Please contact Jennifer Santini if you have a recent publication from work performed in the core so it can be added to this list.
Zhao, Y., et al. Antigen-Presenting Cell-Intrinsic PD-1 Neutralizes PD-L1 in cis to Attenuate PD-1 Signaling in T Cells. Cell Rep 24, 379-390 e376 (2018).
Yan, J., et al. Histone H3 lysine 4 monomethylation modulates long-range chromatin interactions at enhancers. Cell Res 28, 204-220 (2018).
Veevers, J., et al. Cell-Surface Marker Signature for Enrichment of Ventricular Cardiomyocytes Derived from Human Embryonic Stem Cells. Stem Cell Reports 11, 828-841 (2018).
Sugie, J., Intaglietta, M. & Sung, L.A. Water transport and homeostasis as a major function of erythrocytes. Am J Physiol Heart Circ Physiol 314, H1098-H1107 (2018).
Stroud, M.J., et al. Luma is not essential for murine cardiac development and function. Cardiovasc Res 114, 378-388 (2018).
Schaffer, A.E., et al. Biallelic loss of human CTNNA2, encoding alphaN-catenin, leads to ARP2/3 complex overactivity and disordered cortical neuronal migration. Nat Genet 50, 1093-1101 (2018).
Ramdani, G., et al. cGMP-dependent protein kinase-2 regulates bone mass and prevents diabetic bone loss. J Endocrinol 238, 203-219 (2018).
Patel, A., et al. AxonTracer: a novel ImageJ plugin for automated quantification of axon regeneration in spinal cord tissue. BMC Neurosci 19, 8 (2018).
Narang, A. & Zheng, B. To Scar or Not to Scar. Trends Mol Med 24, 522-524 (2018).
Meves, J.M., Geoffroy, C.G., Kim, N.D., Kim, J.J. & Zheng, B. Oligodendrocytic but not neuronal Nogo restricts corticospinal axon sprouting after CNS injury. Exp Neurol 309, 32-43 (2018).
McCall, L.I., et al. Experimental Chagas disease-induced perturbations of the fecal microbiome and metabolome. PLoS Negl Trop Dis 12, e0006344 (2018).
Marin-Valencia, I., et al. A homozygous founder mutation in TRAPPC6B associates with a neurodevelopmental disorder characterised by microcephaly, epilepsy and autistic features. J Med Genet 55, 48-54 (2018).
Kyriakakis, P., et al. Biosynthesis of Orthogonal Molecules Using Ferredoxin and Ferredoxin-NADP(+) Reductase Systems Enables Genetically Encoded PhyB Optogenetics. ACS Synth Biol 7, 706-717 (2018).
Kalyanaraman, H., et al. Protein Kinase G Activation Reverses Oxidative Stress and Restores Osteoblast Function and Bone Formation in Male Mice With Type 1 Diabetes. Diabetes 67, 607-623 (2018).
Huang, M.L., et al. Small Molecule Antagonist of Cell Surface Glycosaminoglycans Restricts Mouse Embryonic Stem Cells in a Pluripotent State. Stem Cells 36, 45-54 (2018).
Holland, N.D. Formation of the initial kidney and mouth opening in larval amphioxus studied with serial blockface scanning electron microscopy (SBSEM). Evodevo 9, 16 (2018).
Friedman, B., et al. Detection of Subclinical Arthritis in Mice by a Thrombin Receptor-Derived Imaging Agent. Arthritis Rheumatol 70, 69-79 (2018).
De La Zerda, D.J., et al. Ibuprofen does not reverse ventilatory acclimatization to chronic hypoxia. Respir Physiol Neurobiol 256, 29-35 (2018).
Clark, A.E., Sabalza, M., Gordts, P. & Spector, D.H. Human Cytomegalovirus Replication Is Inhibited by the Autophagy-Inducing Compounds Trehalose and SMER28 through Distinctively Different Mechanisms. J Virol 92(2018).
Chen, M., et al. Leucine Zipper-Bearing Kinase Is a Critical Regulator of Astrocyte Reactivity in the Adult Mammalian CNS. Cell Rep 22, 3587-3597 (2018).
Breuss, M.W., et al. Mutations in LNPK, Encoding the Endoplasmic Reticulum Junction Stabilizer Lunapark, Cause a Recessive Neurodevelopmental Syndrome. Am J Hum Genet 103, 296-304 (2018).
Baumgartel, K., et al. PDE4D regulates Spine Plasticity and Memory in the Retrosplenial Cortex. Sci Rep 8, 3895 (2018).
Zhu, Y., et al. Comprehensive characterization of neutrophil genome topology. Genes Dev 31, 141-153 (2017).
Zhu, W., et al. Direct 3D bioprinting of prevascularized tissue constructs with complex microarchitecture. Biomaterials 124, 106-115 (2017).
Xu, X.S., Gantz, V.M., Siomava, N. & Bier, E. CRISPR/Cas9 and active genetics-based trans-species replacement of the endogenous Drosophila kni-L2 CRM reveals unexpected complexity. Elife 6(2017).
Wree, A., et al. NLRP3 inflammasome driven liver injury and fibrosis: Roles of IL-17 and TNF in mice. Hepatology (2017).
Warner, J.J., et al. 3D-printed biomaterials with regional auxetic properties. J Mech Behav Biomed Mater 76, 145-152 (2017).
van Vliet, P.P., et al. Tissue specific requirements for WNT11 in developing outflow tract and dorsal mesenchymal protrusion. Dev Biol 429, 249-259 (2017).
Stroud, M.J., et al. Nesprin 1alpha2 is essential for mouse postnatal viability and nuclear positioning in skeletal muscle. J Cell Biol 216, 1915-1924 (2017).
Song, Y., et al. Single-Cell Alternative Splicing Analysis with Expedition Reveals Splicing Dynamics during Neuron Differentiation. Mol Cell 67, 148-161 e145 (2017).
Rocca, C.J., et al. Transplantation of wild-type mouse hematopoietic stem and progenitor cells ameliorates deficits in a mouse model of Friedreich's ataxia. Sci Transl Med 9(2017).
Onishi, K. & Zou, Y. Sonic Hedgehog switches on Wnt/planar cell polarity signaling in commissural axon growth cones by reducing levels of Shisa2. Elife 6(2017).
Marin-Valencia, I., et al. Homozygous Mutations in TBC1D23 Lead to a Non-degenerative Form of Pontocerebellar Hypoplasia. Am J Hum Genet 101, 441-450 (2017).
Ly, P., et al. Selective Y centromere inactivation triggers chromosome shattering in micronuclei and repair by non-homologous end joining. Nat Cell Biol 19, 68-75 (2017).
Liao, Z., Kasirer-Friede, A. & Shattil, S.J. Optogenetic interrogation of integrin alphaVbeta3 function in endothelial cells. J Cell Sci 130, 3532-3541 (2017).
Lardelli, R.M., et al. Biallelic mutations in the 3' exonuclease TOE1 cause pontocerebellar hypoplasia and uncover a role in snRNA processing. Nat Genet 49, 457-464 (2017).
Lagarrigue, F., Gertler, F.B., Ginsberg, M.H. & Cantor, J.M. Cutting Edge: Loss of T Cell RIAM Precludes Conjugate Formation with APC and Prevents Immune-Mediated Diabetes. J Immunol 198, 3410-3415 (2017).
Koyanagi, T., et al. Thiol-Triggered Release of Intraliposomal Content from Liposomes Made of Extremophile-Inspired Tetraether Lipids. Bioconjug Chem 28, 2041-2045 (2017).
Kalyanaraman, H., et al. A Novel, Direct NO Donor Regulates Osteoblast and Osteoclast Functions and Increases Bone Mass in Ovariectomized Mice. J Bone Miner Res 32, 46-59 (2017).
Hirai, M., et al. Adaptor proteins NUMB and NUMBL promote cell cycle withdrawal by targeting ERBB2 for degradation. J Clin Invest 127, 569-582 (2017).
Guimaraes-Camboa, N., et al. Pericytes of Multiple Organs Do Not Behave as Mesenchymal Stem Cells In Vivo. Cell Stem Cell 20, 345-359 e345 (2017).
Gorshkov, K., et al. AKAP-mediated feedback control of cAMP gradients in developing hippocampal neurons. Nat Chem Biol 13, 425-431 (2017).
Geoffroy, C.G., Meves, J.M. & Zheng, B. The age factor in axonal repair after spinal cord injury: A focus on neuron-intrinsic mechanisms. Neurosci Lett 652, 41-49 (2017).
DeBoever, C., et al. Large-Scale Profiling Reveals the Influence of Genetic Variation on Gene Expression in Human Induced Pluripotent Stem Cells. Cell Stem Cell 20, 533-546 e537 (2017).
Chiang, W.C., et al. Achromatopsia mutations target sequential steps of ATF6 activation. Proc Natl Acad Sci U S A 114, 400-405 (2017).
Chaikeeratisak, V., et al. The Phage Nucleus and Tubulin Spindle Are Conserved among Large Pseudomonas Phages. Cell Rep 20, 1563-1571 (2017).
Campana, W.M., et al. Ionotropic glutamate receptors activate cell signaling in response to glutamate in Schwann cells. FASEB J 31, 1744-1755 (2017).
Burgdorf, J., et al. IGFBP2 Produces Rapid-Acting and Long-Lasting Effects in Rat Models of Posttraumatic Stress Disorder via a Novel Mechanism Associated with Structural Plasticity. Int J Neuropsychopharmacol 20, 476-484 (2017).
Brunsing, R.L., et al. Restriction spectrum imaging: An evolving imaging biomarker in prostate MRI. J Magn Reson Imaging 45, 323-336 (2017).
Blondelle, J., Shapiro, P., Domenighetti, A.A. & Lange, S. Cullin E3 Ligase Activity Is Required for Myoblast Differentiation. J Mol Biol 429, 1045-1066 (2017).
Bett, C., et al. Enhanced neuroinvasion by smaller, soluble prions. Acta Neuropathol Commun 5, 32 (2017).
Bertin, S., et al. The TRPA1 ion channel is expressed in CD4+ T cells and restrains T-cell-mediated colitis through inhibition of TRPV1. Gut 66, 1584-1596 (2017).
Benitez, J.A., et al. PTEN regulates glioblastoma oncogenesis through chromatin-associated complexes of DAXX and histone H3.3. Nat Commun 8, 15223 (2017).
Akassoglou, K., et al. In Vivo Imaging of CNS Injury and Disease. J Neurosci 37, 10808-10816 (2017).
Zhao, J.J. & Afshari, N.A. Generation of Human Corneal Endothelial Cells via In Vitro Ocular Lineage Restriction of Pluripotent Stem Cells. Invest Ophthalmol Vis Sci 57, 6878-6884 (2016).
Zaki, M.S., et al. PYCR2 Mutations cause a lethal syndrome of microcephaly and failure to thrive. Ann Neurol 80, 59-70 (2016).
Zaidi, F.N., et al. Innervation of taste buds revealed with Brainbow-labeling in mouse. J Anat 229, 778-790 (2016).
Yao, H., et al. The Na(+)/HCO3(-) co-transporter is protective during ischemia in astrocytes. Neuroscience 339, 329-337 (2016).
Yamin, G., et al. Voxel Level Radiologic-Pathologic Validation of Restriction Spectrum Imaging Cellularity Index with Gleason Grade in Prostate Cancer. Clin Cancer Res 22, 2668-2674 (2016).
Wang, L., et al. Intestinal REG3 Lectins Protect against Alcoholic Steatohepatitis by Reducing Mucosa-Associated Microbiota and Preventing Bacterial Translocation. Cell Host Microbe 19, 227-239 (2016).
Wang, L., Conner, J.M., Nagahara, A.H. & Tuszynski, M.H. Rehabilitation drives enhancement of neuronal structure in functionally relevant neuronal subsets. Proc Natl Acad Sci U S A 113, 2750-2755 (2016).
Vogl, C., et al. Tryptophan-rich basic protein (WRB) mediates insertion of the tail-anchored protein otoferlin and is required for hair cell exocytosis and hearing. EMBO J 35, 2536-2552 (2016).
Venugopalan, P., et al. Transplanted neurons integrate into adult retinas and respond to light. Nat Commun 7, 10472 (2016).
Suzuki, K., et al. In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration. Nature 540, 144-149 (2016).
Scully, K.M., et al. Epithelial cell integrin beta1 is required for developmental angiogenesis in the pituitary gland. Proc Natl Acad Sci U S A 113, 13408-13413 (2016).
Rosti, R.O., et al. Extending the mutation spectrum for Galloway-Mowat syndrome to include homozygous missense mutations in the WDR73 gene. Am J Med Genet A 170A, 992-998 (2016).
Roosing, S., et al. Mutations in CEP120 cause Joubert syndrome as well as complex ciliopathy phenotypes. J Med Genet 53, 608-615 (2016).
Robinson, J.E., Paluch, J., Dickman, D.K. & Joiner, W.J. ADAR-mediated RNA editing suppresses sleep by acting as a brake on glutamatergic synaptic plasticity. Nat Commun 7, 10512 (2016).
Meves, J.M. & Zheng, B. Synaptic Suppression of Axon Regeneration. Neuron 92, 267-269 (2016).
Metz, P.J., et al. Regulation of Asymmetric Division by Atypical Protein Kinase C Influences Early Specification of CD8(+) T Lymphocyte Fates. Sci Rep 6, 19182 (2016).
Mann, A.P., et al. A peptide for targeted, systemic delivery of imaging and therapeutic compounds into acute brain injuries. Nat Commun 7, 11980 (2016).
Ma, X., et al. Deterministically patterned biomimetic human iPSC-derived hepatic model via rapid 3D bioprinting. Proc Natl Acad Sci U S A 113, 2206-2211 (2016).
Ma, H.Y., et al. The role of IL-17 signaling in regulation of the liver-brain axis and intestinal permeability in Alcoholic Liver Disease. Curr Pathobiol Rep 4, 27-35 (2016).
Ma, F., et al. A Mouse Model for Dietary Xenosialitis: ANTIBODIES TO XENOGLYCAN CAN REDUCE FERTILITY. J Biol Chem 291, 18222-18231 (2016).
Lin, S.Y., et al. The zebrafish pinball wizard gene encodes WRB, a tail-anchored-protein receptor essential for inner-ear hair cells and retinal photoreceptors. J Physiol 594, 895-914 (2016).
Li, H., et al. Zika Virus Infects Neural Progenitors in the Adult Mouse Brain and Alters Proliferation. Cell Stem Cell 19, 593-598 (2016).
Lange, S., et al. MLP and CARP are linked to chronic PKCalpha signalling in dilated cardiomyopathy. Nat Commun 7, 12120 (2016).
Hope, T.R., et al. Demonstration of Non-Gaussian Restricted Diffusion in Tumor Cells Using Diffusion Time-Dependent Diffusion-Weighted Magnetic Resonance Imaging Contrast. Front Oncol 6, 179 (2016).
Hirai, M., Chen, J. & Evans, S.M. Tissue-Specific Cell Cycle Indicator Reveals Unexpected Findings for Cardiac Myocyte Proliferation. Circ Res 118, 20-28 (2016).
Grover, D., Katsuki, T. & Greenspan, R.J. Flyception: imaging brain activity in freely walking fruit flies. Nat Methods 13, 569-572 (2016).
Geoffroy, C.G., Hilton, B.J., Tetzlaff, W. & Zheng, B. Evidence for an Age-Dependent Decline in Axon Regeneration in the Adult Mammalian Central Nervous System. Cell Rep 15, 238-246 (2016).
Gao, M.H., et al. One-time injection of AAV8 encoding urocortin 2 provides long-term resolution of insulin resistance. JCI Insight 1, e88322 (2016).
den Hartog, G., et al. Regulation of Rac1 and Reactive Oxygen Species Production in Response to Infection of Gastrointestinal Epithelia. PLoS Pathog 12, e1005382 (2016).
de Jong, P.R., et al. ERK5 signalling rescues intestinal epithelial turnover and tumour cell proliferation upon ERK1/2 abrogation. Nat Commun 7, 11551 (2016).
Cohen, M., et al. Synthetic Mucus Nanobarriers for Identification of Glycan-Dependent Primary Influenza A Infection Inhibitors. ACS Cent Sci 2, 710-714 (2016).
Cividini, F., et al. O-GlcNAcylation of 8-Oxoguanine DNA Glycosylase (Ogg1) Impairs Oxidative Mitochondrial DNA Lesion Repair in Diabetic Hearts. J Biol Chem 291, 26515-26528 (2016).
Chen, M., et al. Leucine Zipper-bearing Kinase promotes axon growth in mammalian central nervous system neurons. Sci Rep 6, 31482 (2016).
Boogerd, C.J., et al. Probing chromatin landscape reveals roles of endocardial TBX20 in septation. J Clin Invest 126, 3023-3035 (2016).
Blum, A.P., Kammeyer, J.K. & Gianneschi, N.C. Activating Peptides for Cellular Uptake via Polymerization into High Density Brushes. Chem Sci 7, 989-994 (2016).
Banno, A., et al. Downregulation of 26S proteasome catalytic activity promotes epithelial-mesenchymal transition. Oncotarget 7, 21527-21541 (2016).
Aung, A., Theprungsirikul, J., Lim, H.L. & Varghese, S. Chemotaxis-driven assembly of endothelial barrier in a tumor-on-a-chip platform. Lab Chip 16, 1886-1898 (2016).
Aung, A., et al. 3D cardiac mutissues within a microfluidic device with real-time contractile stress readout. Lab Chip 16, 153-162 (2016).
Zhang, Z., et al. Normalization of Naxos plakoglobin levels restores cardiac function in mice. J Clin Invest 125, 1708-1712 (2015).
Xu, D., et al. Heparan Sulfate Modulates Neutrophil and Endothelial Function in Antibacterial Innate Immunity. Infect Immun 83, 3648-3656 (2015).
Weissmiller, A.M., et al. A gamma-secretase inhibitor, but not a gamma-secretase modulator, induced defects in BDNF axonal trafficking and signaling: evidence for a role for APP. PLoS One 10, e0118379 (2015).
Wei, S.C., et al. Matrix stiffness drives epithelial-mesenchymal transition and tumour metastasis through a TWIST1-G3BP2 mechanotransduction pathway. Nat Cell Biol 17, 678-688 (2015).
Shimizu, C., et al. Cardiovascular pathology in 2 young adults with sudden, unexpected death due to coronary aneurysms from Kawasaki disease in childhood. Cardiovasc Pathol 24, 310-316 (2015).
Seidner, G., et al. Identification of Neurons with a Privileged Role in Sleep Homeostasis in Drosophila melanogaster. Curr Biol 25, 2928-2938 (2015).
Schwartz, M., Travesa, A., Martell, S.W. & Forbes, D.J. Analysis of the initiation of nuclear pore assembly by ectopically targeting nucleoporins to chromatin. Nucleus 6, 40-54 (2015).
Roosing, S., et al. Functional genome-wide siRNA screen identifies KIAA0586 as mutated in Joubert syndrome. Elife 4, e06602 (2015).
Rocca, C.J., et al. Treatment of Inherited Eye Defects by Systemic Hematopoietic Stem Cell Transplantation. Invest Ophthalmol Vis Sci 56, 7214-7223 (2015).
Povero, D., et al. Lipid-induced hepatocyte-derived extracellular vesicles regulate hepatic stellate cell via microRNAs targeting PPAR-gamma. Cell Mol Gastroenterol Hepatol 1, 646-663 e644 (2015).
Patra, K.P., et al. Alga-produced malaria transmission-blocking vaccine candidate Pfs25 formulated with a human use-compatible potent adjuvant induces high-affinity antibodies that block Plasmodium falciparum infection of mosquitoes. Infect Immun 83, 1799-1808 (2015).
Numano, F., et al. Galectin-3 is a marker of myocardial and vascular fibrosis in Kawasaki disease patients with giant aneurysms. Int J Cardiol 201, 429-437 (2015).
Naphade, S., et al. Brief reports: Lysosomal cross-correction by hematopoietic stem cell-derived macrophages via tunneling nanotubes. Stem Cells 33, 301-309 (2015).
Morinaga, H., et al. Characterization of distinct subpopulations of hepatic macrophages in HFD/obese mice. Diabetes 64, 1120-1130 (2015).
Midde, K.K., et al. Multimodular biosensors reveal a novel platform for activation of G proteins by growth factor receptors. Proc Natl Acad Sci U S A 112, E937-946 (2015).
Metz, P.J., et al. Regulation of asymmetric division and CD8+ T lymphocyte fate specification by protein kinase Czeta and protein kinase Clambda/iota. J Immunol 194, 2249-2259 (2015).
Matthews, D.W., et al. Feedback in the brainstem: an excitatory disynaptic pathway for control of whisking. J Comp Neurol 523, 921-942 (2015).
Ma, G.S., et al. Therapeutic effects of cell-permeant peptides that activate G proteins downstream of growth factors. Proc Natl Acad Sci U S A 112, E2602-2610 (2015).
Lorenzana, A.O., Lee, J.K., Mui, M., Chang, A. & Zheng, B. A surviving intact branch stabilizes remaining axon architecture after injury as revealed by in vivo imaging in the mouse spinal cord. Neuron 86, 947-954 (2015).
Liu, C., et al. Apoc2 loss-of-function zebrafish mutant as a genetic model of hyperlipidemia. Dis Model Mech 8, 989-998 (2015).
Liao, Z., et al. Interaction of kindlin-2 with integrin beta3 promotes outside-in signaling responses by the alphaVbeta3 vitronectin receptor. Blood 125, 1995-2004 (2015).
Lee, A.M., et al. Role of TGF-beta Signaling in Remodeling of Noncoronary Artery Aneurysms in Kawasaki Disease. Pediatr Dev Pathol 18, 310-317 (2015).
Lao, D.H., et al. Lmo7 is dispensable for skeletal muscle and cardiac function. Am J Physiol Cell Physiol 309, C470-479 (2015).
Lagarrigue, F., et al. A RIAM/lamellipodin-talin-integrin complex forms the tip of sticky fingers that guide cell migration. Nat Commun 6, 8492 (2015).
Jean, S., Cox, S., Nassari, S. & Kiger, A.A. Starvation-induced MTMR13 and RAB21 activity regulates VAMP8 to promote autophagosome-lysosome fusion. EMBO Rep 16, 297-311 (2015).
Israelson, A., et al. Macrophage migration inhibitory factor as a chaperone inhibiting accumulation of misfolded SOD1. Neuron 86, 218-232 (2015).
Holland, A.J., et al. Preventing farnesylation of the dynein adaptor Spindly contributes to the mitotic defects caused by farnesyltransferase inhibitors. Mol Biol Cell 26, 1845-1856 (2015).
Guimaraes-Camboa, N., et al. HIF1alpha Represses Cell Stress Pathways to Allow Proliferation of Hypoxic Fetal Cardiomyocytes. Dev Cell 33, 507-521 (2015).
Geoffroy, C.G., et al. Effects of PTEN and Nogo Codeletion on Corticospinal Axon Sprouting and Regeneration in Mice. J Neurosci 35, 6413-6428 (2015).
Ganguly, A., et al. A dynamic formin-dependent deep F-actin network in axons. J Cell Biol 210, 401-417 (2015).
Font-Burgada, J., et al. Hybrid Periportal Hepatocytes Regenerate the Injured Liver without Giving Rise to Cancer. Cell 162, 766-779 (2015).
Fachinetti, D., et al. DNA Sequence-Specific Binding of CENP-B Enhances the Fidelity of Human Centromere Function. Dev Cell 33, 314-327 (2015).
Embree, M., Liu, J.K., Al-Bassam, M.M. & Zengler, K. Networks of energetic and metabolic interactions define dynamics in microbial communities. Proc Natl Acad Sci U S A 112, 15450-15455 (2015).
Eckharter, C., et al. Schwann Cell Expressed Nogo-B Modulates Axonal Branching of Adult Sensory Neurons Through the Nogo-B Receptor NgBR. Front Cell Neurosci 9, 454 (2015).
de Jong, P.R., et al. TRPM8 on mucosal sensory nerves regulates colitogenic responses by innate immune cells via CGRP. Mucosal Immunol 8, 491-504 (2015).
Davey, S.K., et al. Embedded 3D Photopatterning of Hydrogels with Diverse and Complex Architectures for Tissue Engineering and Disease Models. Tissue Eng Part C Methods 21, 1188-1196 (2015).
Cohen, S.E., Erb, M.L., Pogliano, J. & Golden, S.S. Best practices for fluorescence microscopy of the cyanobacterial circadian clock. Methods Enzymol 551, 211-221 (2015).
Chiang, W.C., et al. Robust Endoplasmic Reticulum-Associated Degradation of Rhodopsin Precedes Retinal Degeneration. Mol Neurobiol 52, 679-695 (2015).
Bossen, C., et al. The chromatin remodeler Brg1 activates enhancer repertoires to establish B cell identity and modulate cell growth. Nat Immunol 16, 775-784 (2015).
Barr, J.J., et al. Subdiffusive motion of bacteriophage in mucosal surfaces increases the frequency of bacterial encounters. Proc Natl Acad Sci U S A 112, 13675-13680 (2015).
Bao, L., Cardiff, R.D., Steinbach, P., Messer, K.S. & Ellies, L.G. Multipotent luminal mammary cancer stem cells model tumor heterogeneity. Breast Cancer Res 17, 137 (2015).
Baek, S.T., et al. An AKT3-FOXG1-reelin network underlies defective migration in human focal malformations of cortical development. Nat Med 21, 1445-1454 (2015).
Aznar, N., et al. Daple is a novel non-receptor GEF required for trimeric G protein activation in Wnt signaling. Elife 4, e07091 (2015).
Alvarez-Mico, X., et al. The Hybrid Pyrroloisoindolone-Dehydropyrrolizine Alkaloid (-)-Chlorizidine A Targets Proteins within the Glycolytic Pathway. Chembiochem 16, 2002-2006 (2015).
Alavi, M.V., et al. In Vivo Visualization of Endoplasmic Reticulum Stress in the Retina Using the ERAI Reporter Mouse. Invest Ophthalmol Vis Sci 56, 6961-6970 (2015).
Agulnick, A.D., et al. Insulin-Producing Endocrine Cells Differentiated In Vitro From Human Embryonic Stem Cells Function in Macroencapsulation Devices In Vivo. Stem Cells Transl Med 4, 1214-1222 (2015).
Zhao, J.J., et al. Induction of retinal progenitors and neurons from mammalian Muller glia under defined conditions. J Biol Chem 289, 11945-11951 (2014).
Xue, M., Atallah, B.V. & Scanziani, M. Equalizing excitation-inhibition ratios across visual cortical neurons. Nature 511, 596-600 (2014).
Wu, M., Robinson, J.E. & Joiner, W.J. SLEEPLESS is a bifunctional regulator of excitability and cholinergic synaptic transmission. Curr Biol 24, 621-629 (2014).
Vitre, B., et al. Kinetochore-microtubule attachment throughout mitosis potentiated by the elongated stalk of the kinetochore kinesin CENP-E. Mol Biol Cell 25, 2272-2281 (2014).
Torres-Gonzalez, M., Gawlowski, T., Kocalis, H., Scott, B.T. & Dillmann, W.H. Mitochondrial 8-oxoguanine glycosylase decreases mitochondrial fragmentation and improves mitochondrial function in H9C2 cells under oxidative stress conditions. Am J Physiol Cell Physiol 306, C221-229 (2014).
Teodorof, C., et al. Intracellular mannose binding lectin mediates subcellular trafficking of HIV-1 gp120 in neurons. Neurobiol Dis 69, 54-64 (2014).
Skowronska-Krawczyk, D., et al. Required enhancer-matrin-3 network interactions for a homeodomain transcription program. Nature 514, 257-261 (2014).
Shang, X., Lin, X. & Howell, S.B. Claudin-4 controls the receptor tyrosine kinase EphA2 pro-oncogenic switch through beta-catenin. Cell Commun Signal 12, 59 (2014).
Shabel, S.J., Proulx, C.D., Piriz, J. & Malinow, R. Mood regulation. GABA/glutamate co-release controls habenula output and is modified by antidepressant treatment. Science 345, 1494-1498 (2014).
Schutt, C.E., Ibsen, S.D., Benchimol, M.J., Hsu, M.J. & Esener, S.C. Manipulating nanoscale features on the surface of dye-loaded microbubbles to increase their ultrasound-modulated fluorescence output. Small 10, 3316-3324 (2014).
Schaffer, A.E., et al. CLP1 founder mutation links tRNA splicing and maturation to cerebellar development and neurodegeneration. Cell 157, 651-663 (2014).
Rush, A.M., et al. Intracellular mRNA regulation with self-assembled locked nucleic acid polymer nanoparticles. J Am Chem Soc 136, 7615-7618 (2014).
Povero, D., et al. Circulating extracellular vesicles with specific proteome and liver microRNAs are potential biomarkers for liver injury in experimental fatty liver disease. PLoS One 9, e113651 (2014).
Oakes, J.M., Breen, E.C., Scadeng, M., Tchantchou, G.S. & Darquenne, C. MRI-based measurements of aerosol deposition in the lung of healthy and elastase-treated rats. J Appl Physiol (1985) 116, 1561-1568 (2014).
Novarino, G., et al. Exome sequencing links corticospinal motor neuron disease to common neurodegenerative disorders. Science 343, 506-511 (2014).
Niv, Y., et al. Membrane-bound mucins and mucin terminal glycans expression in idiopathic or Helicobacter pylori, NSAID associated peptic ulcers. World J Gastroenterol 20, 14913-14920 (2014).
Mueller, J.L., McGeough, M.D., Pena, C.A. & Sivagnanam, M. Functional consequences of EpCam mutation in mice and men. Am J Physiol Gastrointest Liver Physiol 306, G278-288 (2014).
Moore-Morris, T., et al. Resident fibroblast lineages mediate pressure overload-induced cardiac fibrosis. J Clin Invest 124, 2921-2934 (2014).
Meves, J.M. & Zheng, B. Extrinsic inhibitors in axon sprouting and functional recovery after spinal cord injury. Neural Regen Res 9, 460-461 (2014).
Lyon, R.C., et al. Connexin defects underlie arrhythmogenic right ventricular cardiomyopathy in a novel mouse model. Hum Mol Genet 23, 1134-1150 (2014).
Lun, A.S., Chen, J. & Lange, S. Probing muscle ankyrin-repeat protein (MARP) structure and function. Anat Rec (Hoboken) 297, 1615-1629 (2014).
Lin, X., Shang, X., Manorek, G., Fofana, M. & Stephen, B.H. Integrin alphaV modulates the cellular pharmacology of copper and cisplatin by regulating expression of the influx transporter CTR1. Oncoscience 1, 185-195 (2014).
Lazic, M., et al. Reduced dietary omega-6 to omega-3 fatty acid ratio and 12/15-lipoxygenase deficiency are protective against chronic high fat diet-induced steatohepatitis. PLoS One 9, e107658 (2014).
Lazic, M., et al. Differential regulation of inflammation and apoptosis in Fas-resistant hepatocyte-specific Bid-deficient mice. J Hepatol 61, 107-115 (2014).
Law, R., et al. Biallelic truncating mutations in FMN2, encoding the actin-regulatory protein Formin 2, cause nonsyndromic autosomal-recessive intellectual disability. Am J Hum Genet 95, 721-728 (2014).
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