Insulin resistance causes the epidemic diseases of our era...

but it is invisible even to trained clinical eyes.

Translational investigation of insulin resistance and cardio-metabolic diseases

See our recent publications

Get to know our lab members
Join our team

The Majithia lab is recruiting talented and enthusiastic scientists at all levels to join our group!

Our Mission: Develop new ways to detect and treat insulin resistance 

We study human insulin resistance using the tools of human genetics and functional genomics. Our goal is to diagnose patients and identify therapeutic targets for cardiometabolic diseases-- diabetes, heart attacks, strokes and fatty liver

Learn More
 

Our Approach:

Genotype-Function-Phenotype

We apply a multi-disciplinary approach to investigation—
grounded in human genetics, clarified through systematic, high throughput cellular experimentation, and calibrated by its relevance to disease. 
1. Genotype: human genetic/genomic variation; genome engineering 
2. Function: massively parallel, disease-calibrated cellular assays; serum/tissue biomarkers 
3. Phenotype: clinical trial outcomes and real-world patient health data


Our Research Programs


lab logo with genotype square enlarged

Therapeutic Target Identification

Therapeutic Target Identification

Identify genes that protect from insulin resistance
lab logo with genotype square enlarged
lab logo with function pentagon enlarged

Individually tailored therapy

lab logo with phenotype circle enlarged

Next-generation phenotyping



Lab News and Announcements

biology clipartOct 08, 2019: Open position for a post-doctoral fellows

The Majithia Lab is conducting an open search for post-doctoral fellows. Learn more about our team and the position here.

Show additional content areas below