About the Lab
Dr. Cantor’s pioneering studies on CD98 in adaptive immunity have shed light on the connection between adhesive signaling and nutrient transport in lymphocyte clonal expansion. CD98 and other integrin-associated proteins govern the expansion and migration of T and B cells in ways that strongly regulate protective immunity, autoimmunity, and anti-tumor immunity. The Cantor lab is currently investigating how CD98 is regulated, how CD98 controls lymphocyte proliferation, and how this protein could be exploited to boost weak protective immunity or prevent/treat autoimmunity. His research has also expanded to study how modulating integrin-associated proteins could improve adoptive immunotherapy for cancer.