Antiobiotic Resistant Pneumococcus
In the 1990's ~60,000 cases of invasive pneumococcal disease occured each year, with up to 40% caused by bacteria resistant to at least 1 antibiotic and increasingly becoming resistant to 3 or more antibiotic drug classes. In 1993 a pneumococcal vaccine was introduced with more than 90% efficacy in children under 5. After the introduction of this vaccine, cases of invasive disease decreased, antibiotic use was reduced, and the prevalence of AMR pneumococcus declined. In 2015, invasive disease was down to ~30,000 cases, with resistant bacteria in 30% of cases.