Monday, June 28, 2021,
noon to 1:00 pm PST
Online Only (Zoom Meeting)
Jorge A. Bezerra, M.D.
Professor of Pediatrics
Cincinnati Children's Hospital Medical Center
The William and Rebecca Balistreri Chair in Pediatric Hepatology
Director, Division of Gastroenterology, Hepatology, and Nutrition
Medical Director, Liver Care Center
Director, Digestive Health Center
The INs(ide) and OUTs(ide) regulation of cholangiocyte survival
Speaker’s Research Interests: Dr. Bezerra investigates regulatory mechanisms of liver and biliary injury. One major research focus is preclinical and translational research on biliary atresia which is the most common cause of chronic liver disease in children. Dr. Bezerra's laboratory identified key regulatory functions for hepatic dendritic cells and CD8+ and NK lymphocytes in recognition and induction of injury to the bile duct epithelium. Ongoing experiments are identifying costimulatory signals controlling cell survival during early postnatal development and small molecules regulating biliary diseases.
Monday, July 26, 2021, noon to 1:00 pm PST
Jack A. Gilbert, Ph.D.
Department of Pediatrics and Scripps Institution of Oceanography
UC San Diego School of Medicine
San Diego, CA
Speaker's Research Interests: Dr. Gilbert’s research is focused on understanding how to apply advances in microbiome research into the clinic. A key aspect of this work is the appropriate screening of microbiome profiles from various environments, such as biopsies. His primary research foci are the gut microbiome and lung microbiome, where mucosal biopsies present with major human DNA contamination.
Monday, August 30, 2021
Maria T. Abreu, M.D.
Director, Crohn's & Colitis Center
Professor of Medicine
Professor of Microbiology and Immunology
Vice Chair for Research, Department of Medicine
Speaker's Research Interests
University of Miami
: The research focus of Dr. Abreu's laboratory is inflammatory bowel diseases (IBD) and colon cancer. Dr. Abreu has a special interest in the intimate relationship between the intestinal mucosa of the human host and its associated intestinal microbiota. In particular, her laboratory is testing the hypothesis that innate immune receptors that recognize bacteria activate intestinal epithelial cells to proliferate promoting colitis-associated cancer.
Monday, September 27, 2021
David E. Cohen, M.D, Ph.D.
Vincent Astor Distinguished Professor of Medicine
Chief, Division of Gastroenterology and Hepatology
Joan & Sanford I. Weill Department of Medicine
Weill Cornell Medicine
Speaker's Research Interests
New York, NY
: Dr. Cohen’s research focuses on the mechanisms whereby hydrophobic lipid molecules regulate nutrient metabolism and energy homeostasis. His laboratory seeks to identify new molecular targets that could be leveraged in the management of obesity and its common metabolic complications, including non-alcoholic fatty liver disease and type 2 diabetes. Dr. Cohen’s research interests further include identifying a role for the gut microbiome in regulating thermogenesis and energy expenditure in mice.
Monday, October 25, 2021
Wolfram Goessling, M.D, Ph.D.
Robert H. Ebert Professor of Medicine
Harvard Medical School
Jules L. Dienstag MD and Betty and Newell Hale Endowed Chair in Gastroenterology
Chief, Division of Gastroenterology, Massachusetts General Hospital
Speaker’s Research Interests: Dr. Goessling’s laboratory studies regulators of liver development to explore endodermal progenitor cell specification, organ differentiation, and growth. The main focus of the research is to understand the signals that indicate organ injury and regulate growth and regeneration. The inability to recover from acute injury can lead to organ failure, while a dysregulated regenerative response in the setting of chronic injury may contribute to cancer formation. Zebrafish is investigated as the primary model to discover novel regulatory pathways of liver development and evaluate their importance for recovery after toxic and physical injury.
Tuesday, November 30, 2021, 7:30 am to 8:30 am
Hashem B. El-Serag, M.D., M.P.H.
Chairman and Professor, Department of Medicine, Gastroenterology
Director, Texas Medical Center Digestive Diseases Center
Baylor College of Medicine
Speaker’s research Interests: Dr. El-Serag's research focuses on the epidemiology of digestive disorders, especially chronic liver disease, liver cancer and Barrett’s esophagus. His research was the first report of the rising trends in HCC incidence and its mortality and later work was among the first to report the connection between hepatitis C and HCC. His work on esophageal adenocarcinoma and its precursor lesion, Barrett’s esophagus, was important for reporting on rising GERD rates and the link between obesity and EAC, as well as for uncovering the inverse association between H pylori infection and the risk of Barrett’s esophagus and esophageal adenocarcinoma.
Monday, December 13, 2021
Eugene B. Chang, M.D.
Martin Boyer Distinguished Professor of Medicine
Director, Microbiome Medicine Program
Department of Medicine
Knapp Center for Biomedical Discovery
University of Chicago
Speaker’s Research Interests
: Dr. Chang’s research is directed towards gaining a better understanding of what factors are involved in the selection and assembly of intestinal microbes, and how they can be used to reshape the enteric microbiome to prevent and treat disease. The focus of Dr. Chang’s research is the study of host-microbe interactions in the context of human and mammalian systems and the bidirectional signaling processes that mediate these interactions.