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William Go, MD, PhD

William Go

Dr. Go graduated magna cum laude and received his Phi Beta Kappa, Sigma Xi from Carleton College in 1998. He then entered the Medical Scientist Training Program at UC San Diego and received his PhD in biomedical sciences with a focus in immunology in 2004 and his MD in 2006. He has been awarded grants from the Stein Institute for Research on Aging and the Glenn/American Federation for Aging Research. Dr. Go's research has been the study of transcriptional regulation of T cells in both in vitro and in vivo models. He is currently a first year resident and he will pursue his fellowship training in hematology-oncology.

Selected Publications

Li, S.Z., McDill, B.W., Kovach, P.A., Ding, L., Go, W.Y., Ho, S.N. Chen, F. Calcineurin/NFATc and TonEBP/NFAT5 regulate AQP2 expression in response to osmotic change. Manuscript in preparation to be submitted 2006.

Park, S.H., Kim, D.J., Jeon, U.S., Go, W.Y., Ho, S.N., Woo, S.K. and Kwon, H.M. 2004. Urinary concentration defect in TonEBP +/- mice. American Society of Nephrology Meeting.

Go, W.Y., Liu, X., Roti, M.A., Liu, F., and Ho, S.N. 2004. NFAT5/TonEBP mutant mice define osmotic stress as a critical feature of the lymphoid microenvironment. Proceedings of the National Academy of Science. 101(29):10673-8.

Lu, Q., Liu, X., Trama, J., Roti, M. A., Go, W.Y., and Ho, S.N. 2004. Identification of the cytoskeletal regulatory protein a-adducin as a target of T cell receptor signaling. Molecular Immunology. 41(4): 435-447.

Trama, J., Go, W.Y., Ho S.N. 2002. The osmoprotective function of the NFAT5 transcription factor in T cell development and activation. Journal of Immunology. 169(10):5477-5488.

Go, W.Y., Ho S.N. 2002. Optimization and direct comparison of the dimerizer and reverse tet transcriptional control systems. Journal of Gene Medicine. 4(3):258-270.

Takeda, T., Go, W.Y., Orlando, R.A., Farquhar, M.G. 2000. Expression of podocalyxin inhibits cell-cell adhesion and modifies properties in Madin-Darby Canine Kidney Cells. Molecular Biology of the Cell. 11(9): 3219-3232.

Go, W.Y., Holicky, E.L., Hadac, E.M., Rao, R.V., Miller, L.J. 1998. Identification of a domain in the carboxy terminus of CCK receptor that affects its intracellular trafficking. American Journal of Physiology. 275(1 Pt 1):G56-62.

Go, W.Y., Roettger, B.F., Holicky, E.L., Hadac, E.M., Miller, L.J. 1997. Quantitative dynamic multicompartmental analysis of cholecystokinin receptor movement in a living cell using dual fluorophores and reconstruction of confocal images. Analytical Biochemistry. 247(2):210-215.