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Publications

Link to a full list of publications on PubMed [Click Here]

Released on PrePriNT [Click here for a complete list of releases on BioRxiv]

Design principles of dose-response alignment in coupled GTPase switches
Lingxia Qiao, Pradipta Ghosh, Padmini Rangamani
bioRxiv 2022.06.14.496184; doi: https://doi.org/10.1101/2022.06.14.496184

Coupling of NOD2 to GIV is Required for Bacterial Sensing
Gajanan D. Katkar, Mahitha Shree Anandachar, Saptarshi Sinha, Stella-Rita Ibeawuchi, Celia R. Espinoza, Jane Coates, Yashaswat S. Malhotra, Madhubanti Mullick, Vanessa Castillo, Daniella T. Vo, Debashis Sahoo, Pradipta Ghosh
bioRxiv 2022.04.26.489574; doi: https://doi.org/10.1101/2022.04.26.489574


AI-assisted Discovery of an Ethnicity-influenced Driver of Cell Transformation in Esophageal and Gastroesophageal Junction Adenocarcinomas
Pradipta Ghosh, Vinicius J. Campos, Daniella T. Vo, Caitlin Guccione, Vanae Goheen-Holland, Courtney Tindle, Guilherme S. Mazzini, Yudou He, Ludmil Alexandrov, Scott M. Lippman, Richard R. Gurski, Soumita Das, Rena Yadlapati, Kit Curtius, Debashis Sahoo
bioRxiv 2022.01.30.478408; doi: https://doi.org/10.1101/2022.01.30.478408


A Eukaryotic Circuit for Secretion-coupled Cellular Autonomy
Lingxia Qiao, Amer Ali Abd El-Hafeez, I-Chung Lo, Saptarshi Sinha, Krishna K. Midde, Tony Ngo, Nicolas Aznar, Inmaculada Lopez-Sanchez, Vijay Gupta, Marilyn G. Farquhar, Padmini Rangamani, Pradipta Ghosh
bioRxiv 2021.03.18.436048; doi: https://doi.org/10.1101/2021.03.18.436048

Regulation of DNA damage response by trimeric G-protein Signaling
Amer Ali Abd El-Hafeez, Nina Sun, Anirban Chakraborty, Jason Ear, Suchismita Roy, Pranavi Chamarthi, Navin Rajapakse, Soumita Das, Kathryn E. Luker, Tapas K. Hazra, Gary D. Luker, Pradipta Ghosh
bioRxiv 2021.07.21.452842; doi: https://doi.org/10.1101/2021.07.21.452842


COVID-19 lung disease shares driver AT2 cytopathic features with Idiopathic pulmonary fibrosis
Saptarshi Sinha, Vanessa Castillo, Celia R. Espinoza, Courtney Tindle, Ayden G. Fonseca, Jennifer M. Dan, Gajanan D. Katkar, Soumita Das, Debashis Sahoo, Pradipta Ghosh
bioRxiv 2021.11.28.470269; doi: https://doi.org/10.1101/2021.11.28.470269

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Chronologically listed from Jan 1 - Jan 1 for each year.

2022- present:

101: Gonzalez CG, Mills RH, Kordahi MC, Carrillo-Terrazas M, Secaira-Morocho H,
Widjaja CE, Tsai MS, Mittal Y, Yee BA, Vargas F, Weldon K, Gauglitz JM,
Delaroque C, Sauceda C, Rossitto LA, Ackermann G, Humphrey G, Swafford AD,
Siegel CA, Buckey JC Jr, Raffals LE, Sadler C, Lindholm P, Fisch KM, Valaseck M,
Suriawinata A, Yeo GW, Ghosh P, Chang JT, Chu H, Dorrestein P, Zhu Q, Chassaing
B, Knight R, Gonzalez DJ, Dulai PS. The Host-Microbiome Response to Hyperbaric
Oxygen Therapy in Ulcerative Colitis Patients. Cell Mol Gastroenterol Hepatol.
2022 Apr 1:S2352-345X(22)00060-1. doi: 10.1016/j.jcmgh.2022.03.008. Epub ahead
of print. PMID: 35378331.

102: Katkar GD, Sayed IM, Anandachar MS, Castillo V, Vidales E, Toobian D, Usmani
F, Sawires JR, Leriche G, Yang J, Sandborn WJ, Das S, Sahoo D, Ghosh P.
Artificial intelligence-rationalized balanced PPARα/γ dual agonism resets
dysregulated macrophage processes in inflammatory bowel disease. Commun Biol.
2022 Mar 14;5(1):231. doi: 10.1038/s42003-022-03168-4. PMID: 35288651; PMCID:
PMC8921270.

103: Elbadawi MM, Eldehna WM, Abd El-Hafeez AA, Somaa WR, Albohy A, Al-Rashood ST,
Agama KK, Elkaeed EB, Ghosh P, Pommier Y, Abe M. 2-Arylquinolines as novel
anticancer agents with dual EGFR/FAK kinase inhibitory activity: synthesis,
biological evaluation, and molecular modelling insights. J Enzyme Inhib Med
Chem. 2022 Dec;37(1):349-372. doi: 10.1080/14756366.2021.2015344. Erratum in: J
Enzyme Inhib Med Chem. 2022 Dec;37(1):514. PMID: 34923887; PMCID: PMC8725837.

104: Sinha S, Castillo V, Espinoza CR, Tindle C, Fonseca AG, Dan JM, Katkar GD,
Das S, Sahoo D, Ghosh P. COVID-19 lung disease shares driver AT2 cytopathic
features with Idiopathic pulmonary fibrosis. bioRxiv [Preprint]. 2022 Feb
28:2021.11.28.470269. doi: 10.1101/2021.11.28.470269. PMID: 34873597; PMCID:
PMC8647648.

105. The DNA glycosylase NEIL2 plays a vital role in combating SARS-CoV-2 infection.
Hazra T, Tapryal N, Chakraborty A, Rayavara K, Wakamiya M, Islam A, Pan L, Hsu J, Tat V, Maruyama J, Hosoki K, Sayed I, Alcantara J, Castillo V, Tindle C, Sarker A, Cardenas V, Sharma G, Alexander LC, Sur S, Ghosh G, Paessler S, Sahoo D, Ghosh P, Das S, Boldogh I, Tseng CT.
Res Sq. 2022 May 27:rs.3.rs-1690354. doi: 10.21203/rs.3.rs-1690354/v1. Preprint.
PMID: 35665009

106. Ghosh P, Katkar GD, Shimizu C, Kim J, Khandelwal S, Tremoulet AH, Kanegaye JT; Pediatric Emergency Medicine Kawasaki Disease Research Group. An Artificial Intelligence-guided signature reveals the shared host immune response in MIS-C and Kawasaki disease. 
Nat Commun. 2022 May 16;13(1):2687. doi: 10.1038/s41467-022-30357-w.
PMID: 35577777

107. New 1,2,3-triazole linked ciprofloxacin-chalcones induce DNA damage by inhibiting human topoisomerase I& II and tubulin polymerization. Mohammed HHH, Abd El-Hafeez AA, Ebeid K, Mekkawy AI, Abourehab MAS, Wafa EI, Alhaj-Suliman SO, Salem AK, Ghosh P, Abuo-Rahma GEA, Hayallah AM, Abbas SH.
J Enzyme Inhib Med Chem. 2022 Dec;37(1):1346-1363. doi: 10.1080/14756366.2022.2072308.
PMID: 35548854

108. "Effects of iron modulation on mesenchymal stem cell-induced drug resistance in estrogen-receptor-positive breast cancer" by Gary Luker, Johanna Buschhaus, Shrila Rajendran, Brock Humphries, Alyssa Cutter, Ayşe Muñiz, Nicholas Ciavattone, Alexander Buschhaus, Tatiana Cañeque, Zeribe Nwosu, Debashis Sahoo, Avinash Bevoor, Yatrik Shah, Costas Lyssiotis, Pradipta Ghosh, Max Wicha, and Raphaël Rodriguez [Accepted, In Press, Oncogene; 2022; Paper #ONC-2022-00536RR],  
 

2021-2022:

91: Elghazawy H, Bakkach J, Helal T, Aref AM, Kelany M, Abdallah LE, Abdelbakey
FS, Ali D, Ali DZ, Ahmed MO, El-Hafeez AAA, Ghosh P, Alorabi MO. Clinico-
pathological relationship between androgen receptor and tumour infiltrating
lymphocytes in triple negative breast cancer. Ecancermedicalscience. 2021 Nov
11;15:1317. doi: 10.3332/ecancer.2021.1317. PMID: 35047068; PMCID: PMC8723750.

92: Toobian D, Ghosh P, Katkar GD. Parsing the Role of PPARs in Macrophage
Processes. Front Immunol. 2021 Dec 22;12:783780. doi: 10.3389/fimmu.2021.783780.
PMID: 35003101; PMCID: PMC8727354.

93: Long T, Abbasi N, Hernandez JE, Li Y, Sayed IM, Ma S, Iemolo A, Yee BA, Yeo
GW, Telese F, Ghosh P, Das S, Huang WJM. RNA binding protein DDX5 directs tuft
cell specification and function to regulate microbial repertoire and disease
susceptibility in the intestine. Gut. 2021 Dec 1:gutjnl-2021-324984. doi:
10.1136/gutjnl-2021-324984. Epub ahead of print. PMID: 34853057.

94: Vo DT, Fuller MR, Tindle C, Anandachar MS, Das S, Sahoo D, Ghosh P. SPT6 loss
permits the transdifferentiation of keratinocytes into an intestinal fate that
resembles Barrett's metaplasia. iScience. 2021 Sep 11;24(10):103121. doi:
10.1016/j.isci.2021.103121. PMID: 34622168; PMCID: PMC8481972.

95: Tindle C, Fuller M, Fonseca A, Taheri S, Ibeawuchi SR, Beutler N, Katkar GD,
Claire A, Castillo V, Hernandez M, Russo H, Duran J, Crotty Alexander LE, Tipps
A, Lin G, Thistlethwaite PA, Chattopadhyay R, Rogers TF, Sahoo D, Ghosh P, Das
S. Adult stem cell-derived complete lung organoid models emulate lung disease in
COVID-19. Elife. 2021 Aug 13;10:e66417. doi: 10.7554/eLife.66417. PMID:
34463615; PMCID: PMC8463074.

96: Reynoso S, Castillo V, Katkar GD, Lopez-Sanchez I, Taheri S, Espinoza C,
Rohena C, Sahoo D, Gagneux P, Ghosh P. GIV/Girdin, a non-receptor modulator for
Gαi/s, regulates spatiotemporal signaling during sperm capacitation and is
required for male fertility. Elife. 2021 Aug 19;10:e69160. doi:
10.7554/eLife.69160. PMID: 34409938; PMCID: PMC8376251.

97: Mustafa M, Abd El-Hafeez AA, Abdelhafeez DA, Abdelhamid D, Mostafa YA, Ghosh
P, Hayallah AM, A Abuo-Rahma GE. FAK inhibitors as promising anticancer targets:
present and future directions. Future Med Chem. 2021 Sep;13(18):1559-1590. doi:
10.4155/fmc-2021-0015. Epub 2021 Aug 3. PMID: 34340532; PMCID: PMC8386514.

98: Sayed IM, Tindle C, Fonseca AG, Ghosh P, Das S. Functional assays with human
patient-derived enteroid monolayers to assess the human gut barrier. STAR
Protoc. 2021 Jul 17;2(3):100680. doi: 10.1016/j.xpro.2021.100680. PMID:
34337445; PMCID: PMC8313751.

99: Sahoo D, Swanson L, Sayed IM, Katkar GD, Ibeawuchi SR, Mittal Y, Pranadinata
RF, Tindle C, Fuller M, Stec DL, Chang JT, Sandborn WJ, Das S, Ghosh P.
Artificial intelligence guided discovery of a barrier-protective therapy in
inflammatory bowel disease. Nat Commun. 2021 Jul 12;12(1):4246. doi:
10.1038/s41467-021-24470-5. PMID: 34253728; PMCID: PMC8275683.

100: Saul S, Karim M, Huang PT, Ghita L, Chiu W, Kumar S, Bhalla N, Leyssen P,
Cohen CA, Huie K, Tindle C, Sibai M, Pinsky BA, Das S, Ghosh P, Dye JM, Solow-
Cordero DE, Jin J, Jochmans D, Neyts J, Narayanan A, De Jonghe S, Einav S.
Discovery of pan-ErbB inhibitors protecting from SARS-CoV-2 replication,
inflammation, and lung injury by a drug repurposing screen. bioRxiv [Preprint].
2021 Jun 15:2021.05.15.444128. doi: 10.1101/2021.05.15.444128. PMID: 34159337;
PMCID: PMC8219101.


2020-2021:

81: Elghazawy H, Bakkach J, Helal T, Aref AM, Kelany M, Abdallah LE, Abdelbakey
FS, Ali D, Ali DZ, Ahmed MO, El-Hafeez AAA, Ghosh P, Alorabi MO. Clinico-
pathological relationship between androgen receptor and tumour infiltrating
lymphocytes in triple negative breast cancer. Ecancermedicalscience. 2021 Nov
11;15:1317. doi: 10.3332/ecancer.2021.1317. PMID: 35047068; PMCID: PMC8723750.

82: Toobian D, Ghosh P, Katkar GD. Parsing the Role of PPARs in Macrophage
Processes. Front Immunol. 2021 Dec 22;12:783780. doi: 10.3389/fimmu.2021.783780.
PMID: 35003101; PMCID: PMC8727354.

83: Sayed IM, El-Hafeez AAA, Maity PP, Das S, Ghosh P. Modeling colorectal
cancers using multidimensional organoids. Adv Cancer Res. 2021;151:345-383. doi:
10.1016/bs.acr.2021.02.005. Epub 2021 Mar 26. PMID: 34148617; PMCID: PMC8221168.

84: Loutfy SA, Abdallah ZF, Shaalan M, Moneer M, Karam A, Moneer MM, Sayed IM,
Abd El-Hafeez AA, Ghosh P, Zekri AN. Prevalence of MMTV-Like <i>env</i>
Sequences and Its Association with BRCA1/2 Genes Mutations Among Egyptian Breast
Cancer Patients. Cancer Manag Res. 2021 Mar 26;13:2835-2848. doi:
10.2147/CMAR.S294584. PMID: 33814932; PMCID: PMC8009344.

85: Ear J, Abd El-Hafeez AA, Roy S, Ngo T, Rajapakse N, Choi J, Khandelwal S,
Ghassemian M, McCaffrey L, Kufareva I, Sahoo D, Ghosh P. A long isoform of
GIV/Girdin contains a PDZ-binding module that regulates localization and
G-protein binding. J Biol Chem. 2021 Jan-Jun;296:100493. doi:
10.1016/j.jbc.2021.100493. Epub 2021 Mar 3. PMID: 33675748; PMCID: PMC8042451.

86: Shigeyasu K, Toden S, Ozawa T, Matsuyama T, Nagasaka T, Ishikawa T, Sahoo D,
Ghosh P, Uetake H, Fujiwara T, Goel A. The PVT1 lncRNA is a novel epigenetic
enhancer of MYC, and a promising risk-stratification biomarker in colorectal
cancer. Mol Cancer. 2020 Nov 5;19(1):155. doi: 10.1186/s12943-020-01277-4. PMID:
33148262; PMCID: PMC7643275.

87: Kalogriopoulos NA, Lopez-Sanchez I, Lin C, Ngo T, Midde KK, Roy S, Aznar N,
Murray F, Garcia-Marcos M, Kufareva I, Ghassemian M, Ghosh P. Receptor tyrosine
kinases activate heterotrimeric G proteins via phosphorylation within the
interdomain cleft of Gαi. Proc Natl Acad Sci U S A. 2020 Nov
17;117(46):28763-28774. doi: 10.1073/pnas.2004699117. Epub 2020 Nov 2. PMID:
33139573; PMCID: PMC7682395.

88: Swanson L, Katkar GD, Tam J, Pranadinata RF, Chareddy Y, Coates J, Anandachar
MS, Castillo V, Olson J, Nizet V, Kufareva I, Das S, Ghosh P. TLR4 signaling and
macrophage inflammatory responses are dampened by GIV/Girdin. Proc Natl Acad Sci
U S A. 2020 Oct 27;117(43):26895-26906. doi: 10.1073/pnas.2011667117. Epub 2020
Oct 14. PMID: 33055214; PMCID: PMC7604444.

89: Sayed IM, Chakraborty A, Abd El-Hafeez AA, Sharma A, Sahan AZ, Huang WJM,
Sahoo D, Ghosh P, Hazra TK, Das S. The DNA Glycosylase NEIL2 Suppresses
<i>Fusobacterium</i>-Infection-Induced Inflammation and DNA Damage in Colonic
Epithelial Cells. Cells. 2020 Aug 28;9(9):1980. doi: 10.3390/cells9091980. PMID:
32872214; PMCID: PMC7565382.

90: Abbasi N, Long T, Li Y, Yee BA, Cho BS, Hernandez JE, Ma E, Patel PR, Sahoo
D, Sayed IM, Varki N, Das S, Ghosh P, Yeo GW, Huang WJM. DDX5 promotes oncogene
C3 and FABP1 expressions and drives intestinal inflammation and tumorigenesis.
Life Sci Alliance. 2020 Aug 18;3(10):e202000772. doi: 10.26508/lsa.202000772.
PMID: 32817263; PMCID: PMC7441524.


2019-2020:

72: Dang D, Taheri S, Das S, Ghosh P, Prince LS, Sahoo D. Computational Approach
to Identifying Universal Macrophage Biomarkers. Front Physiol. 2020 Apr
8;11:275. doi: 10.3389/fphys.2020.00275. PMID: 32322218; PMCID: PMC7156600.

73: Demb J, Yaseyyedi A, Liu L, Bustamante R, Earles A, Ghosh P, Gutkind JS,
Gawron AJ, Kaltenbach TR, Martinez ME, Gupta S. Metformin Is Associated With
Reduced Odds for Colorectal Cancer Among Persons With Diabetes. Clin Transl
Gastroenterol. 2019 Nov;10(11):e00092. doi: 10.14309/ctg.0000000000000092. PMID:
31770138; PMCID: PMC6890275.

74: Ghosh P, Garcia-Marcos M. Do All Roads Lead to Rome in G-Protein Activation?
Trends Biochem Sci. 2020 Mar;45(3):182-184. doi: 10.1016/j.tibs.2019.10.010.
Epub 2019 Nov 18. PMID: 31753703; PMCID: PMC7147754.

75: Limso C, Ngo JM, Nguyen P, Leal S, Husain A, Sahoo D, Ghosh P, Bhandari D.
The Gα-interacting vesicle-associated protein interacts with and promotes cell
surface localization of GRP78 during endoplasmic reticulum stress. FEBS Lett.
2020 Mar;594(6):1088-1100. doi: 10.1002/1873-3468.13685. Epub 2019 Nov 30. PMID:
31736058; PMCID: PMC7093220.

76: Jansen AML, Ghosh P, Dakal TC, Slavin TP, Boland CR, Goel A. Novel candidates
in early-onset familial colorectal cancer. Fam Cancer. 2020 Jan;19(1):1-10. doi:
10.1007/s10689-019-00145-5. Epub 2019 Sep 25. PMID: 31555933; PMCID: PMC7241873.

77: Saha S, Siddiqui SS, Khan N, Verhagen A, Jiang W, Springer S, Ghosh P, Varki
A. Controversies about the subcellular localization and mechanisms of action of
the Alzheimer's disease-protective CD33 splice variant. Acta Neuropathol. 2019
Oct;138(4):671-672. doi: 10.1007/s00401-019-02065-1. Epub 2019 Aug 22. PMID:
31440824.

78: Ear J, Dunkel Y, Mittal Y, Lim BBC, Liu L, Holda MK, Nitsche U, Barbazán J,
Goel A, Janssen KP, Aznar N, Ghosh P. Two Isoforms of the Guanine Nucleotide
Exchange Factor, Daple/CCDC88C Cooperate as Tumor Suppressors. Sci Rep. 2019 Aug
20;9(1):12124. doi: 10.1038/s41598-019-48420-w. PMID: 31431650; PMCID:
PMC6702192.

79: Kalogriopoulos NA, Rees SD, Ngo T, Kopcho NJ, Ilatovskiy AV, Sun N, Komives
EA, Chang G, Ghosh P, Kufareva I. Structural basis for GPCR-independent
activation of heterotrimeric Gi proteins. Proc Natl Acad Sci U S A. 2019 Aug
13;116(33):16394-16403. doi: 10.1073/pnas.1906658116. Epub 2019 Jul 30. Erratum
in: Proc Natl Acad Sci U S A. 2019 Oct 8;116(41):20794. PMID: 31363053; PMCID:
PMC6697900.

80: Getz M, Swanson L, Sahoo D, Ghosh P, Rangamani P. A predictive computational
model reveals that GIV/girdin serves as a tunable valve for EGFR-stimulated
cyclic AMP signals. Mol Biol Cell. 2019 Jun 15;30(13):1621-1633. doi:
10.1091/mbc.E18-10-0630. Epub 2019 Apr 24. PMID: 31017840; PMCID: PMC6727633.


2018-2019:

69: Dunkel Y, Reid AL, Ear J, Aznar N, Millward M, Gray E, Pearce R, Ziman M,
Ghosh P. Prognostic Relevance of CCDC88C (Daple) Transcripts in the Peripheral
Blood of Patients with Cutaneous Melanoma. Sci Rep. 2018 Dec 21;8(1):18036. doi:
10.1038/s41598-018-36173-x. PMID: 30575751; PMCID: PMC6303298.

70: Midde K, Sun N, Rohena C, Joosen L, Dhillon H, Ghosh P. Single-Cell Imaging
of Metastatic Potential of Cancer Cells. iScience. 2018 Dec 21;10:53-65. doi:
10.1016/j.isci.2018.11.022. Epub 2018 Nov 15. PMID: 30500482; PMCID: PMC6263091.

71: Aznar N, Ear J, Dunkel Y, Sun N, Satterfield K, He F, Kalogriopoulos NA,
Lopez-Sanchez I, Ghassemian M, Sahoo D, Kufareva I, Ghosh P. Convergence of Wnt,
growth factor, and heterotrimeric G protein signals on the guanine nucleotide
exchange factor Daple. Sci Signal. 2018 Feb 27;11(519):eaao4220. doi:
10.1126/scisignal.aao4220. PMID: 29487190; PMCID: PMC5862031.


2017-2018:

64: Aznar N, Sun N, Dunkel Y, Ear J, Buschman MD, Ghosh P. A Daple-Akt feed-
forward loop enhances noncanonical Wnt signals by compartmentalizing β-catenin.
Mol Biol Cell. 2017 Dec 1;28(25):3709-3723. doi: 10.1091/mbc.E17-06-0405. Epub
2017 Oct 11. PMID: 29021338; PMCID: PMC5706997.

65: Siddiqui SS, Springer SA, Verhagen A, Sundaramurthy V, Alisson-Silva F, Jiang
W, Ghosh P, Varki A. The Alzheimer's disease-protective CD33 splice variant
mediates adaptive loss of function via diversion to an intracellular pool. J
Biol Chem. 2017 Sep 15;292(37):15312-15320. doi: 10.1074/jbc.M117.799346. Epub
2017 Jul 26. PMID: 28747436; PMCID: PMC5602391.

66: Lizcano A, Secundino I, Döhrmann S, Corriden R, Rohena C, Diaz S, Ghosh P,
Deng L, Nizet V, Varki A. Erythrocyte sialoglycoproteins engage Siglec-9 on
neutrophils to suppress activation. Blood. 2017 Jun 8;129(23):3100-3110. doi:
10.1182/blood-2016-11-751636. Epub 2017 Apr 17. PMID: 28416510; PMCID:
PMC5465837.

67: Ghosh P, Rangamani P, Kufareva I. The GAPs, GEFs, GDIs and…now, GEMs: New
kids on the heterotrimeric G protein signaling block. Cell Cycle. 2017 Apr
3;16(7):607-612. doi: 10.1080/15384101.2017.1282584. Epub 2017 Mar 13. PMID:
28287365; PMCID: PMC5397260.

68: Ghosh P. The stress polarity pathway: AMPK 'GIV'-es protection against
metabolic insults. Aging (Albany NY). 2017 Feb 15;9(2):303-314. doi:
10.18632/aging.101179. PMID: 28209925; PMCID: PMC5361665. 


2016-2017:

54: Ghosh P, Aznar N, Swanson L, Lo IC, Lopez-Sanchez I, Ear J, Rohena C,
Kalogriopoulos N, Joosen L, Dunkel Y, Sun N, Nguyen P, Bhandari D. Biochemical,
Biophysical and Cellular Techniques to Study the Guanine Nucleotide Exchange
Factor, GIV/Girdin. Curr Protoc Chem Biol. 2016 Dec 7;8(4):265-298. doi:
10.1002/cpch.13. PMID: 27925669; PMCID: PMC5154557.

55: Aznar N, Patel A, Rohena CC, Dunkel Y, Joosen LP, Taupin V, Kufareva I,
Farquhar MG, Ghosh P. AMP-activated protein kinase fortifies epithelial tight
junctions during energetic stress via its effector GIV/Girdin. Elife. 2016 Nov
4;5:e20795. doi: 10.7554/eLife.20795. PMID: 27813479; PMCID: PMC5119889.

56: Dunkel Y, Diao K, Aznar N, Swanson L, Liu L, Zhu W, Mi XY, Ghosh P.
Prognostic impact of total and tyrosine phosphorylated GIV/Girdin in breast
cancers. FASEB J. 2016 Nov;30(11):3702-3713. doi: 10.1096/fj.201600500. Epub
2016 Jul 20. PMID: 27440794; PMCID: PMC5067257.

57: Gupta V, Bhandari D, Leyme A, Aznar N, Midde KK, Lo IC, Ear J, Niesman I,
López-Sánchez I, Blanco-Canosa JB, von Zastrow M, Garcia-Marcos M, Farquhar MG,
Ghosh P. GIV/Girdin activates Gαi and inhibits Gαs via the same motif. Proc Natl
Acad Sci U S A. 2016 Sep 27;113(39):E5721-30. doi: 10.1073/pnas.1609502113. Epub
2016 Sep 12. PMID: 27621449; PMCID: PMC5047194.

58: Banerjee Mustafi S, Aznar N, Dwivedi SK, Chakraborty PK, Basak R, Mukherjee
P, Ghosh P, Bhattacharya R. Mitochondrial BMI1 maintains bioenergetic
homeostasis in cells. FASEB J. 2016 Dec;30(12):4042-4055. doi:
10.1096/fj.201600321R. Epub 2016 Sep 9. PMID: 27613804; PMCID: PMC5102112.

59: El Ghazal R, Yin X, Johns SC, Swanson L, Macal M, Ghosh P, Zuniga EI, Fuster
MM. Glycan Sulfation Modulates Dendritic Cell Biology and Tumor Growth.
Neoplasia. 2016 May;18(5):294-306. doi: 10.1016/j.neo.2016.04.004. PMID:
27237321; PMCID: PMC4887599.

60: Ghosh P, Tie J, Muranyi A, Singh S, Brunhoeber P, Leith K, Bowermaster R,
Liao Z, Zhu Y, LaFleur B, Tran B, Desai J, Jones I, Croxford M, Jover R, Goel A,
Waring P, Hu S, Teichgraber V, Rohr UP, Ridder R, Shanmugam K, Gibbs P. Girdin
(GIV) Expression as a Prognostic Marker of Recurrence in Mismatch Repair-
Proficient Stage II Colon Cancer. Clin Cancer Res. 2016 Jul 15;22(14):3488-98.
doi: 10.1158/1078-0432.CCR-15-2290. Epub 2016 Mar 30. PMID: 27029492; PMCID:
PMC4947424.

61: Barbazan J, Dunkel Y, Li H, Nitsche U, Janssen KP, Messer K, Ghosh P.
Prognostic Impact of Modulators of G proteins in Circulating Tumor Cells from
Patients with Metastatic Colorectal Cancer. Sci Rep. 2016 Feb 26;6:22112. doi:
10.1038/srep22112. PMID: 26916336; PMCID: PMC4768264.

62: Aznar N, Kalogriopoulos N, Midde KK, Ghosh P. Heterotrimeric G protein
signaling via GIV/Girdin: Breaking the rules of engagement, space, and time.
Bioessays. 2016 Apr;38(4):379-93. doi: 10.1002/bies.201500133. Epub 2016 Feb 16.
PMID: 26879989; PMCID: PMC5123561.

63: Ghosh P. The untapped potential of tyrosine-based G protein signaling.
Pharmacol Res. 2016 Mar;105:99-107. doi: 10.1016/j.phrs.2016.01.017. Epub 2016
Jan 22. PMID: 26808081; PMCID: PMC4775314.


2015-2016:

44: Lopez-Sanchez I, Ma GS, Pedram S, Kalogriopoulos N, Ghosh P. GIV/girdin binds
exocyst subunit-Exo70 and regulates exocytosis of GLUT4 storage vesicles.
Biochem Biophys Res Commun. 2015 Dec 4-11;468(1-2):287-93. doi:
10.1016/j.bbrc.2015.10.111. Epub 2015 Oct 26. PMID: 26514725; PMCID: PMC4659757.

45: Lopez-Sanchez I, Kalogriopoulos N, Lo IC, Kabir F, Midde KK, Wang H, Ghosh P.
Focal adhesions are foci for tyrosine-based signal transduction via GIV/Girdin
and G proteins. Mol Biol Cell. 2015 Dec 1;26(24):4313-24. doi:
10.1091/mbc.E15-07-0496. Epub 2015 Oct 7. PMID: 26446841; PMCID: PMC4666128.

46: Ma GS, Lopez-Sanchez I, Aznar N, Kalogriopoulos N, Pedram S, Midde K,
Ciaraldi TP, Henry RR, Ghosh P. Activation of G proteins by GIV-GEF is a pivot
point for insulin resistance and sensitivity. Mol Biol Cell. 2015 Nov
15;26(23):4209-23. doi: 10.1091/mbc.E15-08-0553. Epub 2015 Sep 16. PMID:
26378251; PMCID: PMC4642855.

47: Bhandari D, Lopez-Sanchez I, To A, Lo IC, Aznar N, Leyme A, Gupta V, Niesman
I, Maddox AL, Garcia-Marcos M, Farquhar MG, Ghosh P. Cyclin-dependent kinase 5
activates guanine nucleotide exchange factor GIV/Girdin to orchestrate
migration-proliferation dichotomy. Proc Natl Acad Sci U S A. 2015 Sep
1;112(35):E4874-83. doi: 10.1073/pnas.1514157112. Epub 2015 Aug 18. PMID:
26286990; PMCID: PMC4568279.

48: Ghosh P. Heterotrimeric G proteins as emerging targets for network based
therapy in cancer: End of a long futile campaign striking heads of a Hydra.
Aging (Albany NY). 2015 Jul;7(7):469-74. doi: 10.18632/aging.100781. PMID:
26224586; PMCID: PMC4543036.

49: Aznar N, Midde KK, Dunkel Y, Lopez-Sanchez I, Pavlova Y, Marivin A, Barbazán
J, Murray F, Nitsche U, Janssen KP, Willert K, Goel A, Abal M, Garcia-Marcos M,
Ghosh P. Daple is a novel non-receptor GEF required for trimeric G protein
activation in Wnt signaling. Elife. 2015 Jun 30;4:e07091. doi:
10.7554/eLife.07091. PMID: 26126266; PMCID: PMC4484057.

50: Ghosh P. G protein coupled growth factor receptor tyrosine kinase: no longer
an oxymoron. Cell Cycle. 2015;14(16):2561-5. doi: 10.1080/15384101.2015.1066538.
Epub 2015 Jun 30. PMID: 26126131; PMCID: PMC4613836.

51: Ma GS, Aznar N, Kalogriopoulos N, Midde KK, Lopez-Sanchez I, Sato E, Dunkel
Y, Gallo RL, Ghosh P. Therapeutic effects of cell-permeant peptides that
activate G proteins downstream of growth factors. Proc Natl Acad Sci U S A. 2015
May 19;112(20):E2602-10. doi: 10.1073/pnas.1505543112. Epub 2015 Apr 29. PMID:
25926659; PMCID: PMC4443320.

52: Lo IC, Gupta V, Midde KK, Taupin V, Lopez-Sanchez I, Kufareva I, Abagyan R,
Randazzo PA, Farquhar MG, Ghosh P. Activation of Gαi at the Golgi by GIV/Girdin
imposes finiteness in Arf1 signaling. Dev Cell. 2015 Apr 20;33(2):189-203. doi:
10.1016/j.devcel.2015.02.009. Epub 2015 Apr 9. PMID: 25865347; PMCID:
PMC4415880.

53: Midde KK, Aznar N, Laederich MB, Ma GS, Kunkel MT, Newton AC, Ghosh P.
Multimodular biosensors reveal a novel platform for activation of G proteins by
growth factor receptors. Proc Natl Acad Sci U S A. 2015 Mar 3;112(9):E937-46.
doi: 10.1073/pnas.1420140112. Epub 2015 Feb 17. Erratum in: Proc Natl Acad Sci U
S A. 2015 Mar 24;112(12):E1509. PMID: 25713130; PMCID: PMC4352799.


2014-2015:

38: Ghosh P. G protein coupled growth factor receptor tyrosine kinase: no longer
an oxymoron. Cell Cycle. 2015;14(16):2561-5. doi: 10.1080/15384101.2015.1066538.
Epub 2015 Jun 30. PMID: 26126131; PMCID: PMC4613836.

39: Alakus H, Babicky ML, Ghosh P, Yost S, Jepsen K, Dai Y, Arias A, Samuels ML,
Mose ES, Schwab RB, Peterson MR, Lowy AM, Frazer KA, Harismendy O. Correction:
Genome-wide mutational landscape of mucinous carcinomatosis peritonei of
appendiceal origin. Genome Med. 2014 Jul 26;6(7):53. doi:
10.1186/s13073-014-0053-y. PMID: 25228923; PMCID: PMC4165363.

40: Lin C, Ear J, Midde K, Lopez-Sanchez I, Aznar N, Garcia-Marcos M, Kufareva I,
Abagyan R, Ghosh P. Structural basis for activation of trimeric Gi proteins by
multiple growth factor receptors via GIV/Girdin. Mol Biol Cell. 2014 Nov
5;25(22):3654-71. doi: 10.1091/mbc.E14-05-0978. Epub 2014 Sep 3. PMID: 25187647;
PMCID: PMC4230624.

41: Lopez-Sanchez I, Dunkel Y, Roh YS, Mittal Y, De Minicis S, Muranyi A, Singh
S, Shanmugam K, Aroonsakool N, Murray F, Ho SB, Seki E, Brenner DA, Ghosh P.
GIV/Girdin is a central hub for profibrogenic signalling networks during liver
fibrosis. Nat Commun. 2014 Jul 21;5:4451. doi: 10.1038/ncomms5451. PMID:
25043713; PMCID: PMC4107319.

42: Wang H, Misaki T, Taupin V, Eguchi A, Ghosh P, Farquhar MG. GIV/girdin links
vascular endothelial growth factor signaling to Akt survival signaling in
podocytes independent of nephrin. J Am Soc Nephrol. 2015 Feb;26(2):314-27. doi:
10.1681/ASN.2013090985. Epub 2014 Jul 10. PMID: 25012178; PMCID: PMC4310647.

43: Alakus H, Babicky ML, Ghosh P, Yost S, Jepsen K, Dai Y, Arias A, Samuels ML,
Mose ES, Schwab RB, Peterson MR, Lowy AM, Frazer KA, Harismendy O. Genome-wide
mutational landscape of mucinous carcinomatosis peritonei of appendiceal origin.
Genome Med. 2014 May 29;6(5):43. doi: 10.1186/gm559. PMID: 24944587; PMCID:
PMC4062050.


2013-2014:

34: Alakus H, Babicky ML, Ghosh P, Yost S, Jepsen K, Dai Y, Arias A, Samuels ML,
Mose ES, Schwab RB, Peterson MR, Lowy AM, Frazer KA, Harismendy O. Correction:
Genome-wide mutational landscape of mucinous carcinomatosis peritonei of
appendiceal origin. Genome Med. 2014 Jul 26;6(7):53. doi:
10.1186/s13073-014-0053-y. PMID: 25228923; PMCID: PMC4165363.

35: Alakus H, Babicky ML, Ghosh P, Yost S, Jepsen K, Dai Y, Arias A, Samuels ML,
Mose ES, Schwab RB, Peterson MR, Lowy AM, Frazer KA, Harismendy O. Genome-wide
mutational landscape of mucinous carcinomatosis peritonei of appendiceal origin.
Genome Med. 2014 May 29;6(5):43. doi: 10.1186/gm559. PMID: 24944587; PMCID:
PMC4062050.

36: Ghosh P, Cho M, Rawat G, Simkin PA, Gardner GC. Treatment of acute gouty
arthritis in complex hospitalized patients with anakinra. Arthritis Care Res
(Hoboken). 2013 Aug;65(8):1381-4. doi: 10.1002/acr.21989. PMID: 23650178.

37: López-Sánchez I, Garcia-Marcos M, Mittal Y, Aznar N, Farquhar MG, Ghosh P.
Protein kinase C-theta (PKCθ) phosphorylates and inhibits the guanine exchange
factor, GIV/Girdin. Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):5510-5. doi:
10.1073/pnas.1303392110. Epub 2013 Mar 18. PMID: 23509302; PMCID: PMC3619294.


2012-2013:

31: Dunkel Y, Ong A, Notani D, Mittal Y, Lam M, Mi X, Ghosh P. STAT3 protein up-
regulates Gα-interacting vesicle-associated protein (GIV)/Girdin expression, and
GIV enhances STAT3 activation in a positive feedback loop during wound healing
and tumor invasion/metastasis. J Biol Chem. 2012 Dec 7;287(50):41667-83. doi:
10.1074/jbc.M112.390781. Epub 2012 Oct 12. PMID: 23066027; PMCID: PMC3516717.

32: Klionsky DJ, et al.
Guidelines for the use and interpretation of assays for monitoring autophagy.
Autophagy. 2012 Apr;8(4):445-544. doi: 10.4161/auto.19496. PMID: 22966490;
PMCID: PMC3404883.

33: Garcia-Marcos M, Kietrsunthorn PS, Pavlova Y, Adia MA, Ghosh P, Farquhar MG.
Functional characterization of the guanine nucleotide exchange factor (GEF)
motif of GIV protein reveals a threshold effect in signaling. Proc Natl Acad Sci
U S A. 2012 Feb 7;109(6):1961-6. doi: 10.1073/pnas.1120538109. Epub 2012 Jan 25.
PMID: 22308453; PMCID: PMC3277514. 


2011-2012:

26: Lin C, Ear J, Pavlova Y, Mittal Y, Kufareva I, Ghassemian M, Abagyan R,
Garcia-Marcos M, Ghosh P. Tyrosine phosphorylation of the Gα-interacting protein
GIV promotes activation of phosphoinositide 3-kinase during cell migration. Sci
Signal. 2011 Sep 27;4(192):ra64. doi: 10.1126/scisignal.2002049. PMID: 21954290;
PMCID: PMC4226136.

27: Fukasawa H, Obayashi H, Schmieder S, Lee J, Ghosh P, Farquhar MG.
Phosphorylation of podocalyxin (Ser415) Prevents RhoA and ezrin activation and
disrupts its interaction with the actin cytoskeleton. Am J Pathol. 2011
Nov;179(5):2254-65. doi: 10.1016/j.ajpath.2011.07.046. Epub 2011 Sep 25. PMID:
21945805; PMCID: PMC3204015.

28: Mittal Y, Pavlova Y, Garcia-Marcos M, Ghosh P. Src homology domain
2-containing protein-tyrosine phosphatase-1 (SHP-1) binds and dephosphorylates
G(alpha)-interacting, vesicle-associated protein (GIV)/Girdin and attenuates the
GIV-phosphatidylinositol 3-kinase (PI3K)-Akt signaling pathway. J Biol Chem.
2011 Sep 16;286(37):32404-15. doi: 10.1074/jbc.M111.275685. Epub 2011 Jul 28.
PMID: 21799016; PMCID: PMC3173146.

29: Garcia-Marcos M, Kietrsunthorn PS, Wang H, Ghosh P, Farquhar MG. G Protein
binding sites on Calnuc (nucleobindin 1) and NUCB2 (nucleobindin 2) define a new
class of G(alpha)i-regulatory motifs. J Biol Chem. 2011 Aug 12;286(32):28138-49.
doi: 10.1074/jbc.M110.204099. Epub 2011 Jun 8. PMID: 21653697; PMCID:
PMC3151059.

30: Ghosh P, Garcia-Marcos M, Farquhar MG. GIV/Girdin is a rheostat that fine-
tunes growth factor signals during tumor progression. Cell Adh Migr. 2011 May-
Jun;5(3):237-48. doi: 10.4161/cam.5.3.15909. Epub 2011 May 1. PMID: 21546796;
PMCID: PMC3210208.


2010-2011:

22: Garcia-Marcos M, Jung BH, Ear J, Cabrera B, Carethers JM, Ghosh P. Expression
of GIV/Girdin, a metastasis-related protein, predicts patient survival in colon
cancer. FASEB J. 2011 Feb;25(2):590-9. doi: 10.1096/fj.10-167304. Epub 2010 Oct
25. PMID: 20974669; PMCID: PMC3023389.

23: Lee JK, Bhargava V, Mittal RK, Ghosh P. Achalasia, alcohol-stasis, and acute
necrotizing esophagitis: connecting the dots. Dig Dis Sci. 2011 Feb;56(2):612-4.
doi: 10.1007/s10620-010-1297-z. Epub 2010 Jun 16. PMID: 20552400; PMCID:
PMC3029818.

24: Ghosh P, Beas AO, Bornheimer SJ, Garcia-Marcos M, Forry EP, Johannson C, Ear
J, Jung BH, Cabrera B, Carethers JM, Farquhar MG. A G{alpha}i-GIV molecular
complex binds epidermal growth factor receptor and determines whether cells
migrate or proliferate. Mol Biol Cell. 2010 Jul 1;21(13):2338-54. doi:
10.1091/mbc.e10-01-0028. Epub 2010 May 12. PMID: 20462955; PMCID: PMC2893996.

25: Garcia-Marcos M, Ghosh P, Ear J, Farquhar MG. A structural determinant that
renders G alpha(i) sensitive to activation by GIV/girdin is required to promote
cell migration. J Biol Chem. 2010 Apr 23;285(17):12765-77. doi:
10.1074/jbc.M109.045161. Epub 2010 Feb 15. PMID: 20157114; PMCID: PMC2857069. 


2009-2010: 

22: Garcia-Marcos M, Ghosh P, Farquhar MG. GIV is a nonreceptor GEF for G alpha i
with a unique motif that regulates Akt signaling. Proc Natl Acad Sci U S A. 2009
Mar 3;106(9):3178-83. doi: 10.1073/pnas.0900294106. Epub 2009 Feb 11. PMID:
19211784; PMCID: PMC2651282.


2005-2009: Residency/Fellowship Training Period (not in lab)

11: Lee JK, Carethers JM, Ghosh P. ArterioVenous Malformation within Jejunal
Diverticulum: an unusual cause of massive gastrointestinal bleeding.
Gastroenterol Res Pract. 2009;2009:384506. doi: 10.1155/2009/384506. Epub 2009
Sep 10. PMID: 19753317; PMCID: PMC2742646.

12: Lee JK, Ghosh P, McWhorter V, Payne M, Olson R, Krinsky ML, Ramamoorthy S,
Carethers JM. Evidence for colorectal sarcomatoid carcinoma arising from
tubulovillous adenoma. World J Gastroenterol. 2008 Jul 21;14(27):4389-94. doi:
10.3748/wjg.14.4389. PMID: 18666331; PMCID: PMC2731194.

13: Ghosh P, Garcia-Marcos M, Bornheimer SJ, Farquhar MG. Activation of Galphai3
triggers cell migration via regulation of GIV. J Cell Biol. 2008 Jul
28;182(2):381-93. doi: 10.1083/jcb.200712066. PMID: 18663145; PMCID: PMC2483528.

14: Lee JK, Kum J, Ghosh P. Nonmetastatic cancer of the colon associated with
pyogenic liver abscess. Am J Gastroenterol. 2008 Mar;103(3):798-9. doi:
10.1111/j.1572-0241.2007.01612_1.x. PMID: 18341498.

15: Ghosh P, Olson RK, Harmon G. Sugar rush in the colon: why incidental findings
on PET scan justify colonoscopy? Am J Gastroenterol. 2007 Nov;102(11):2609-10.
doi: 10.1111/j.1572-0241.2007.01514_9.x. PMID: 17958772.

16: Ghosh P, Miyai K, Chojkier M. Gastric adenocarcinoma inducing portal
hypertension: a rare presentation. World J Gastroenterol. 2007 Feb
14;13(6):960-3. doi: 10.3748/wjg.v13.i6.960. PMID: 17352032; PMCID: PMC4065938.

17: Ghosh P, Kum J. Mesenteric panniculitis and sclerosing mesenteritis: a
continuum of inflammation fibrosis. Clin Gastroenterol Hepatol. 2007
May;5(5):A32. doi: 10.1016/j.cgh.2006.10.017. Epub 2007 Jan 29. PMID: 17261382.

18: Ghosh P, Strong C, Naugler W, Haghighi P, Carethers JM. Peritoneal mice
implicated in intestinal obstruction: report of a case and review of the
literature. J Clin Gastroenterol. 2006 May-Jun;40(5):427-30. doi:
10.1097/00004836-200605000-00012. PMID: 16721225.

19: Ghosh P, Carethers JM. Multiple "apple-core" lesions in chronic ischemic
colitis: the great masquerader. Am J Gastroenterol. 2009 Nov;104(11):2870-2.
doi: 10.1038/ajg.2009.397. PMID: 19888260; PMCID: PMC6701951.

20: Lee JK, Carethers JM, Ghosh P. ArterioVenous Malformation within Jejunal
Diverticulum: an unusual cause of massive gastrointestinal bleeding.
Gastroenterol Res Pract. 2009;2009:384506. doi: 10.1155/2009/384506. Epub 2009
Sep 10. PMID: 19753317; PMCID: PMC2742646.

21: Park FD, Lee JK, Madduri GD, Ghosh P. Generalized megaviscera of lupus:
refractory intestinal pseudo-obstruction, ureterohydronephrosis and
megacholedochus. World J Gastroenterol. 2009 Jul 28;15(28):3555-9. doi:
10.3748/wjg.15.3555. PMID: 19630114; PMCID: PMC2715985.


2004-2005:

9: Ghosh P, Kornfeld S. The GGA proteins: key players in protein sorting at the
trans-Golgi network. Eur J Cell Biol. 2004 Jul;83(6):257-62. doi:
10.1078/0171-9335-00374. PMID: 15511083.

10: Ghosh P, Kornfeld S. The cytoplasmic tail of the cation-independent mannose
6-phosphate receptor contains four binding sites for AP-1. Arch Biochem Biophys.
2004 Jun 15;426(2):225-30. doi: 10.1016/j.abb.2004.02.011. PMID: 15158672.


2003-2004:

5: Ghosh P, Griffith J, Geuze HJ, Kornfeld S. Mammalian GGAs act together to
sort mannose 6-phosphate receptors. J Cell Biol. 2003 Nov 24;163(4):755-66. doi:
10.1083/jcb.200308038. PMID: 14638859; PMCID: PMC2173681.

6: Ghosh P, Dahms NM, Kornfeld S. Mannose 6-phosphate receptors: new twists in
the tale. Nat Rev Mol Cell Biol. 2003 Mar;4(3):202-12. doi: 10.1038/nrm1050.
PMID: 12612639.

7: Ghosh P, Kornfeld S. AP-1 binding to sorting signals and release from
clathrin-coated vesicles is regulated by phosphorylation. J Cell Biol. 2003 Mar
3;160(5):699-708. doi: 10.1083/jcb.200211080. Epub 2003 Feb 25. PMID: 12604586;
PMCID: PMC2173368.

8: Ghosh P, Kornfeld S. Phosphorylation-induced conformational changes regulate
GGAs 1 and 3 function at the trans-Golgi network. J Biol Chem. 2003 Apr
18;278(16):14543-9. doi: 10.1074/jbc.M212543200. Epub 2003 Feb 10. PMID:
12578827.


2002-2003: 

1: Doray B*, Ghosh P*, Griffith J, Geuze HJ, Kornfeld S. Cooperation of GGAs and
AP-1 in packaging MPRs at the trans-Golgi network. Science. 2002 Sep
6;297(5587):1700-3. doi: 10.1126/science.1075327. PMID: 12215646. *Co-first author.

2: Doray B, Bruns K, Ghosh P, Kornfeld SA. Autoinhibition of the ligand-binding
site of GGA1/3 VHS domains by an internal acidic cluster-dileucine motif. Proc
Natl Acad Sci U S A. 2002 Jun 11;99(12):8072-7. doi: 10.1073/pnas.082235699.
PMID: 12060753; PMCID: PMC123022.

3: Do H, Lee WS, Ghosh P, Hollowell T, Canfield W, Kornfeld S. Human mannose
6-phosphate-uncovering enzyme is synthesized as a proenzyme that is activated by
the endoprotease furin. J Biol Chem. 2002 Aug 16;277(33):29737-44. doi:
10.1074/jbc.M202369200. Epub 2002 Jun 10. PMID: 12058031.

4: Doray B, Bruns K, Ghosh P, Kornfeld S. Interaction of the cation-dependent
mannose 6-phosphate receptor with GGA proteins. J Biol Chem. 2002 May
24;277(21):18477-82. doi: 10.1074/jbc.M201879200. Epub 2002 Mar 8. PMID:
11886874.