About the Lab

Dr. Broderick earned her undergraduate degree from Syracuse University in New York. She received her doctorate in tumor immunology and her medical degree at the University of Buffalo in New York. She completed her Pediatric residency and Allergy/Immunology fellowship at UC San Diego, where she developed an interest in patients with primary immunodeficiencies and autoinflammatory syndromes. She is the Director of the Recurrent Fever Disorders Clinic at Rady Children’s Hospital of San Diego.

Dr. Broderick is an active member of the American Academy of Allergy, Asthma, and Immunology; the International Society of Systemic Auto-Inflammatory Diseases; the Clinical Immunology Society and the San Diego Allergy Society.

Dr. Broderick is the recipient of a number of distinctions and research awards from organizations including the American Academy of Pediatrics, the Thrasher Research Fund, The Hartwell Foundation, the A.P. Giannini Foundation and the Arthritis National Research Foundation. Most recently, she was honored with the American Academy of Allergy, Asthma and Immunology Faculty Development Award.

Laboratory Personnel
Contact information and photos of our scientists, research associates, and laboratory administrators are provided on the People page. See Contact Us for mailing addresses and telephone numbers for the laboratory.

Funding & Research Studies
Current active major grants funding the Broderick laboratory investigations include the following:
A research program project funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) on the genetics of PFAPA syndrome.
A faculty development grant from the AAAAI Foundation to study molecular mechanisms of immunodysregulatory disorders.

Dr. Broderick has several active collaborations both within and outside of the Division.
She is a co-investigator with Division colleague Dr. Hal M. Hoffman to study the role of NLRP3 in autoinflammatory disease. Their recent review was published in JACI: Hoffman HM, Broderick L. The role of the inflammasome in patients with autoinflammatory diseases.
She works closely with Dr. Ariel Feldstein (Division of Gastroenterology, Department of Pediatrics) to investigate the role of the NLRP3 inflammasome in liver inflammation and fibrosis, most recently published in the Journal of Clinical Investigation: McGeough MD, Wree A, Inzaugarat M, Haimovich A, Johnson CD, Pena CA, Goldbach-Mansky R, Broderick L, Feldstein AE, Hoffman HM. 
TNF regulates transcription of NLRP3 inflammasome components and inflammatory molecules in cryopyrinopathies.

Mentoring

BILD99/BISP196/BISP199
We welcome students to participate in the Biomedical Sciences Independent Research Program (BILD99/BISP196/BISP199). Please inquire by email to lbroderick@ucsd.edu for projects. 

Combined BS/MS in Biology

After successful completion of BISP199, students are welcome to discuss continuing with a Master’s degree project.

Postdoctoral Fellows
Interested candidates should inquire by email to lbroderick@ucsd.edu. Please attach your curriculum vitae, a PDF of any recent publication(s) and the names and email addresses of three professional references.