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Sleep in HIV

Thankfully, major strides have been made in the treatment of Human Immunodeficiency Virus (HIV) leading to greatly prolonged life expectancy for people on anti-retroviral therapy (ART). However, fatigue and early cardiovascular disease are major problems. Might sleep apnea be a culprit? Here's what we know about OSA in HIV: 

1. OSA is appears to be common in those with HIV. 

 2. Traditional OSA risk factors may not predict OSA in PLWH. 

3. Untreated OSA may be relevant for symptoms in PLWH. 

4. Untreated OSA is likely to be associated with ongoing inflammation. 

5. Few PLWH with OSA are diagnosed or treated. 

We are conducting experiments to determine: - If people with HIV are predisposed to OSA - What the impact of sleep and sleep apnea are on fatigue and quality of life in people with HIV.


Chuck Hicks MD 

Maile Karris MD 

Igor Grant MD 

Sonia Ancoli Israel PhD 

Atul Malhotra MD 

Jeremy Orr MD 

Dae Kang PhD 

Interested in Participating? If you are in the San Diego area and would like to be considered, please call 858-246-2154 or email These studies are NIH funded and registered on (NCT03064204, NCT03575143)