Faculty Labs - Research Programs

Division of Gynecologic Oncology

  • Schlepfer Lab - Our lab's goal is to understand how cancers spread from their tissue of origin to other sites in the body. Our research interests are focused upon the molecular signaling events that control cell migration and survival. We hypothesize that there are important intracellular signaling proteins that act to integrate and regulate both motility and survival signals within cells
  • Stupack Lab

Division of Maternal-Fetal Medicine

  • Laurent Lab - Our lab applies our expertise in human pluripotent stem cell research and genomics to understand the molecular mechanisms underlying normal and abnormal human development, in order to improve the health of mothers and babies.
  • Natale Lab - The Natale Lab uses mouse trophoblast stem cells and models of placental insufficiency to understand how the placenta develops and functions to support a healthy pregnancy

Division of Reproductive Endocrinology and Infertility

  • The Center for Reproductive Science and Medicine - The goal of the Center for Reproductive Science and Medicine at UC San Diego is to develop understanding of the fundamental mechanisms that cause disordered function of the hypothalamic-pituitary-ovarian axis in Polycystic Ovary Syndrome (PCOS). Polycystic ovary syndrome (PCOS) is the most common cause of female infertility, occurring in about 1 in 10 women of childbearing age.
  • Breen Church Lab - The Breen Church lab focuses on: Neuroendocrine mechanisms controlling reproduction and fertility; Mechanisms underlying stress and stress-associated disease states on fertility; and Early life programming of delayed or deficient fertility.
  • Cook-Andersen Lab - The Cook-Anderson Lab is interested in: post-transcriptional regulation of gene expression; transcriptional silencing in the oocyte and oocyte maturation; early embryo development and embryonic genome activation, nuclear repromamming, the molecular basis of ovarian aging
  • Duleba Lab
  • Kauffman Lab - We use a variety of molecular, cellular, physiological and neuroanatomical techniques to study how the brain and hormones interact to control reproduction in mammals. More specifically, we assess how neural circuits stimulate or inhibit Gonadotropin-releasing hormone (GnRH) neurons, thereby regulating the neuroendocrine reproductive axis.
  • Lawson Lab - The main focus of the Lawson Laboratory is on understanding how the brain and pituitary interpret and respond to the various signals that control reproductive hormone synthesis and secretion.
  • Mellon Lab - We are interested in how the brain controls reproduction through the neuroendocrine system with emphases on development, hormone signaling, gene expression, circadian rhythm, and mouse models of human disease.
  • Shimasaki Lab
  • Thackray Lab - The focus of our research is to understand the etiology and pathophysiology of PCOS using relevant mouse and tissue culture models. We are currently studying the influence of genetic variation on gonadotropin hormone production and fertility. We are also investigating interactions among metabolism, the gut microbiome and the reproductive axis in PCOS.
  • Wilkinson Lab - Our studies are centered on the impact of gene regulatory circuits in normal development and disease.