Dr. Shelley M. Lawrence is a federally funded Associate Clinical Professor at UCSD, Department of Pediatrics, Division of Neonatal-Perinatal Medicine (NPM), and Program Director of the NPM Fellowship. She has been a practicing neonatologist at UCSD Jacobs and Hillcrest Medical Centers and the Rady Children’s Hospital of San Diego since 2014, but has nearly 20 years of NPM experience in both private and academic medical centers. She received her Master of Science degree in Clinical and Translational Sciences in 2013 and has published over 20 primary science manuscripts, reviews, and book chapters, collectively cited over 170 times. She has directly mentored fellows, residents, medical students, PhD candidates, Master of Science students, and graduate students over the last 10 years.
Lab Focus: Neutrophil Activation and Innate Immune Function
Her research interests lie in (1) investigating novel pathways and mechanisms (including other types of pharmaceutical agents) to treat infectious disease, (2) understanding the pathogenesis of sepsis and fundamental mechanisms employed by the neonatal innate immune system to combat infectious organisms, with particular focus on neonatal neutrophil function (3) translating innovative technologies that can rapidly and accurately identify and quantitate pathogens that cause neonatal sepsis, thereby facilitating the immediate administration of targeted antimicrobials. She is currently collaborating with Dr. Victor Nizet and Dr. Liangfang Zhang on the translation of host cell membrane-coated nanoparticle technologies as adjuvant therapy for the treatment of neonatal septic shock and necrotizing enterocolitis. She is also collaborating with Dr. Stephanie Fraley on the translation of an innovative pathogen detection platform, termed "NeoChip", for the inexpensive, rapid, and accurate detection of pathogens (fungal, bacterial, and viral) in low volume tissue matrices to facilitate the immediate administration of targeted antimicrobials and therapeutics.
For more information about the Lawrence lab, please visit http://nizetlab.ucsd.edu/people/Shelley .