CHARM ⬌ LRF MoMI Core Collaborations
CHARM and LRF MoMI Core Investigators and studying the impact of human milk in term and preterm infants with respect to both short- and long-term effects on health and disease. Human milk, its special oligosaccharide composition, and its transferred antibodies shape the infant microbiome and metabolome, boost host immunity and epithelial barrier integrity, and afford protection against infectious diarrhea, ear infections, and urinary tract infections. Indeed, direct antimicrobial effects of human milk on certain newborn bacterial pathogens have recently been uncovered.