The Gonias Lab is particularly interested in the function of protease receptors in cancer and inflamation but also has active projects related to peripheral nerve injury, Alzheimer’s disease, and vascular biology. In each of these areas, the role of inflammatory cells and their regulation by proteases is important to us. Our researchers apply diverse and advanced approaches to address scientific problems, including transgenic and spontaneous malignancy mouse model systems, mass spectrometry/proteomics, and high resolution imaging. We take full advantage of a rich and collaborative scientific community at UC San Diego. Close collaborators include Dr. Wendy Campana, Dr. Richard Klemke, and Dr. David Cheresh.
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