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Dr. John Chang studies the cellular and molecular mechanisms underlying T lymphocyte fate specification. Dr. Chang is the recipient of several awards, including the HHMI Physician-Scientist Early Career Award and the NIH Director's New Innovator Award, and is currently funded by grants from the National Institutes of Health and the Kenneth Rainin Foundation. Dr. Chang is a member of the American Society for Clinical Investigation and has received multiple awards, including the AGA-GRG Young Investigator Award in Basic Science.
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A central problem faced by multi-cellular organisms is the need for rare progenitor cells to continually produce terminally differentiated cells while also preserving a self-renewing lineage. In the mammalian immune system, T lymphocytes face a similar need for simultaneous differentiation and regeneration. The goal of our research is to understand the molecular mechanisms enabling activated T lymphocytes to give rise to differentially fated progeny.
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Lab Location University of California, San Diego Biomedical Research Facility 2 (BRF2) Room 5220L
Mailing Address University of California, San Diego 9500 Gilman Drive #0063 La Jolla, CA 92093-0063
Phone: 858-822-7568 Fax: 858-822-7652
Congrats to Nadia Kurd, Arthur He, and the @Goldrathlab and @yeo_lab for their work on this new study! https://t.co/Eloezvv24d— John Chang (@UCSDChangLab) May 20, 2020
Congrats to Nadia Kurd, Arthur He, and the @Goldrathlab and @yeo_lab for their work on this new study! https://t.co/Eloezvv24d
Kuddos to Kyla Omilusik and Justin Milner and the Goldrath and Chang labs for their study out today in Immunity: Heterogenous populations of tissue-resident CD8+ T cells are generated in response to infection and malignancy. https://t.co/gUHh35Lc1z, Well done!— Goldrath Lab (@GoldrathLab) May 19, 2020
Kuddos to Kyla Omilusik and Justin Milner and the Goldrath and Chang labs for their study out today in Immunity: Heterogenous populations of tissue-resident CD8+ T cells are generated in response to infection and malignancy. https://t.co/gUHh35Lc1z, Well done!