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Research Focus Areas

Listed alphabetically by subject area. Please send updates to

4D Nucleome Research

4D Nucleome Research Center and Organizational Hub at UC San Diego: Principal Investigator Shu Chien, MD, PhD


Molecular mechanisms of aging; impact of inflammation on the brain; chronic diseases of aging.

Allergy and Immunology

Molecular and cell biology of allergy; immune-mediated and inflammatory diseases; mucosal immunity.


Arthritis and Inflammatory Disease

Pathogenesis and treatment.


Atherosclerotic Heart Disease


Biomedical Informatics

Bioinformatics; clinical informatics; global health informatics and telemedicine; infrastructure, privacy technology and health information exchange.

Core bioinformatics expertise to manage and analyze large molecular datasets, especially from next-generation sequencing. Special emphasis in genomics, systems biology and personalized medicine.

Bone Marrow Transplantation

See Hematology-Oncology


See Hematology-Oncology


Atherosclerosis; cardiac electrophysiology; cardiac mechanics; heart failure; integrins in inflammation; interventional cardiology; molecular cardiology; physiology and pharmacology.

Clinical Decision Support

Biomedical Informatics, an academic division in the UC San Diego School of Medicine and a department of UC San Diego Health.

Clinical Trials



Etiology, treatment, and prevention; molecular mechanisms; pathogenesis of diabetic kidney disease; the contribution of the kidney to cardiovascular disease in diabetes and obesity.

Digestive Diseases

Celiac disease; gastrointestinal infection; intestinal inflammatory disease.

Endocrinology and Metabolism

Obesity; lipid research; pituitary; thyroid; signal transduction; transcription; calcium and bone; reproductive endocrine diseases.


Division of Gastroenterology


Division of Gastroenterology

Genomic Medicine


Molecular mechanisms of aging; impact of inflammation on the brain.

Global Public Health

HIV/AIDS, malaria, tuberculosis; risk factors, transmission, treatment, prevention, border health, health care utilization, STDs, viral hepatitis, substance use, migration and health, and social justice.


Heart Failure

Division of Cardiovascular Medicine


Experimental therapeutics; hematological malignancies; chronic lymphocytic leukemia; stem cell biology; tumor biology/immunology; hematopoiesis; platelet-vascular biology.


See Liver Disease



Pathogenesis, prevention, risk factors, transmission, treatment.


Research and training in hospice and palliative care - Divisions of Hematology-Oncology and Bone Marrow Transplantation

Hospital Medicine

Glycemic control, venous thromboembolism prevention, transitions of care.


Infectious Diseases

HIV and opportunistic infections; drug resistance; hepatitis B and C; Leptospira; malaria; tuberculosis; microbial pathogenesis; international medicine; neurovirology; prevention; tropical medicine; parasitology.


Inflammatory Bowel Disease

Developing new biotechnology therapies; conducting multicenter clinical trials; clinical pharmacology of medications used in treatment.

See Also Digestive Diseases

Kidney Disease / Kidney Injury

Development; physiology and pathophysiology; hypertension; immuno-pathogenesis and transplantation; function in early diabetes and diabetic nephropathy; acute injury and outcomes research; failure.

Leukemia, Myeloproliferative Disorders

Cancer clinical trials, cellular-immunotherapy, diagnostics, experimental therapeutics, gene immunotherapy, regenerative medicine, stem cell medicine, tumor biology.

Lipid Research

Liver Disease

Epidemiology and biomarkers for liver disease; multi-targeted therapies for liver cancer; molecular pathogenesis of fibrotic liver disease and the genetic basis of liver disorders;
progression of chronic liver diseases; hepatic fibrosis; alcoholic liver disease; liver failure; hepatitis B and C; clinical trials; treatments; transplantation; population screening; vaccination.

Medical Genetics

Genomics and personalized medicine; systems biology.

Division of Medical Genetics ​​


Network Approaches to Identify Cancer Drivers from High-Dimensional Tumor Data (NIH Early Independence Award to Hannah Carter, PhD)

Training Program in Basic and Clinical Genetics (NIH Training Grant)

Nonalcoholic Fatty Liver Disease (NAFLD)


Palliative Medicine

Pancreatic Cancer

Pulmonary and Critical Care Medicine

COPD; drug-resistant tuberculosis; pulmonary function during weightlessness; respiratory biology; sleep medicine.

See Also Division of Physiology

Quality Improvement

Division of Hospital Medicine

Regenerative Medicine

Rheumatic Diseases

Biology of immunologic and inflammatory diseases; pathogenesis and treatment of rheumatoid arthritis.

Sleep Medicine

The pathogenesis of sleep apnea; metabolic/cardiovascular complications of sleep disorders; mechanical ventilation in acute respiratory distress syndrome.

Division of Pulmonary, Critical Care & Sleep Medicine

Smoking and Health

Systems Biology

Division of Biomedical Informatics
Division of Medical Genetics

Tropical Medicine

Brucellosis, Leptospira, malaria, Plasmodium vivax.


Vascular Diseases and Thrombosis

Deep vein thrombosis; chronic thrombotic venous disease.

DVT prevention in inpatients: