Dr. Trey Ideker

​​​​​​Dr. Trey IdekerDr. Ideker is a Professor of Medicine at UC San Diego. He is the Director of the National Resource for Network Biology, the San Diego Center for Systems Biology,  and the Cancer Cell Map Initiative. He is a pioneer in using genome-scale measurements to construct network models of cellular processes and disease.

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 National Resource for Network BiologySan Diego Center for Systems Biology


About the Ideker Lab

Our goal at the Ideker Lab is to develop a new type of medicine based on knowledge of the complete physical and functional wiring of the cell. ​We are developing new ways of mapping these wiring diagrams directly from genome-scale measurements (genomic, proteomic, and metabolomic) and for using these maps to translate the increasingly complex data gathered from patients to predict disease outcomes and develop better treatments.

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Featured News & Research

Combinatorial CRISPR-Cas9 screens for de novo mapping of genetic interactions. JP Shen, et. al., NatMethods  (2017). [PDF] [PubMed]  Press: GEN News HighlightsSD Union TribuneUCSD Health News, BioTechniques.

Interaction Landscape of Inherited Polymorphisms with Somatic Events in Cancer. Hannah Carter, et. al., Cancer Discovery (2017). [PDF] [PubMed]

Active Interaction Mapping Reveals the Hierarchical Organization of Autophagy
Michael Kramer, et. al., MolCell (2017). [PDF] [PubMed]

The Real Value of an Atlas, Trey Ideker. NIH Biomedical Informatics Blog (2016). [PDF]

Cancer Bioinformatics: A Disease of the Genome, Liz Harley. Frontline Genomics Magazine (2016). [PDF]

Methylome-wide Analysis of Chronic HIV Infection Reveals Five-Year Increase in Biological Age and Epigenetic Targeting of HLA. Andy Gross, et. al., MOLCELL (2016). [PDF] [GitHub] Press: NPRNIHUCSD HealthMolCell Interview

Translation of Genotype to Phenotype by a Hierarchy of Cell Subsystems*. Mike Yu, et. al., Cell Systems (2016). [PDF] [*Cover Art] [Press]