Resources and Previous Event Information

Resources for Grant Proposals Related to CPGLO

Suggested Grant Proposal Text

The UC San Diego Center for Physiological Genomics of Low Oxygen (CPGLO) is a multidisciplinary team that supports collaborative research on the biology of hypoxia in natural populations and model systems. The goal is to explain individual differences in responses to hypoxia that are observed in patients with heart and lung disease, as well as in human and animal populations living at high altitude. CPGLO provides resources for this such as The Genetics of Altitude Adaptation Consortium (TGAAC), which collates genomic data from high-altitude human populations collected by different research groups for analysis on a common platform. CPGLO is co-directed by faculty from the UCSD School of Medicine (Simonson, Malhotra, Powell), Scripps Institution of Oceanography (Ponganis) and UCSD Dept. of Anthropology (Non) to promote interdisciplinary collaborations and innovative large-scale research projects. CPGLO sponsors in-person and virtual meetings to plan grant proposals plus an annual summit with international leaders in the field to identify new research opportunities and priorities.

Previous Summit Information

CPGLO Summit 2017

Breakout Sessions


Two simultaneous breakout sessions are scheduled from 1:30-2:30pm (Session 1 and Session 2) and two more from 2:45-3:45pm (Session 3 and Session 4) Tuesday afternoon in the second-floor conference rooms in MET

Each session will be facilitated by CPGLO members.  These "think-tank" sessions will be structured around specific themes* relevant to CPGLO grant proposals.  We encourage Participants to bring relevant proposal ideas to any of the sessions.  Please email for more information.

Registered Participants may refer to the back of their nametag for their scheduled Sessions provided at check in.  PLEASE BE SURE TO ATTEND YOUR REGISTERED SESSION. 

In the final 15 minutes of each Session, Participants will help create a summary that will be presented by one or two members of their group in the MET Lower Auditorium at 4:00pm.  Prizes will be awarded based on the most innovative, interdisciplinary, fundable ideas.

*The Breakout Session themes are based on time domains of adaptation.

1:30 - 2:30 PM

Session 1: MET 211 

Comparative adaptation to hypoxia 

Session 2: MET 212 

Human altitude adaptation and maladaptation

2:45 - 3:45 PM

Session 3: MET 213

Consequences of hypoxia on brain function 

Session 4: MET 214 
Chronic and intermittent hypoxia disease states and potential therapeutics 

Post-Summit Opportunities

Stay connected with the Center for Physiological Genomics of Low Oxygen.

1. Contribute a paragraph for a paper.

Summarize a) what is known and/or b) what remains to be answered about Topics covered in the Presentation and the Breakout Sessions at the Summit. 

Provide one sentence regarding future directions relevant to the following Topics and ways they could be tested using innovative, cross-disciplinary approaches for hypoxia research:
- Epigenetics & early life environments 
- Altitude adaptation & maladaptation 
- Consequences of hypoxia on physiology 
- Comparative physiology & genomics of hypoxia.

Each paragraph will be synthesized into a paper that describes how Summit ideas fit into various time domains of “adaptation” to low oxygen. This could span 100s of millions of years (comparative) to thousands of years ago (modern human adaptation over many generations) to present-day adaptations/mal-adaptations (i.e., epigeneticsand/or phenotype variation in hypoxia-related disease states such as sleep apnea). 

2. Participate in a CPGLO grant meet-up group. 

Please email Specific Aims from your Grant Meet-up group to by June 2, 2017.  

In your message, please 1) include a quote for specific equipment (up to $5000) that will support the collection of preliminary data for your proposal and 2) indicate how this resource will be used by various CPGLO participants. 

CPGLO Co-Directors will announce the 2017 CPGLO Seed Funding Award in late June.

CPGLO Summit 2016 

Please visit our wikispaces site for information regarding the 2016 CPGLO Summit.

CPGLO Concept and Vocabulary List