Research Studies: Corticobasal Degeneration & Progressive Supranuclear Palsy

Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL,  Enrolling)

This research study is looking to learn more about cognition and/or movement problems in patients with frontotemporal dementia.

Patients who qualify are those who have been diagnosed with the following or have a blood relative who is diagnosed with the following:

  • Sematic variant Primary Progressive Aphasia (PPA)
  • Progressive Supranuclear Palsy (PSP)
  • Frontotemporal Dementia with Amyotrophic Lateral Sclerosis (FTD-ALS)
Participation includes an evaluation of cognition, a physical examination, questionnaires, and a sample of blood. Patients may also be asked for an MRI scan or cerebrospinal fluid. If FTLD runs in the patient's family, they may be asked to return in one year for a follow-up appointment where assessments will be repeated. For more research study information, please contact our study coordinators at mdcresearch@ucsd.edu

For more information on all participating sites, please follow this link: https://www.rarediseasesnetwork.org/ARTFL/index.htm

 

Atypical Parkinsonism: Corticobasal Degeneration

Four Repeat Tauopathy Neuroimaging Initiative (4RTNI-2) (active)

This study is evaluating the best method of analysis to track patients with Progressive Supranuclear Palsy (PSP) and Corticobasal Degeneration (CBD) over time. During this 2 year-long study, patients will be asked to come in for 3 study visits (at baseline, 6 month, 12 months, and 24 months) to complete a neurological examination, study partner questionnaires, memory testing, lumbar puncture, biospecimen collection, MRI, and a PET scan. Patients with PSP or CBD between the ages of 45 - 90 with a reliable study partner are eligible. For more information on this study, please contact study coordinators at mdcresearch@ucsd.edu
For more information on all participating sites, please follow this link: https://www.rarediseasesnetwork.org/ARTFL/index.htm