2017 - Present
The TBK1/IKKε inhibitor amlexanox improves dyslipidemia and prevents atherosclerosis
TANK-Binding Kinase 1 Regulates the Localization of Acyl-CoA Synthetase ACSL1 to Control Hepatic Fatty Acid Oxidation
Catecholamines suppress fatty acid re-esterification and increase oxidation in white adipocytes via STAT3
From overnutrition to liver injury: AMP-activated protein kinase in nonalcoholic fatty liver diseases
An AMPK-caspase-6 axis controls liver damage in nonalcoholic steatohepatitis
Bi-allelic Variants in RALGAPA1 Cause Profound Neurodevelopmental Disability, Muscular Hypotonia, Infantile Spasms, and Feeding Abnormalities
Neutralization of Oxidized Phospholipids Ameliorates Non-alcoholic Steatohepatitis
YIPF6 controls sorting of FGF21 into COPII vesicles and promotes obesity
Hyaluronan as a potential thermogenic rheostat
Synthesis of deuteirum-labelled amlexanox and its metabolic stability against mouse, rat and human microsomes
ER Stress Drives Lipogenesis and Steatohepatitis via Caspase-2 Activation of S1P.
Carboxylic Acid Derivatives of Amlexanox Display Enhanced Potency toward TBK1 and IKKε and Reveal Mechanisms for Selective Inhibition.
RalA controls glucose homeostasis by regulating glucose uptake in brown fat.
ERRγ Preserves Brown Fat Innate Thermogenic Activity.
TBK1 at the Crossroads of Inflammation and Energy Homeostasis in Adipose Tissue.
Lipotoxicity induces hepatic protein inclusions through TANK binding kinase 1-mediated p62/sequestosome 1 phosphorylation.
Vinexin family (SORBS) proteins play different roles in stiffness-sensing and contractile force generation.
Creatine Fuels the Thermic Effect of Feeding.
Adapting to obesity with adipose tissue inflammation.
Inhibition of IKKɛ and TBK1 Improves Glucose Control in a Subset of Patients with Type 2 Diabetes.
Phosphorylation of the exocyst protein Exo84 by TBK1 promotes insulin-stimulated GLUT4 trafficking.
Inflammatory mechanisms linking obesity and metabolic disease.
View all publications on PubMed