NIH funded study (R01) on the mechanisms of tissue remodeling in eosinophilic esophagitis (EoE) (the role of pro-inflammatory and pro-fibrotic molecules), diagnosis (biomarker discovery), and treatment options and their effects on disease complications such as esophageal remodeling
DOD funded study of the genetics of food allergic EoE
Executive Council member, The International Gastrointestinal Eosinophil Research Network
Editorial Board of Journal of Allergy and Clinical Immunology
New Grant: AAAAI/APFED HOPE Pilot Project in Eosinophilic Diseases
Jane C. Burns, MD
The pathophysiology, immunology, diagnosis, etiology, treatment, genetics, epidemiology and history of Kawasaki disease
A multicenter, randomized placebo-controlled clinical trial of infliximab plus IVIG for primary treatment of Kawasaki disease
Call-back study of adolescents and young adults with a history of Kawasaki disease in childhood
Johanna Chang, MD
Pediatric Joint Ultrasound
Coinvestigator on several CARRA clinical trials
Alessandra M. Franco, MD, PhD
T-cell repertoire in Kawasaki disease
Biological function of IVIG therapy
Immune-regulation in infants and young children
Cytotoxic T cell biology
Carbohydrate T cell recognition
Designer glycopeptides containing tumor-associated carbohydrate antigens as vaccines for prevention/treatment of epithelial cancer
Hal M. Hoffman, MD
Role of innate immunity and IL-1 therapy in autoinflammatory disorders
Characterization of cryopyrin inflammasome function using a number of experimental models, including in vitro cell lines, ex vivo monocytes and genetically modified mice
Genetic basis of rare inherited disorders including congenital diarrheas, rare urticarial, and immunodeficiency, and autoinflammatory disorders
Inflammatory mechanisms involved in periodic fever disorders of childhood
Stephanie Leonard, MD
Principle Investigator of Clinical trial at RCHSD site, for novel treatments of peanut allergy
Robert M. Sheets, MD
Clinical trials of new treatments for pediatric rheumatologic diseases including the TREAT study