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CHARM Special Events

CHARM hosts conferences, symposia and other special events in various forms to gather people from all different geographical areas, disciplines or fields of study with a common goal of fighting the AMR crisis. CHARM believes these special events will expand knowledge and instigate finding solutions to this global crisis. Attendees will gain the benefits of fresh perspectives, opportunites for feedback, new insights, and establishment as an expert. Networking opportunites at all CHARM events lead to connections for collaborations, jobs, committee members. Join CHARM at our next event and expand your thinking outside your field to other areas of research.

Experimental Approaches for Treatment of Infectious Disease

CHARM Symposium at Experimental Biology 2021: Tuesday April 27th, 2021 2:00-3:30PM EST 

The COVID-19 pandemic highlights the need for development of novel anti-infective agents. Although academic researchers and the biopharmaceutical industry have quickly responded to develop candidate therapies to address COVID-19, an even larger infectious disease challenge remains largely unaddressed: antibiotic resistance. Each year in the US, 2.8 million people are infected with antibiotic-resistant pathogens; 35,000 die as a result of such infections. The 2014 UK Government Review on Antimicrobial Resistance concluded that, without a dramatic change in our response, antimicrobial resistance will result in 300 million premature deaths and up to $10 trillion in loss to the global economy by 2050, exceeding cancer as a cause of human mortality. Particularly at risk are patients already more vulnerable to illness from viral lung infections such as COVID-19; in fact, the CDC estimates that 29%-55% of the deaths recorded during the 2009 H1N1 influenza pandemic were caused by secondary bacterial pneumonia. Many major pharmaceutical companies have abandoned antibiotic R&D after judging it to be unprofitable, creating an innovation gap. Furthermore, because of frequent use of antibiotics for self-resolving issues, physician reliance on unnecessarily broad-spectrum regimes, widespread use of antibiotics in agricultural feed for growth promotion, and pure Darwinian evolution of bacteria, we face a dilemma where new anti-infective approaches are needed. This symposium highlights translational research efforts aimed at resolving this unmet medical need.

​Chairs:
Ericka Anderson, PhD
Managing Director, CHARM​
Ross Corriden, PhD
Associate Director, Neuron23​

Presenters:
​Lauren Bakaletz, PhD
Professor, Ohio State University College of Medicine
Founder, Scioto Biosciences
"​Targeting the Biofilm Matrix for Disruption Results in Newly Released (NRel) Bacteria with Markedly Increased Sensitivity to Traditional Antibiotics that are Otherwise ineffective Against Biofilms"

​Liangfang Zhang, PhD
Professor, UC San Diego​
​"Biomimetic Nanoparticles for the Treatment of Infectious Diseases​"
Lynette Cegelski, PhD
Associate Professor, Stanford University​
​"Vancomycin Conjugates Yield Extraordinary New Activities Against Gram-positive and Gram-negative Bacteria"

David Gonzalez, PhD
Assistant Professor, UC San Diego​ School of Medicine
​"Mortality Risk Profiling of Staphylococcus aureus Bacteremia by Multi-omic Serum Analysis Reveals Early Predictive and Pathogenic Signatures"​

AMRITA BIOCREST 2021

The overarching theme of this 3 day symposium is the imminent and pressing issue of Antimicrobial resistance (AMR). AMR signifies a metaphorical race between man and microbe; this ‘race of the century’ would certainly define the ways in which microbial infections will be managed and treated in the future. Concerted efforts involving academia, industry, policy makers and community is becoming vital in gaining an upMANship over ‘superBUGS’. This symposium aims to collate viewpoints and draw a road-map in the process that could serve as guidelines in prioritising collaboration, research focus, good-practices, community responsibilities and industry participation. This symposium will bring together world- renowned experts from across the globe representing academia and industry. A special segment called ‘India Innovative pavilion’ is included that highlights the AMR innovation work being done by the best companies from India, in Drug discovery, diagnostics and devices verticals. Talks, competitions (business pitch, poster and oral presentations, quiz, videography and photography), and a town hall meeting are the main features of the symposium.


Learn more and Register Here

Beating Superbugs: Can We Win?

A feature-length documentary which details the antimicrobial resistance crisis through first-hand victim's stories and dedicated experts in science, economics, government, and the pharmaceutical industry. It presents the nature of the threat (Superbugs) and a spectrum of interrelated solutions - the global economic, politcal, and pharmaceutical forces now aligning to help science stop this deadly global crisis.

Panel Discussion of Beating Superbugs

CHARM hosted panel discussion of Beating Superbugs: Can We Win? featuring Tufts University School of Medicine's Helen Boucher, MIT's James Collins, Harvard Medical School's Scott Podolsky, and Boston College's Muhammad Zaman. These experts talk through the most pressing questions and exciting new solutions on offer today.

Watch the panel for Free Here