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Neurodegenerative Disorders on Guam

In the 1940s, ALS and Parkinson-Dementia-Complex (called Lytico-Bodig) were found to occur commonly in the Chamorro people of Guam. The incidence of ALS and PDC peaked in the 1950s, and fell in the next 5 decades.

Genetic and environmental causes have been suggested, but none are proven. Since 1997, researchers of 6 University Medical Centers across the USA have collaborated to reinvestigate these puzzling disorders.

brain synaps