About the Aceves Lab

Seema S. Aceves, MD, PhD

Seema Aceves, MD, PhDSeema Sharma Aceves, MD, PhD, performed her undergraduate studies at Claremont McKenna College, where she graduated magna cum laude and Phi Beta Kappa. She completed her MD and PhD as part of the NIH-funded Medical Scientist Training Program at UC San Diego after doing research with Nobel Laureate Edward B. Lewis at the California Institute of Technology.

She completed her pediatrics residency and allergy, immunology fellowship at UC San Diego. During her fellowship, she was awarded an American Lung Association Fellowship grant as well as a GlaxoSmithKline Respiratory Institute Fellowship award.

In 2002, Dr. Aceves joined the faculty at UC San Diego and Rady Children’s Hospital, San Diego/Children’s Specialists of San Diego, where she is currently an associate professor of pediatrics and medicine at the Division of Rheumatology, Allergy and Immunology. She directs the Eosinophilic Gastrointestinal Disorders clinic at Rady Children’s Hospital, San Diego, where more than 500 children with eosinophilic gastrointestinal diseases are cared for each year.

Dr. Aceves was named a Physician of Exceptional Excellence in the 2012 and 2013 "San Diego's Top Doctors" survey from the San Diego County Medical Society and San Diego Magazine. She was also listed as one of the nation's top doctors on the 2012-2013 U.S.News & World Report "Top Doctors" List.

Her laboratory research on eosinophilic esophagitis (EoE) takes place at the School of Medicine at UCSD. Dr. Aceves is the author of numerous publications in EoE. Her laboratory was the first to begin dissecting the mechanisms of tissue remodeling that leads to disease complications such as strictures and food impactions. 

Dr. Aceves is also a co-inventor of oral viscous budesonide, a novel topical esophageal steroid formulation. She serves as the principal investigator on a number of multi- and single center EoE trials.

She has served on numerous non-federal peer review bodies and is a current member of the Cellular Integrative Molecular Gastroenterology study section of the National Institutes of Health. She has served as a reviewer for a number of gastroenterology and allergy/immunology journals and is a member of the editorial board for the Journal of Allergy and Clinical Immunology.

Dr. Aceves is the recipient of a number of distinctions including junior faculty awards from the American Academy of Allergy, Asthma, and Immunology (AAAAI); the American College of Allergy, Asthma, and Immunology; and the American Partnership for Eosinophilic Disorders (APFED).

She is a member of the Executive Council and the Scientific Research Chair for The International Gastrointestinal Researchers (TIGERS), a member of the Medical Advisory Panel for APFED and the vice chair of the Eosinophilic Gastrointestinal Disorders Committee for the AAAAI.

More About Dr. Aceves

In 2010, Dr. Aceves and coworkers published the Journal of Allergy and Clinical Immunology article, Mast cells infiltrate the esophageal smooth muscle in patients with eosinophilic esophagitis, express TGF-β1, and increase esophageal smooth muscle contraction.  Abstract of the article

Laboratory Personnel

Contact information for our research associates and students is provided on the People page. See Contact Us for mailing addresses and telephone numbers for the laboratory.


Research Studies

Current active major grants funding the Aceves laboratory investigations include the following.


Clinical and Research Links

Rady Children's Hospital - San Diego