UCSD Altman Clinical and Translational Research Institute

The ACTRI is part of a national Clinical and Translational Science Award (CTSA) consortium created to accelerate laboratory discoveries into treatments for patients. The CTSA program is led by the National Institutes of Health's National Center for Advancing Translational Sciences (NCATS). Founded in 2010, the ACTRI now helps develop and manage nearly 200 clinical trials each year.

ACTRI Mission and Goals

Translational research involves moving knowledge and discovery gained from the basic sciences to its application in clinical and community settings. This concept is often summarized by the phrases "bench-to-bedside" and "bedside-to-community" research. The vision of the ACTRI is to translate scientific discoveries into improved health, and its mission is to provide resources, training and collaboration opportunities for UC San Diego scientists, health care providers and the community.

Visit the ACTRI Website

ACTRI Faculty Investigators


ACTRI provides infrastructure and support for basic, translational and clinical research throughout the San Diego region to bring discoveries from the laboratory to the bedside, and facilitates training and education of the next generation of researchers. ACTRI now has more than 1,500 members, with affiliations that stretch across UC San Diego (Schools of Medicine and Pharmacy) and San Diego State University (Schools of Public Health and Nursing) to the Sanford Burnham Prebys Medical Discovery Institute and the Salk Institute, to Rady Children’s Hospital and the VA San Diego Health Care System, to nonprofit and biotech/pharma. 

CHARM Collaboration Contact:  Adriana Tremoulet, MD, MAS  (Professor of Pediatrics)

CHARM ⬌ ACTRI Collaborations

CHARM receives support and guidance from the ACTRI in the advancement of new diagnostic and therapeutic platforms for antibiotic-resistant pathogens to clinical application. ACTRI expertise in clinical trial coordination, regulatory issues and advance clinical laboratory and genomic technologies inform our best practices in getting patient (and microbial strain) information of the highest quality to positively impact patient outcomes in the most expeditious manner possible.


Energizing "Bench to Bedside"

ACTRI provides assistance with proposal development, study design, regulatory issues and submissions, biostatistics and informatics, and offers ethics consultation, clinical trial coordination, genomics technologies, biorepository services, facilitation with an affiliated laboratory network. ACTRI interactive functional areas include the Center for Clinical Research (CCR); Education, Training, and Career Development (ETCD); Biomedical Informatics (BMI); Community Engagement (CE); Translational Research Alliance (TRA); Translational Research Technology (TRT); and Evaluation.