DRC Genomics and Epigenetics Core

​Sven Heinz, PhD

Core Director
sheinz@health.ucsd.edu​

Kristen Jepsen, PhD

Core Co-Director
kjepsen@ucsd.edu

The DRC Epigenetic and Genomics Core (EGC) is a state-of-the-art facility that facilitates high-throughput genomic approaches. High-throughput sequencing, data acquisition and analysis require expensive instrumentation and reagents and a highly skilled team of individuals who are experts in specific components of the overall procedure. These technologies therefore lie beyond the scope of most individual laboratories. The EGC, which is comprised of the Institute for Genomic Medicine (IGM)and the Center for Computational Biology and Bioinformatics, has been instrumental in providing DRC investigators access to these technologies. The EGC also provides consultation and training of students, postdoctoral fellows, investigators and technical staff regarding high-throughput sequencing methodologies and data analysis which is overseen by the Functional Genomics Specialist. Genomics services are available to the DRC community at subsidized rates. 

IGM Genomics Center:
Director: Kristen Jepsen, PhD
Leichtag 184
858-822-4231

kjepsen@ucsd.edu
igmsamplesubmission@ucsd.edu

Services: The UCSD IGM Genomics Center offers full services in high-throughput sequencing and whole-genome genotyping and copy number variation analysis (see Services). The IGM Genomics Center offers assay design consultation, sequencing library preparation (DNA/RNA/smallRNA/targeted sequencing), single cell RNA sequencing (10X Genomics), lllumina platform sequencing (MiSeq, HiSeq2500, HiSeq4000 and NovaSeq 6000), PacBio SMRT sequencing and Illumina genotyping and methylation arrays.

Center for Computational Biology and Bioinformatics:
Executive Director: Kathleen Fisch, PhD​
Associate Director: Brin Rosenthal, PhD
sbrosenthal@health.ucsd.edu

Contact: CCBB web form​

Services: CCBB offers a wide variety of analytical services, including high-throughput sequencing analyses, transcriptomics, genomics, epigenomics, metagenomics, microbiome, CRISPR screens, network analysis, and custom analytical pipelines and algorithm development.

Functional Genomics Specialist:
Nathanael Spann, PhD

Services:The Functional Genomics Specialist will support DRC investigators through consultation, training (both theoretical and physical) and/or collaboration as determined by contextually defined needs of individual researchers. This may include advising investigators on appropriate Genomics methods application, experimental setup and experimental planning aimed at allowing efficient advancement of their research via implementation of high-throughput sequencing.