2014 Jan;68 Suppl 1:S63-75
Le J, Ngu B, Bradley JS, Murray W, Nguyen A, Nguyen L, Romanowski GL, Vo T, Capparelli EV. Vancomycin Monitoring in Children Using Bayesian Estimation. Ther Drug Monit. 2014 Jan 21. [Epub ahead of print]
Hendricks KA, Wright ME, Shadomy SV, Bradley JS, Morrow MG, Pavia AT, Rubinstein E, Holty JE, Messonnier NE, Smith TL, Pesik N, Treadwell TA, Bower WA; Workgroup on Anthrax Clinical Guidelines. Centers for disease control and prevention expert panel meetings on prevention and treatment of anthrax in adults. Emerg Infect Dis. 2014 Feb;20(2).
Samady W, Bush R, Pong A, Andrews A, Fisher ES. Predictors of Clostridium difficile infections in hospitalized children. J Hosp Med. 2014 Feb;9(2):94-8.
Bradley JS, Peacock G, Krug SE, Bower WA, Cohn AC, Meaney-Delman D, Pavia AT; AAP Committee on Infectious Diseases and Disaster Preparedness Advisory Council. Pediatric Anthrax Clinical Management: Executive Summary. Pediatrics. 2014 Apr 28. [Epub ahead of print]
Bradley JS, Peacock G, Krug SE, Bower WA, Cohn AC, Meaney-Delman D, Pavia AT; AAP Committee on Infectious Diseases and Disaster Preparedness Advisory Council. Pediatric Anthrax Clinical Management. Pediatrics. 2014 Apr 28. [Epub ahead of print]
Bradley JS, Kauffman RE, Balis DA, Duffy CM, Gerbino PG, Maldonado SD, Noel GJ. Assessment of Musculoskeletal Toxicity 5 Years after Therapy with Levofloxacin. Pediatrics. 2014 Jul;134(1):e146-53
Bradley JS, Benzinger D, Bokesch P, Jacobs R. Single-dose Pharmacokinetics of Daptomycin in Pediatric Patients 3-24 Months of Age. Pediatr Infect Dis J. 2014 Sep;33(9):936-9.
Samady W, Pong A, Fisher E. Risk factors for the development of Clostridium difficile infection in hospitalized children. Curr Opin Pediatr. 2014 Oct;26(5):568-72.
Le J, Ny P, Capparelli E, Lane J, Ngu B, Muus R, Romanowski G, Vo T, Bradley J. Pharmacodynamic Characteristics of Nephrotoxicity Associated with Vancomycin Use in Children. J Ped Infect Dis first published online November 3, 2014 doi:10.1093/jpids/piu110.
Adam JK, Varan AK, Pong AL, McDonald EC; Centers for Disease Control and Prevention (CDC). Notes from the field: fatal rat-bite fever in a child - San Diego County, California, 2013. MMWR Morb Mortal Wkly Rep. 2014 Dec 19;63(50):1210-1.
Bradley JS, Puttagunta S, Rubino CM, Blumer JL, Dunne M, Sullivan JE. Pharmacokinetics, Safety and Tolerability of Single Dose Dalbavancin in Children 12 through 17. Pediatr Infect Dis J. 2014 Dec 30. [Epub ahead of print]
Kaplan SL, Center KJ, Barson WJ, Ling-Lin P, Romero JR, Bradley JS, Tan TQ, Hoffman JA, Peters TR, Gurtman A, Scott DA, Trammel J, Gruber WC, Hulten KG, Mason EO. Multicenter Surveillance of Streptococcus pneumoniae Isolates from Middle Ear and Mastoid Cultures in the 13-Valent Pneumococcal Conjugate Vaccine Era. Clin Infect Dis. 2015 May 1;60(9):1339-45. doi: 10.1093/cid/civ067. Epub 2015 Feb 3.
Bernstein H, Bradley J, Byington C. Influenza 2014-2015: The Flu Season [online course]. PediaLink. http://bit.ly/fluseason1415. 4/15/2015.
Olarte L, Barson WJ, Barson RM, Lin PL, Romero JR, Tan TQ, Givner LB, Bradley JS, Hoffman JA, Hultén KG, Mason EO, Kaplan SL. Impact of the 13-Valent Pneumococcal Conjugate Vaccine on Pneumococcal Meningitis in US Children. Clin Infect Dis. 2015 May 13. pii: civ368. [Epub ahead of print]
Le J, Capparelli EV, Wahid U, Wu YS, Romanowski GL, Tran TM, Nguyen A, Bradley JS. Bayesian Estimation of Vancomycin Pharmacokinetics in Obese Children: Matched Case-Control Study. Clin Ther. 2015 May 29. pii: S0149-2918(15)00293-3. doi: 10.1016/j.clinthera.2015.05.006. [Epub ahead of print]
Cirillo I, Vaccaro N, Castaneda-Ruiz B, Redman R, Cossey V, Bradley JS, Allegaert K. An Open-Label Study to Evaluate the Single-Dose Pharmacokinetics, Safety, and Tolerability of Doripenem in Infants Less Than 12 Weeks Chronological Age. Antimicrob Agents Chemother. 2015 Aug;59(8):4742-9.
Arnold JC, Bradley JS. Osteoarticular Infections in Children. Infect Dis Clin North Am. 2015 Sep;29(3):557-74.
Committee on Infectious Diseases. Recommendations for Prevention and Control of Influenza in Children, 2015-2016. Pediatrics. 2015 Oct;136(4):792-808.
Cannavino CR, Castaneda-Ruiz B, Redman R, Go O, Cirillo I, Barauskas V, Senatorova G, Emeryk A, Bradley JS. Safety and Tolerability of Doripenem in Hospitalized Children With Complicated Intra-Abdominal Infection, Complicated Urinary Tract Infections and Pneumonia. Pediatr Infect Dis J. 2015 Nov;34(11):1264-7.
George H. Talbot, John H. Powers, Steven C. Hoffmann, for the Biomarkers Consortium of the Foundation for the National Institutes of Health CABP-ABSSSI and HABP-VABP Project Teams. Developing Outcomes Assessments as Endpoints for Registrational Clinical Trials of Antibacterial Drugs: 2015 Update From the Biomarkers Consortium of the Foundation for the National Institutes of Health. Clin Infect Dis. 2015 Dec 13. pii: civ927 [Epub ahead of print].