The Guma lab studies metabolic changes in cells critical for rheumatoid arthritis and psoriatic arthritis pathogenesis, specially fibroblast-like synovioctyes and macrophages to offer a novel and additional approach for combination therapy independent of systemic immunosuppression. We also conduct clinical and translational investigations to identify noninvasive circulating metabolic biomarkers to identify patients at high risk for joint damage.
We also are interested in gaining a better understanding of relapsing polychondritis, a rare condition characterized by recurrent inflammation of cartilage, not only in joints but also in other tissues throughout the body.
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