COVID-19 Updates

Visit UC San Diego's Coronavirus portal for the latest information for the campus community.

Publications

Ali SS, Hsiao Y, Zhao HW, Dugan LL, Haddad GG, Zhou D. Hypoxia-adaptation involves mitochondrial metabolic depression and decreased ROS leakage. 2012. PLoS ONE, 7(5):e36801. PMID: 22574227.

Arnold JC, Cannavino CR, Ross MK, Westley B, Miller T, Riffenburg R, Bradley J. Acute Bacterial Osteoarticular Infections: Eight Year Review of Outcomes Using Oral Step-down Therapy. Manuscript 2012-0220. Pediatrics, vol 130, number 4, October 2012.

Azad P, Ryu J, Haddad GG, Distinct role of Hsp70 in drosophila hemocytes during severe hypoxia. Free Radical Biology and Medicine, 51(2): 530-538, 2011.

Azad P, Zhou D, Zarndt R, Haddad GG. Identification of genes underlying hypoxia tolerance in drosophila by a P-element screen. G3 (Bethesda). 2(10): 1169–1178, 2012. PMCID: PMC3464109

Azad P, Haddad GG. Genetic animal models of preconditioning. Transl Stroke Res, 4(1):51-55, 2013. PMCID:PMC3614364.

Cooper, JL, P Quinton, and S. Ballard 2013. Mucociliary transport in porcine trachea: differential effects of inhibiting chloride and bicarbonate secretion. Am J Physiol Lung Cell Mol Physiol, 304:L184-190.

Douglas, RM, Chen A, Iniguez A, Wang J, Fu Z, Powell FL Jr, Haddad G G, Yao H. Chemokine receptor-like 2 is involved in ischemic brain injury. J Exp Stroke Transl Med, 6:1-6, 2013. PMCID:PMC3705577.

Felfly H, Zambon AC, Xue J, Muotri A, Zhou D, Snyder E, Haddad GG. Severe hypoxia: Consequences to neural stem cells and neurons. Journal of Neurology Research, 1(5):177-189, 2011.

Felfly H, Xue J, Zambon AC, Muotri A, Zhou D, Haddad GG. Identification of a neuronal gene expression signature: role of cell-cycle arrest in murine neuronal differentiation in vitro. American Journal of Physiology Regulatory, Integrative and Comparative Physiology, 301(3):R727-45, 2011.

Felfly H, Haddad GG. Protection of mice from stroke using hematopoietic stem cell transplantation. Stem Cells and Cancer Stem Cells, Volume 3. Hayat MA, Ed. Springer, 2012, pp. 295-303.

Felfly H, Haddad GG. Hematopoietic Stem Cells: Potential New Applications for Translational Medicine. In: Hematopoietic Stem Cells: New Research, Nova Science Publishers, Inc. 2012, pp. 51-96.

Haddad GG. Development of the lung and respiratory system. In: Textbook of Clinical Pediatrics, 2nd Edition. Edited by AY Elzouki, HA Harfi and H Nazer, FB Stapleton, W Oh, RH Whitley. Springer, 2012, pp. 2125-2128.

Haddad GG. Pulmonary function testing. In: Textbook of Clinical Pediatrics, 2nd Edition. Edited by AY Elzouki, HA Harfi and H Nazer, FB Stapleton, W Oh, RH Whitley. Springer, 2012, pp. 2133-2135.

Haddad GG. The pathophysiology of cough. In: Textbook of Clinical Pediatrics, 2nd Edition. Edited by AY Elzouki, HA Harfi and H Nazer, FB Stapleton, W Oh, RH Whitley. Springer, 2012, pp. 2149-2151.

Haddad GG. Upper airway obstruction and hypoventilation during sleep. In: Textbook of Clinical Pediatrics, 2nd Edition. Edited by AY Elzouki, HA Harfi and H Nazer, FB Stapleton, W Oh, RH Whitley. Springer, 2012, pp. 2221-2224.

Haddad GG. Primary Ciliary Dyskinesia. In: Textbook of Clinical Pediatrics, 2nd Edition. Edited by AY Elzouki, HA Harfi and H Nazer, FB Stapleton, W Oh, RH Whitley. Springer, 2012, pp. 2225-2227.

Heinrichsen E, Haddad GG. Role of High-fat Diet in Stress Response in Drosophila. 2012. PLos ONE, 7(8):e42587. PMCID:PMC3411628.

Kinney HC, Rognum TO, Nattie EE, Haddad GG, Hyma B, McEntire B, Paterson DS, Crandall L, Byard RW. Sudden and Unexpected Death in Early Life: Proceedings of a Symposium in Honor of Dr. Henry F. Krous 2012. Forensic Science, Medicine and Pathology, 8(4):414-25 PMID:22941540.

Lesser DJ, Haddad GG, Bush RA, Pian MS. The utility of a portable recording device for screening of obstructive sleep apnea in obese adolescents. J. Clin Sleep Med, 8(3):271-7, 2012. PMCID:PMC3365085.

Mittal M, Gu XQ, Pak O, Pamenter ME, Haag D, Fuchs B, Schermuly RT, Ghofrani HA, Brandes RP, Seeger W, Grimminger F, Haddad GG, Weissmann N. Hypoxia induces Kv channel current inhibition by increased NADPH oxidase derived reactive oxygen species. Free Radical Biology & Medicine, 52(6):1033-42, 2012. PMID: 22222468.

Pamenter ME, Ali SS, Tang Q, Finley CJ, Gu X, Dugan LL, Haddad GG. An in vitro ischemic penumbral mimic perfusate increases NADPH oxidase-mediated superoxide production in cultured hippocampal neurons. 2011. Brain Res, 3;1452:165-72, 2012. PMCID:PMC3326196. Pamenter ME, Hogg DW, Gu XQ, Buck LT, Haddad GG. Painted turtle cortex is resistant to an in vitro mimic of the ischemic mammalian penumbra. J Cereb Blood Flow Metab, 32(11):2033- 43, 2012. PMCID: PMC3493991

Pamenter ME, Ryu J, Hua S, Perkins G, Mendiola V, Gu XQ, Ellisman MH, Haddad GG. 2012. DIDS prevents ischemic membrane degradation in cultured hippocampal neurons by inhibiting matrix metalloproteinase release. PLoS ONE, 7(8):e43995, 2012. PMCID: PMC3427179.

Pamenter ME, Perkins GA, McGinness AK, Gu XQ, Ellisman MG, Haddad GG. Autophagy and apoptosis are differentially induced in neurons and astrocytes treated with an in vitro mimic of the ischemic penumbra. PLoS ONE, 7(12):e51469, 2012. PMCID: PMC3520810.

Pamenter, M, Perkins, G, Gu, X, Ellisman, M, Haddad, G.G. DIDS (4,4-diisothiocyan atostilbenedisulphonic acid) induces apoptotic cell death in a hippocampal neuronal cell line and is not neuroprotective against ischemic stress. PLoS One, 8(4):e60804, 2013. PMCID:PMC3618322.

Perkins G, Hsiao YH, Yin S, Tjong J, Tran MT, Lau J, Xue J, Liu S, Ellisman MH, Zhou D. Ultrastructural modifications in the mitochondria of hypoxia-adapted Drosophila melanogaster. PLoS One, 7(9):e45344, 2012.

Powell F, Heldt G, Haddad GG. Chapter 41: Respiratory Physiology. Rogers¹ Textbook of Pediatric Critical Care, 2013 in press.

Quinton P, Molyneux M, Ip W, Dupuis A, Avolio J, Tullis E, Conrad D, Shamsuddin AK, Durie P, Gonska T. Beta-adrenergic Sweat Secretion as a Diagnostic Test for Cystic Fibrosis. Am J Respir Crit Care Med., 186 : 732–739, 2012.

Riordan J, Boucher R, Quinton PM. Eds. Cystic Fibrosis: A Trilogy of Biochemistry, Physiology, and Therapy. Cold Spring Harbor Laboratory Press, 340 pages, 2013.

Sieck GC, Haddad GG, Lucchesi P. Physiology’s impact: discovering life. Physiology (Bethesda), 28(2):62-3, 2013.

Shamsuddin, AK, and PM Quinton. 2012. Surface fluid absorption and secretion in small airways. J Physiol, 590:3561-3574, 2012.

Stucky E, Haddad GG. Respiratory Failure. In: Textbook of Clinical Pediatrics, 2nd Edition. Edited by AY Elzouki, HA Harfi and H Nazer, FB Stapleton, W Oh, RH Whitley. Springer, 2012, pp. 2141-2148.

Udpa N, Zhou D, Haddad GG, Bafna V. Tests of selection in pooled case-control data: An empirical study. Front Genet, 2011. 2:83 PMCID: PMC3268381.

Xie L, Ali T, Valencia R, Ferreira BL, Xue V, Tanweer M, Zhou D, Haddad GG, Bourne PE, Xie L. Multiscale Modeling of the Causal Functional Roles of nsSNPs in a Genome-Wide Association Study: Application to Hypoxia. 2013. BMC Genomics, 14 Suppl 3:S9 PMCID:PMC3665574.

Yin SY, Xue J, Sun HD, Wen B, Wang QH, Perkins G, Zhao HW, Ellisman MH, Hsiao Y, Yin L, Xie YY, Zi J, Lin L, Haddad GG, Zhou D, Liu SQ (2013). Quantitative Evaluation of the Mitochondrial Proteomes of Drosophila melanogaster Adapted to Extreme Oxygen Conditions" PLoS ONE. in press.

Zhao HW, Ali SS, Haddad GG. Does hyperoxia selection cause adaptive alterations of mitochondrial electron transport chain activity leading to a reduction of superoxide production? Antioxidants & Redox Signaling, 16(10):1071-6, 2012. PMCID:PMC3315163

Zhou, D, Udpa N, Gersten M, Visk DW, Bashir A, Xue J, Frazer K, Posakony J, Subramaniam S, Bafna V, Haddad GG. Experimental Selection of Hypoxia-tolerant Drosophila melanogaster. Proc Natl Acad Sci USA, 108(6): 2349-2354, 2011.

Zhou D, Udpa N, Ronen R, Stobdan T, Liang J, Appenzeller O, Zhao H, Yin Y, Du Y, Gu L, Cao R, Wang Y, Jin X, Huang C, Jia W, Cao D, Guo G, Gamboa J, Villafuerte F, Callacond D, Xue J, Liu S, Frazer K, Li Y, Bafna V, Haddad GG. Whole-Genome Sequencing Uncovers the Genetic Basis of Chronic Mountain Sickness in Andean Highlanders. The American Journal of Human Genetics, 93:1–11, 2013. Zhou D, Haddad GG. Genetic Analysis of Hypoxia Tolerance and Susceptibility in Drosophila and Humans. Annu Rev Genomics Hum Genet, 2013 Jun 26 PMID:23808366.