Vineet Bafna, Ph.D.
Professor, Computer Science Department
Institute for Genomic Medicine
UC San Diego
Dr. Bafna's role in this project is to lead the Bioinformatics Core. Specifically, he will develop and support the pipeline for analysis of Next Generation Sequencing (NGS), and exome sequencing data for the detection of variants associated with specific phenotypes.
Part of this will require the development of large data storage, organization and retrieval methods for NGS, and part will require the development of new algorithms for data analysis, variant prioritization, interrogation of newly emerged datasets, and methodology for validation of putative mutations within a functional mechanistic framework.