Fourth Year Fellows

  • 2006: University of Utah, B.S. Biology
  • 2013: University of California, Los Angeles, M.A. Education
  • 2014: University of California, San Diego, M.D.
  • 2018: Los Angeles County + University of Southern California, Internal Medicine-Pediatrics Residency
  • 2019: Los Angeles County + University of Southern California, Internal Medicine-Pediatrics Chief Resident
  • Patient-physician interactions
  • Diverse learning environments in medical education
  • Physician workforce trends
  • Health disparities
  • Transitions of care
  1. Powell, T., Arias Garcia, K., Lopez, A., Bailey, J., Willies-Jacobo, L.: Program in Medical Education-Health Equity (PRIME-HEq): Training Future Physicians to Care for Underserved Communities. Journal of Health Care for the Poor and Underserved, 27(3):937-46, 2016.

Dr. Barnes was born in Leeds, UK and moved to Minnesota to complete High School. She then went to Johns Hopkins, where she wrote her French thesis on TB in 19th Century French Literature and did research on exercise in Cystic Fibrosis. She then returned to the cold at the University of Minnesota for Medical School, where she continued to work in Cystic Fibrosis this time focusing on Pseudomonas transmission. During this she spent a year in Uganda studying malaria. She then followed the sun to Residency at UC San Diego where she did research on post-arrest outcomes. Due to the wonderful people, she stayed for a year as an Hospitalist and then for Fellowship. She is currently studying the effect of hypoxia in a COVID mouse model. She enjoys solo travel, hiking, poor piano-playing and trying to keep plants alive.
  • 2005-2009: Johns Hopkins University, BA French
  • 2010-2015: University of Minnesota Medical School, MD
  • 2015-2018: UC San Diego, Internship & Residency, Internal Medicine
  • 2018-2019: UC San Diego, Hospitalist
  • 2019-2022: UC San Diego, Pulmonary & Critical Care Medicine Fellowship
  • Cystic Fibrosis, Bronchiectasis
  • Critical Care
  • International Medicine
  • COVID acute lung injury
  • Barnes LA, Gaillard PR, Menk JS, Regelmann WA. Pseudomonas aeruginosa Prevalence Decreased in Children after Separation of Pediatric from Adult Cystic Fibrosis Clinics. Submitted. Pediatric Pulmonology. 2018 Dec;53(12):1604-1610. PMID:30353693
  • Paranjape SM, Barnes LA, Carson KA, von Berg K, Loosen H, Mogayzel PJ Jr. Exercise improves lung function and habitual activity in children with cystic fibrosis. J Cyst Fibros. 2012 Jan;11(1):18-23. PMID: 2189043

Sean DeWolf

Dr. DeWolf was born and raised in Oakland, CA. After high school, he left the California sunshine for the east coast, where he attended Villanova University. He spent the latter two years of his undergraduate education studying B cell development in a basic science lab, which ultimately proved to be the beginning of a great passion for bench research and immunology. After graduation he spent a year in southern Mexico before returning to California for his medical school at UCSD. He began working in a lab that studied how innate immunity initiated and propagated acute kidney injury and thought he would end up as a transplant nephrologist. During his 4th year of medical school, however, he rotated through the ICU and fell in love with critical care medicine. He stayed at UCSD for his residency and continued to work in the research area that he now intends to make his career. He enjoys playing golf and basketball and taking his dog on walks with his wife.   
  • 2007-2011: Bachelor of Sciences; Villanova University
  • 2012-2016: M.D. University of California San Diego, School of Medicine
  • 2016-2019: Residency, University of California San Diego
  • Innate immunity in acute lung injury and acute kidney injury
  • Lung-kidney interaction during critical illness 
  • Cell signaling and molecular biology 
  • DeWolf, SE, Shigeoka AA, Scheinok A, Kasimsetty SG, Welch AK, McKay BD. Expression of TLR2, NOD1, and NOD2 and the NLRP3 inflammasome in Renal Tubular Epithelial Cells of Male versus Female mice. Nephron. 2017; 137 (1): 68-76
  • Kasimsetty SG, DeWolf SE, Shigeoka AA, McKay DB. Regulation of TLR2 and NLRP3 in Primary Murine Renal Tubular Epithelial Cells. Nephron Clin Pract 2014; 127: 119-123.
  • Jones MA, DeWolf SE, Vacharathit V, Yim M, Spencer S, Bamezai AK. Investigating B cell development, natural and primary antibody responses in Ly-6A/Sca-1deficient mice. PLOS ONE. 2016; 11 (6)

Cameron McGuire

Dr. McGuire was born in Chicago, but raised in Baltimore, MD. In college he became fascinated by the history of science and medicine and wrote his history thesis on the sociology of Charles Darwin’s concept of natural selection. Since college he has followed a circuitous path with stops at: the NIH doing research on cardiac myocyte survival and vascular smooth muscle cell migration, the University of Chicago doing research on DNA repair following exposure to ionizing radiation or cisplatinum, Tulane University doing research on the role of endothelin signaling in intrarenal renin production, and University of Colorado doing research on heart failure medication adherence and nonpharmacologic interventions for the acute respiratory distress syndrome. Ultimately, he hopes to pursue a research career in pulmonary physiology, pulmonary vascular medicine, and their overlap in the ICU. His interests include: cooking, travel, jazz, history, classic movies, and cocktails to name a few.
  • 2003-2007: Trinity College (Hartford, CT) BS - Biology; BA - History
  • 2009-2010: Loyola University Chicago MA - Medical Sciences
  • 2011-2015: Tulane School of Public Health and Tropical Medicine MPH - Epidemiology
  • 2011-2015: Tulane University School of Medicine: MD
  • 2015-2018: University of Colorado School of Medicine Internal Medicine Resident
  • 2018-2019: University of Colorado School of Medicine Chief Resident
  • Matlock DD, McGuire WC, Magid M, Allen LA. Decision making in advanced heart failure: bench, bedside, practice, and policy. Heart Failure Reviews 22(5): 559-564, September 2017.  
  • McGuire C, Liu L, Prieto M. The role of endothelin-1 in collecting duct renin synthesis and secretion. Journal of Investigative Medicine 61(2): 449, February 2013. (Abstract)  
  • Budke B, Logan HL, Kalin JH, Zelivianskaia AS, Cameron McGuire W, Miller LL, Stark JM, Kozikowski AP, Bishop DK, Connell PP. RI-1: A chemical inhibitor of RAD51 that disrupts homologous recombination in human cells. Nucleic Acids Research 40(15): 7347-57, August 1, 2012. 
  • Renn CL, Lessans S, McGuire WC, Smith B, Traub RJ, Dorsey SG. Brain-derived neurotrophic factor modulates antiretroviral-induced mechanical allodynia in the mouse. Journal of Neuroscience Research 89(10): 1551-65, June 6, 2011.

Dr. Pearce grew up in Denver, Colorado. She completed her undergraduate degree in English at Colgate University in New York. She then went to medical school in New Orleans at Tulane University school of Medicine. In medical school she was inducted into the Alpha Omega Alpha Honor Society and received Merck Manual Award for Academic Excellence as well as the American Medical Women’s Association Glasgow-Rubin Achievement Award. She moved to the west coast for residency and completed her internship and residency in internal medicine at UC San Diego. During residency she focused her research on cardiac arrest outcomes and prognostic indicators. In fellowship, her research interests have shifted to mechanical ventilation, lung protective ventilation, and use of new techniques/technology to assess ventilation distribution. Her interests outside of the hospital include hiking, yoga, skiing, and travel.
  • 2006-2010 Colgate University, B.A. English, Hamilton, NY
  • 2012-2016 Tulane University School of Medicine, MD, New Orleans, LA
  • 2016-2019 UC San Diego, Internship and Residency, Internal Medicine, San Diego, CA
  • Acute lung injury and mechanical ventilation
  • Critical Care Outcomes
  • Electrical impedance tomography
  • Pearce AK, Davis DP, Minokadeh A, Sell RE. Initial End-tidal carbon dioxide as a prognostic indicator for inpatient PEA arrest. Resuscitation 2015; 92:77-81.
  • Farasat S, Dorsch JJ, Pearce AK, , Moore AA, Martin JL, Malhotra A, Kamdar BB. Sleep and Delirium in Older Adults. Curr Sleep Med Rep. 2020 Jul 27:1-13
  • Pearce A. ,, Sell R.E. (2020) Prone Ventilatory Therapy in Critically Ill Cancer Patients. In: Nates J., Price K. (eds) Oncologic Critical Care. Springer, Cham.

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