The overall aim of CPGLO is to maximize information from highly informative but currently separate social and biological (anthropological, physiological, -omic, clinical) research.
The Center specifically focuses on important but understudied questions regarding human responses to low oxygen, including:
Genomic and systems-level physiological and molecular data collected and analyzed through separate but highly integrated components of the center aim to address these concerns at basic and clinical research levels.
how variation is distributed among different ancestral groups,
how this variation influences or reflects system-wide differences in oxygen transport, and
how these differences ultimately contribute to distinct responses to low oxygen (hypoxia) inherent to many common disease states.