COVID-19 Updates

Visit UC San Diego's Coronavirus portal for the latest information for the campus community.

Ongoing Clinical Research

One of the primary goals of our division and the shared vision of all our faculty and staff is to provide better care, health, and outcomes for infants. To promote this goal, we support a range of investigator initiated and sponsor initiated research focused on improving health for infants today and tomorrow.  This research includes everything from case studies and chart reviews to multicenter, interdisciplinary clinical trials.  

From bench to bedside, around the world and back, our research has included both internal and external collaborators.  Internal collaborators have included bioengineering, cardiology, genomics, infectious disease, neurology, opthamology, and more.  On a national and international level, we have been involved in clinical trials on IV Tylenol, cooling on transport, levetiracetam (an anti-seizure medication), IV nutrition, antibiotic safety, and more.  Funding for our projects has come from the NIH, NICHD, the Thrasher Foundation, the Rady Children’s Hospital Foundation, and various industry sponsors among others.

Our current division projects include the following:


Prospective Review of Extracorporeal Membrane Oxygenation (ECMO) Treatment, Complications, and Outcomes | PI:  Denise Suttner

Study of Attitudes and Factors Effecting PREterm infant care Practices (SAFE PREP) – Phase II | PI:  Erika Fernandez

National Registry for Surveillance and Epidemiology of Perinatal COVID-19 Infection | PI: Laurel Moyer

Interviewing Spanish Speaking Parents about Communication in the NICU | PI: Krishelle Marc-Aurele

NeoChip Scavenged Cord Blood – NeoChip testing and validation utilizing scavenged neonatal cord blood samples (Collaboration with bioengineering) | PI: Shelley Lawrence

Pharmacokinetics and Safety Profile of Digoxin in Infants with Single Ventricle Congenital Heart Disease (Multicenter study with the NICHD Pediatric Trials Network / Duke Clinical Research Institute) | PI: Denise Suttner

Utilizing scavenged complete blood count samples for NeoChip testing and validation  | PI: Shelley Lawrence (Collaboration with bioengineering)

NeoChip: High Resolution Melt with machine learning for the accurate and rapid diagnosis of sepsis in neonates (Collaboration with bioengineering) | PI: Shelley Lawrence

Electrophysiology of the gut and the microbiome in high-risk neonates | PI: Lance Prince (Collaboration with bioengineering)

Study of oligosaccharides on the surface of human blood cells and inflammatory and microbicidal proteins in whole blood | PI: Shelley Lawrence

Additionally, the following projects are collaborations with other divisions, currently recruiting/enrolling in the UCSD and RCHSD NICU(s):


VGFTe-ROP - Randomized, Controlled, Multi-Center Study to Assess the Efficacy, Safety, and Tolerability of Intravitreal Aflibercept Compared to Laser Photocoagulation in Patients with Retinopathy of Prematurity | PI: Eric Nudleman (Opthamology)

“PROPER”: Partnership for retinopathy of prematurity evaluation in the real world (PROPER) consortium | PI: Eric Nudleman (Opthamology) 

A Multi-Center Randomized Trial of Transanastomotic Tube for Proximal Esophageal Atresia with Distal Tracheoesophageal Fistula Repair | PI: David Lazar (Surgery)

A simple method of detecting neurologic disease in the neonate and young child | PI: Jeff Gold (Neurology)

“CAZ-AVI”: A Phase 2A, 2-Part, Open-Label, Non-randomized, multicenter, single and multiple dose trial to evaluate pharmacokinetics, safety and tolerability of ceftazidime and avibactam in neonates and infants from birth to less than 3 months of age with suspected or confirmed infections due to gram-negative pathogens requiring intravenous antibiotic treatment | PI: John Bradley (Infectious Disease)

 “MAP”: The Association Between Milk Feedings in the Preterm Population, the Microbiome, and the Risk of Atopic Disease | PI: Sydney Leibel (Allergy & Immunology), Co-I: Sandra Leibel

Mommy’s Milk – Human Milk Biorepository | https://mommysmilkresearch.org/

Show additional content areas below