Melatonin and Obstructive Sleep Apnea

‚ÄčOur research team at UC San Diego is conducting a study to learn more about the effects of Melatonin treatment in patients with obstructive sleep apnea (OSA). We are seeking volunteers who have been diagnosed with OSA but are not currently using treatment for it. The results of this study may improve our understanding of OSA and help in the development of new and improved treatments. 

Principal and Co-Investigators:

Atul Malhotra, MD and Naomi Deacon, PhD

Maximum compensation for completing entire study (24-28 hours total over 2 weeks, most spent sleeping):



  • Age 18-70 years
  • Known diagnosis of OSA but not currently using CPAP or any other treatment for OSA
  • Non-smoker
  • What you may be asked to do during this study:

  • Two overnight sleep studies at our UCSD Hillcrest sleep laboratory, performed before and after one week of Melatonin use
  • Wear a wristband which records movement to determine home sleep patterns
  • Take Melatonin or placebo pills
  • Complete study questionnaires    
  • Two or more blood draws
  • Breathing tests using both high carbon dioxide and low oxygen 
  • If you have questions about this study, please contact us at, or (858)246-2154. 

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