CHARM ↔ Division of HMS&T Collaborations
CHARM Faculty in the Division of HMS&T are seeking therapies for drug-resistant pathogens afrom genome-driven high throughput chemical biology screens, systems biology approaches, targeted neutralization of virulence phenotypes, pharmacologic augmentation of host innate immune functions, modulation of host inflammatory responses, reversal of antimicrobial resistance phenotypes and prophylactic vaccines. Likewise, we are exploring links between the human microbiome and infection susceptibililty to inspire novel diagnostic, preventative and therapeutic interventions.